Results 231 to 240 of about 2,311,261 (354)

Drug resistance in cancer: molecular mechanisms and emerging treatment strategies. [PDF]

Mol Biomed
Li J, Hu J, Yang Y, Zhang H, Liu Y, Fang Y, Qu L, Lin A, Luo P, Jiang A, Wang L.   +10 more
europepmc   +1 more source

Anticancer sensitivities and biological characteristics of HCT116 cells resistant to the selective poly(ADP‐ribose) glycohydrolase inhibitor

FEBS Open Bio, EarlyView.
We analyzed alterations of PAR metabolism‐related proteins in PARG inhibitor‐resistant HCT116RPDD cells. Although PARG levels remained unchanged, HCT116RPDD cells exhibited reduced PARP1 and ARH3 expression and elevated PAR levels. Interestingly, HCT116RPDD cells exhibited slightly elevated intracellular NAD+/NADH and ATP levels. Our findings suggest a
Kaede Tsuda, Yoko Ogino, Akira Sato
wiley   +1 more source

Understanding Non-Small-Cell Lung Cancer: Biology, Therapeutics and Drug Resistance. [PDF]

Biomedicines
Ahluwalia P, Kolhe R, Rojiani M.
europepmc   +1 more source

Tumor‐stromal crosstalk and macrophage enrichment are associated with chemotherapy response in bladder cancer

FEBS Open Bio, EarlyView.
Chemoresistance in bladder cancer: Macrophage recruitment associated with CXCL1, CXCL5 and CXCL8 expression is characteristic of Gemcitabine/Cisplatin (Gem/Cis) Non‐Responder tumors (right side) while Responder tumors did not show substantial tumor‐stromal crosstalk (left side). All biological icons are attributed to Bioicons: carcinoma, cancerous‐cell‐
Sophie Leypold, Janik Riese, Lancelot Seillier, Mark Kühnel, Julia Pannhausen, Charlotte O. J. Fröhlich, Christian Martin, Peter Boor, Matthias Saar, Danny D. Jonigk, Nadine T. Gaisa, Michael Rose   +11 more
wiley   +1 more source

The role of cytokines in ovarian cancer drug resistance. [PDF]

Int J Cancer
Wang L, Zang Y, Dejenie R, Bing J, Dong S, Zhang Y, Zhu Y, Li J.   +7 more
europepmc   +1 more source

Antimicrobial Drug Resistance AND#8211; A global concern

, 2010
P.T.A. Usha, Sabitha Jose and A.R. Nisha
openalex   +1 more source

Antimicrobial drug use and its association with antimicrobial resistance in fecal commensals from cows on California dairies [PDF]

Essam M. Abdelfattah, Pius S. Ekong, Emmanuel Okello, Tapakorn Chamchoy, Betsy M. Karle, Randi A. Black, Wagdy R. ElAshmawy, David B. Sheedy, Deniece R. Williams, Terry W. Lehenbauer, Barbara A. Byrne, Sharif S. Aly   +11 more
openalex   +1 more source

The role of lipid metabolism in neuronal senescence

FEBS Open Bio, EarlyView.
Disrupted lipid metabolism, through alterations in lipid species or lipid droplet accumulation, can drive neuronal senescence. However, lipid dyshomeostasis can also occur alongside neuronal senescence, further amplifying tissue damage. Delineating how lipid‐induced senescence emerges in neurons and glial cells, and how it contributes to ageing and ...
Dikaia Tsagkari, Eleftheria Panagiotidou, Nektarios Tavernarakis   +2 more
wiley   +1 more source

Regulation of drug resistance in bladder urothelial carcinoma by tumor aerobic glycolysis. [PDF]

J Transl Med
Weng C, Deng H, Yang Z, Zeng X, Xu H, Li J, Yu C.   +6 more
europepmc   +1 more source

Drug Resistance and Detection of R Factors among Fecal <I>Escherichia coli</I> Strains Isolated from Laboratory Animals

, 1973
Pahom SUNDARA, M Kashiwazaki
openalex   +2 more sources