Mitochondria contain two mitoribosome rescue factors, ICT1 and MTRFR (C12orf65). ICT1 also functions as a mitoribosomal protein in mice and humans, and its loss is lethal. Although Mtrfr knockout mice could not be generated, knockout zebrafish lines for ict1 and mtrfr were established.
Nobukazu Nameki+11 more
wiley +1 more source
Emerging Multifunctional Biomaterials for Addressing Drug Resistance in Cancer. [PDF]
El-Tanani M+5 more
europepmc +1 more source
Epidemiological and Genetical Study of Drug Resistance in Staphylococcus aureus [PDF]
Susumu Mitsuhashi
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Identifying prognostic targets in metastatic prostate cancer beyond AR
Genome‐wide functional screens combined with a large gene expression database and clinical outcomes can identify new therapeutic vulnerabilities in prostate cancer. Eight potentially druggable targets demonstrated strong dependency in cell lines, were associated with worse prognosis clinically, and showed evidence of protein expression in prostate ...
Emily Feng+13 more
wiley +1 more source
Aspergillosis: A comprehensive review of pathogenesis, drug resistance, and emerging therapeutics. [PDF]
Singh A, Singh J, Kumar S.
europepmc +1 more source
Drug Resistance of Enteric Bacteria VIII. Chromosomal Location of Nontransferable R Factor inEscherichia coli [PDF]
Kenji Harada+4 more
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Current trends in single‐cell RNA sequencing applications in diabetes mellitus
Single‐cell RNA sequencing is a powerful approach to decipher the cellular and molecular landscape at a single‐cell resolution. The rapid development of this technology has led to a wide range of applications, including the detection of cellular and molecular mechanisms and the identification and introduction of novel potential diagnostic and ...
Seyed Sajjad Zadian+6 more
wiley +1 more source
Unique pathological features and drug resistance patterns in cutaneous tuberculosis. [PDF]
Liu Y+7 more
europepmc +1 more source
The selectivity of action of alkylating agents and drug resistance. II. A comparison of the effects of alkylating drugs on growth inhibition and cell size in sensitive and resistant strains of the Yoshida ascites sarcoma. [PDF]
Kenneth R. Harrap, Bridget T. Hill
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