Results 291 to 300 of about 464,133 (328)

Notch1 and Major Vault Proteins Modulate Temozolomide Resistance in Glioblastoma. [PDF]

J Cell Mol Med
Tuncer C, Hacioglu C.
europepmc   +1 more source

Adverse drug events associated with insulin glargine: a real-world pharmacovigilance study based on the FAERS database. [PDF]

Front Pharmacol
Wang T, He G, Xiong W, Huang J.
europepmc   +1 more source

Unveiling drug resistance pathways in high-grade serous ovarian cancer(HGSOC): recent advances and future perspectives. [PDF]

Front Immunol
Fu R, Hu R, Li W, Lv X, Zhao H, Li F.
europepmc   +1 more source

F-box protein 22: A prognostic biomarker for colon cancer associated with immune infiltration and chemotherapy resistance. [PDF]

World J Gastrointest Oncol
Lu XF, Zhang HW, Chang X, Guo YZ.
europepmc   +1 more source

Assessment of chromatin remodeling of acute myeloid leukemia cells treated with gilteritinib: a case report. [PDF]

J Med Case Rep
Mori J, Sawada T, Nojiri K, Kanemoto Y, Okada T, Kurokawa T, Kato S.   +6 more
europepmc   +1 more source

Artificial intelligence networks for assessing the prognosis of gastrointestinal cancer to immunotherapy based on genetic mutation features: a systematic review and meta-analysis. [PDF]

BMC Gastroenterol
Norouzkhani N, Mobaraki H, Varmazyar S, Zaboli H, Mohamadi Z, Nikeghbali G, Bagheri K, Marivany N, Najafi M, Nozad Varjovi M, Abouzeid M, Zeidi Baghrabad H, Eini P, Azhdarimoghaddam A, Khosravi F, Asadi Anar M.   +15 more
europepmc   +1 more source

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Absence of terminal deoxynucleotidyl transferase expression in T‐ALL/LBL accumulates chromosomal abnormalities to induce drug resistance

International Journal of Cancer, 2023
T‐acute lymphoblastic leukemia/lymphoma (T‐ALL/LBL) is a malignant neoplasm of immature lymphoblasts. Terminal deoxynucleotidyl transferase (TDT) is a template‐independent DNA polymerase that plays an essential role in generating diversity for ...
Hui Xiao, Siqi Wang, Yuejia Tang, Shan-shan Li, Yufeng Jiang, Yi Yang, Yinwen Zhang, Yali Han, Xiaoyu Wu, Liang Zheng, Yanxin Li, Yi-hong Gao   +11 more
semanticscholar   +1 more source

miR‐218 contributes to drug resistance in multiple myeloma via targeting LRRC28

Journal of Cellular Biochemistry, 2021
Multiple myeloma (MM) is a malignant neoplasm featured by obvious drug resistance and poor prognosis. MicroRNAs (miRNAs) are a class of small noncoding RNAs with crucial roles in many biological processes including cancer initiation and progression.
Haifei Chen, Weiling Cao, Jiao Chen, Danbo Liu, Lingyun Zhou, Fang Du, Feiqi Zhu   +6 more
semanticscholar   +1 more source

Anti-evolution Drugs: A New Paradigm to Combat Drug Resistance

Letters in Drug Design & Discovery, 2021
The drug resistance confronts chemotherapy of neoplasm and microbial infections. A vast array of molecular mechanisms was implicated in drug resistance, including, generation of drug efflux transporters, mutation of drug targets, and alteration of drug
R. Peraman, Santhivardhan Chinni, Sathish Kumar Sure, Vinay Kumar Kutagulla, Muthukumaran Peraman, Azger VN, Padmanabha Reddy Y   +6 more
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MYC Upregulation Confers Resistance to Everolimus and Establishes Vulnerability to Cyclin-Dependent Kinase Inhibitors in Pancreatic Neuroendocrine Neoplasm Cells

Neuroendocrinology, 2020
Introduction: Dysregulation of the mechanistic target of rapamycin complex 1 (mTORC1)-dependent pathways in pancreatic neuroendocrine neoplasms (PanNENs) underlies the introduction of the mTORC1 inhibitor everolimus as treatment of advanced progressive ...
F. Terracciano, A. Capone, A. Montori, M. Rinzivillo, S. Partelli, F. Panzuto, E. Pilozzi, P. Arcidiacono, C. Sette, G. Capurso   +9 more
semanticscholar   +1 more source