Results 221 to 230 of about 1,232,228 (310)

Effects of recombination on multi-drug resistance evolution in Plasmodium falciparum malaria. [PDF]

PLoS Comput Biol
Tran KT, Nguyen TD, Weissman DB, Li EZ, Mok S, Small-Saunders JL, Bousema T, Zupko RJ, Tran TN, Boni MF.   +9 more
europepmc   +1 more source

ON THE DRUG-RESISTANCE OF SHIGELLA ISOLATED IN 1959 IN GUNMA PREFECTURE AND THEIR EPIDEMIOLOGICAL PROBLEM

, 1960
Kenji Harada, Mitsuo Kameda, Mitsue Suzuki, Tatsuo Matsuyama, Shigeto Komiyama, Susumu Mitsuhashi, Hajime Hashimoto   +6 more
openalex   +2 more sources

Production of antibacterial compounds by a Steely hybrid polyketide synthase in Dictyostelium

FEBS Open Bio, EarlyView.
By selecting appropriate production species under optimised culture conditions, new chlorinated dibenzofuran compounds, which previously could not be analysed in sufficient quantities, were identified from cellular slime mould fruiting bodies. The strong antibacterial activity exhibited by these compounds suggests a link to the ecological function of ...
Tomoaki R. Yamashita, Toyonobu Usuki, Robert R. Kay, Tamao Saito   +3 more
wiley   +1 more source

PCK1 and ALDH1A1 are identified as biomarkers for inherent drug resistance in hepatocellular carcinoma. [PDF]

Discov Oncol
Chen W, Zhou C, Liu G, Wang X, Yi Y, Xu Y, Qiu S.   +6 more
europepmc   +1 more source

Lactoferrin treatment activates acetylcholinesterase, decreasing acetylcholine levels in non‐small cell lung cancer (NSCLC) cell culture supernatants, inhibiting cell survival

FEBS Open Bio, EarlyView.
Representation of the suggested mode of action of lactoferrin (Lf) in nonsmall cell lung cancer (NSCLC) A549 cells. Lf induces activation of caspase‐3 by activating p53 and AChE leading to decreased ACh concentrations. In turn, ACh signaling leads to activation of VEGF and AKT and blocking of caspase‐3.
Stuti Goel, Caroline Wozniak, Aya Sabri, Ben Haddad, Brooke Lopo, Alvaro Cobos, Sarah Sarofim, Jeffrey Guthrie, Deborah Heyl, Hedeel Guy Evans   +9 more
wiley   +1 more source

Antimicrobial Resistance Cartography: A Generalisable Framework for Studying Multivariate Drug Resistance

Balmer AJ, Murray GGR, Lo S, Restif O, Weinert LA.   +4 more
europepmc   +1 more source

Artificial intelligence in drug resistance management. [PDF]

3 Biotech
Elalouf A, Elalouf H, Rosenfeld A, Maoz H.   +3 more
europepmc   +1 more source

Indoleamine 2,3‐dioxygenase 1 inhibition reverses cancer‐associated fibroblast‐mediated immunosuppression in high‐grade serous ovarian cancer

FEBS Open Bio, EarlyView.
CAF‐mediated immunosuppression in ovarian cancer is driven by IDO1, reducing T‐cell function. Inhibiting IDO1 restores T‐cell proliferation and cytotoxicity, increases cancer cell apoptosis, and may help overcome CAF‐induced immune suppression in high‐grade serous ovarian cancer. Targeting IDO1 may improve antitumor immunity.
Hyewon Lee, Jung Yoon Ho, In Sun Hwang, Youn Jin Choi   +3 more
wiley   +1 more source

Drug Resistance: The Role of Sphingolipid Metabolism. [PDF]

Int J Mol Sci
Zhakupova A, Zeinolla A, Kokabi K, Sergazy S, Aljofan M.   +4 more
europepmc   +1 more source