Results 211 to 220 of about 7,313,278 (356)

Nicotinamide N‐methyltransferase promotes drug resistance in lung cancer, as revealed by nascent proteomic profiling

Molecular Oncology, EarlyView.
AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou, Zhen Wang, Fei Yang, Xiao Han, Lei Li, Huadong Liu   +5 more
wiley   +1 more source

Population genetic approaches to estimating the size of the HIV reservoir

Journal of Virus Eradication, 2015
J. Hattori, V. Boltz, W. Shao, M. Kearney, F. Maldarelli   +4 more
doaj  

Human Gut Bacteriophageome: Insights Into Drug Resistance Mechanisms in Tuberculosis. [PDF]

Interdiscip Perspect Infect Dis
Jafari E, Azizian R, Tabasi M, Banakar M, Bagheri Lankarani K.   +4 more
europepmc   +1 more source

STUDIES ON TRANSFERABLE DRUG RESISTANCE IN BACTERIA [PDF]

, 1962
Masanosuke Yoshikawa, Tomoichiro Akiba
openalex   +1 more source

Understanding and measuring mechanical signals in the tumor stroma

FEBS Open Bio, EarlyView.
This review discusses cancer‐associated fibroblast subtypes and their functions, particularly in relation to extracellular matrix production, as well as the development of 3D models to study tumor stroma mechanics in vitro. Several quantitative techniques to measure tissue mechanical properties are also described, to emphasize the diagnostic and ...
Fàtima de la Jara Ortiz, Chiara Cimmino, Maurizio Ventre, Alessandra Cambi   +3 more
wiley   +1 more source

The role and mechanism of fatty acid oxidation in cancer drug resistance. [PDF]

Cell Death Discov
Lei Y, Cai S, Zhang JK, Ding SQ, Zhang ZH, Zhang CD, Dai DQ, Li YS.   +7 more
europepmc   +1 more source

Starving Drug Resistance

HemaSphere, 2020
openaire   +3 more sources

Bioengineering facets of the tumor microenvironment in 3D tumor models: insights into cellular, biophysical and biochemical interactions

FEBS Open Bio, EarlyView.
The tumor microenvironment is a dynamic, multifaceted complex system of interdependent cellular, biochemical, and biophysical components. Three‐dimensional in vitro models of the tumor microenvironment enable a better understanding of these interactions and their impact on cancer progression and therapeutic resistance.
Salma T. Rafik, Deniz Bakkalci, Alexander J. MacRobert, Umber Cheema   +3 more
wiley   +1 more source

Genomic dissection of nosocomial multiclonal-outbreak by carbapenem-resistant Pseudomonas aeruginosa strains in a tertiary children’s hospital in Japan

Journal of Global Antimicrobial Resistance
Objective: Carbapenem-resistant Pseudomonas aeruginosa (CRPA) is an important antimicrobial-resistant bacterial pathogen. We observed an increase in the detection rate of CRPA isolates at a tertiary children’s hospital in Japan.
Akihiko Shimizu, Jun Kurushima, Koichi Tanimoto, Naoko Tomie, Yusuke Hashimoto, Takahiro Nomura, Natsuko Ota, Hidetada Hirakawa, Haruyoshi Tomita   +8 more
doaj  

Intratumoral heterogeneity and drug resistance in cancer. [PDF]

Cancer Cell Int
Fu YC, Liang SB, Luo M, Wang XP.
europepmc   +1 more source