Results 191 to 200 of about 7,313,278 (356)

Trial of Bronchodilator Drugs Given by Metered Aerosol with a Comparison of Two Bedside Methods of Estimating Airway Resistance [PDF]

, 1966
B I Hoffbrand, M. I. Hoffbrand, Iain D. Hill, P J D Heaf   +3 more
openalex   +1 more source

Small modifier, big decision: switching to SUMO mode adds weight to cancer stemness in mammary tumors

Molecular Oncology, EarlyView.
Inhibition of protein SUMOylation has been shown to block tumorigenesis; however, the specific mechanisms by which SUMOylation controls the tumor‐initiating capacities remain elusive. Li et al. describe the role of Etv1 SUMOylation in cancer stem cells using mouse models of mammary gland tumorigenesis.
Veronika Yevdokimova, Yannick D. Benoit
wiley   +1 more source

Dr. Kinase: predicting the drug-resistance hotspots of protein kinases. [PDF]

Nucleic Acids Res
Lin S, Tu C, Hu R, Wang H, Dong Z, Luo H, Kuang L, Wang T, Wang L, Zhao Z, Li Z, Xu H.   +11 more
europepmc   +1 more source

Drug Resistance as Influenced by Inactivated Sensitivity Discs1 [PDF]

, 1968
Lewis J. Griffith, C. G. Mullins
openalex   +1 more source

Targeting carbonic anhydrase IX/XII prevents the anti‐ferroptotic effect of stromal lactic acid in prostate carcinoma

Molecular Oncology, EarlyView.
In prostate carcinoma, lactic acid, secreted by highly glycolytic cancer‐associated fibroblasts, is imported into tumor cells through the MCT1 transporter and prevents RSL3 and erastin‐induced ferroptosis (A). Targeting of carbonic anhydrase IX/XII, the main extracellular pH regulators, in tumor and stromal cells reduces microenvironmental acidosis and
Elisa Pardella, Giuseppina Comito, Luigi Ippolito, Erica Pranzini, Marta Iozzo, Giulia Gangarossa, Francesca Virgilio, Silvia Bua, Alessio Nocentini, Giada Sandrini, Nicla Lorito, Marina Bacci, Gabriella Nesi, Pietro Spatafora, Sergio Serni, Claudiu T. Supuran, Andrea Morandi, Paola Chiarugi, Elisa Giannoni   +18 more
wiley   +1 more source

Artificial intelligence in drug resistance management. [PDF]

3 Biotech
Elalouf A, Elalouf H, Rosenfeld A, Maoz H.   +3 more
europepmc   +1 more source

Transferable drug resistance. [PDF]

, 1969

openalex   +1 more source

The critical role of DNA damage‐inducible transcript 4 (DDIT4) in stemness character of leukemia cells and leukemia initiation

Molecular Oncology, EarlyView.
Stemness properties, including quiescence, self‐renewal, and chemoresistance, are closely associated with leukemia relapse. Here, we demonstrate that DNA damage‐inducible transcript 4 (DDIT4) is induced in the hypoxic bone marrow niche and is essential for maintaining the stemness of AML1‐ETO9a leukemia cells.
Yishuang Li, Zhijie Cao, Haiyan Xing, Zhenya Xue, Wenbing Liu, Jiayuan Chen, Yihan Mei, Runxia Gu, Hui Wei, Shaowei Qiu, Min Wang, Qing Rao, Jianxiang Wang   +12 more
wiley   +1 more source

Drug Resistance: The Role of Sphingolipid Metabolism. [PDF]

Int J Mol Sci
Zhakupova A, Zeinolla A, Kokabi K, Sergazy S, Aljofan M.   +4 more
europepmc   +1 more source

Episome-mediated Transfer of Drug Resistance in Enterobacteriaceae X. Restriction and Modification of Phages by fi− R Factors

, 1966
Tsutomu Watanabe, Toshiya Takano, Toshihiko Arai, Hiroshi Nishida, Sachiko Sato   +4 more
openalex   +1 more source