Results 231 to 240 of about 8,379,718 (351)

Cis‐unsaturated sphingolipids support growth of sphingoid base‐deficient yeast but impair plasma membrane integrity

FEBS Open Bio, EarlyView.
Sphingoid base structures, the sphingolipid backbones, vary among species. We established yeast cells in which the native sphingoid base was replaced with plant‐type bases containing cis or trans double bonds. This is, to our knowledge, the first eukaryotic model mostly composed of sphingolipids containing cis‐unsaturated sphingoid base, providing a ...
Takashi Higuchi, Saki Sugihara, Yohei Ishibashi, Kono Yushi, Hazuki Yamauchi, Motohiro Tani   +5 more
wiley   +1 more source

Effects of recombination on multi-drug resistance evolution in Plasmodium falciparum malaria. [PDF]

PLoS Comput Biol
Tran KT, Nguyen TD, Weissman DB, Li EZ, Mok S, Small-Saunders JL, Bousema T, Zupko RJ, Tran TN, Boni MF.   +9 more
europepmc   +1 more source

Transferable Drug Resistance Among Enterobacteriaceae Isolated from Human Urinary Tract Infections [PDF]

, 1969
Donna G. Sieckmann, Norman D. Reed, Carl E. Georgi   +2 more
openalex   +1 more source

Stromagenesis and cancer‐associated fibroblast heterogeneity in primary tumors and metastasis: focus in non‐small cell lung cancer

FEBS Open Bio, EarlyView.
Cancer‐associated fibroblasts (CAFs) play different roles in NSCLC progression and metastasis. Their heterogeneous origins and phenotypes shape the tumor microenvironment and influence metastatic spread. This review highlights NSCLC CAF subtypes, their potential cellular sources, and their differential distribution across primary tumors and distant ...
Alejandro Bernardo, Natalia Díaz‐Valdivia, Patricia Fernández‐Nogueira, Jordi Alcaraz   +3 more
wiley   +1 more source

PCK1 and ALDH1A1 are identified as biomarkers for inherent drug resistance in hepatocellular carcinoma. [PDF]

Discov Oncol
Chen W, Zhou C, Liu G, Wang X, Yi Y, Xu Y, Qiu S.   +6 more
europepmc   +1 more source

Drug Resistance as Influenced by Inactivated Sensitivity Discs1 [PDF]

, 1968
Lewis J. Griffith, C. G. Mullins
openalex   +1 more source

Microbial profile of the appendix niche in acute appendicitis: a novel sampling approach

FEBS Open Bio, EarlyView.
This study utilized a novel sampling method, ERAT (i.e. endoscopic retrograde appendicitis treatment)‐guided lumen aspiration, to obtain samples from the appendix, and shotgun metagenomic sequencing was performed for in situ characterization of the appendix microbiome in patients with acute appendicitis.
Huimin Ma, Mingfei Wang, Yanhu Feng, Wanqi Zhang, Wenbo Wang, Yanfeng Xie, Guixiang Kong, Jie Feng, Pengfei Wang, Qi Wang, Xiaojun Huang   +10 more
wiley   +1 more source

Artificial intelligence in drug resistance management. [PDF]

3 Biotech
Elalouf A, Elalouf H, Rosenfeld A, Maoz H.   +3 more
europepmc   +1 more source

Transcriptional regulation of neuropeptide receptors underlies context‐dependent adaptation in Drosophila melanogaster

FEBS Open Bio, EarlyView.
Under environmental changes, the expression level of neuropeptide (NP) and neuropeptide receptor (NPR) genes changes to confer context‐dependent adaptation to the model organism Drosophila melanogaster. Through finding more regulatory elements in the NPR genes in comparison with their ligands (NPs), we found that NPR‐biased transcriptional regulation ...
SeungHeui Ryu, Yanan Wei, Zekun Wu, Tianmu Zhang, DoHoon Lee, Hadi Najafi, Woo Jae Kim   +6 more
wiley   +1 more source

Drug resistance and tumor heterogeneity: cells and ensembles. [PDF]

Biophys Rev
Nussinov R, Yavuz BR, Jang H.
europepmc   +1 more source