Results 201 to 210 of about 2,275,826 (357)

NCAM1 (CD56) promotes leukemogenesis and confers drug resistance in AML [PDF]

, 2019
Daniel Sasca, Jakub Szybinski, Andrea Schüler, Viral Shah, Jan B. Heidelberger, Patricia S. Haehnel, Anna Dolnik, Oliver Kriege, Eva-Marie Fehr, Wolf Henning Gebhardt, George Reid, Claudia Scholl, Matthias Theobald, Lars Bullinger, Petra Beli, Thomas Kindler   +15 more
openalex   +1 more source

KLK7 overexpression promotes an aggressive phenotype and facilitates peritoneal dissemination in colorectal cancer cells

FEBS Open Bio, EarlyView.
KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani, Tobias Dreyer, Meriem Naim, Rea Lo Dico, Natalia A. Ignatenko, Viktor Magdolen, Dalila Darmoul   +6 more
wiley   +1 more source

Drug resistance in glioblastoma: Challenges, mechanisms and therapeutic strategies (Review). [PDF]

Mol Clin Oncol
Durga YK, Pusapati RV.
europepmc   +1 more source

Modeling the dynamics of tuberculosis with drug resistance in North Shoa Zone, Oromiya Regional State, Ethiopia

, 2021

openalex   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

FEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point, Wafaa Achache, Janïs Laudouze, Eliana Sepulveda Ramos, Mickaël Maziero, Céline Crauste, Stéphane Canaan, Pierre Santucci   +7 more
wiley   +1 more source

A Bibliometric Analysis of Drug Resistance in Pediatric Acute Lymphoblastic Leukemia. [PDF]

Adv Biomed Res
Khanahmad A, Khazaee-Nasirabadi MH, Lotfi M, Hami A.   +3 more
europepmc   +1 more source

Genome-scale analysis of Methicillin-resistant Staphylococcus aureus USA300 reveals a tradeoff between pathogenesis and drug resistance [PDF]

, 2018
Donghui Choe, Richard Szubin, Samira Dahesh, Suhyung Cho, Victor Nizet, Bernhard Ø. Palsson, Byung‐Kwan Cho   +6 more
openalex   +1 more source

Adverse Events and Drug Resistance in Critically Ill Patients Treated with Colistimethate Sodium: A Review of the Literature

, 2023
Víctor Hugo Ahumada-Topete, Kevin Jesus de Dios Sanchez, Gustavo Alejandro Casas Aparicio, Graciela Hernández Silva, Cesar Emmanuel Lopez Vejar, Luz María Torres‐Espíndola, Arnoldo Aquíno-Gálvez, Odalis Rodriguez Ganen, Manuel Castillejos‐López   +8 more
openalex   +2 more sources

Anticancer sensitivities and biological characteristics of HCT116 cells resistant to the selective poly(ADP‐ribose) glycohydrolase inhibitor

FEBS Open Bio, EarlyView.
We analyzed alterations of PAR metabolism‐related proteins in PARG inhibitor‐resistant HCT116RPDD cells. Although PARG levels remained unchanged, HCT116RPDD cells exhibited reduced PARP1 and ARH3 expression and elevated PAR levels. Interestingly, HCT116RPDD cells exhibited slightly elevated intracellular NAD+/NADH and ATP levels. Our findings suggest a
Kaede Tsuda, Yoko Ogino, Akira Sato
wiley   +1 more source

Lactylation in Cancer: Unlocking the Key to Drug Resistance and Therapeutic Breakthroughs. [PDF]

Oncol Res
Feng X, Li D, Wang P, Li X, Li G.
europepmc   +1 more source