Results 281 to 290 of about 8,234,457 (404)

Recent developments in using mechanistic cardiac modelling for drug safety evaluation

Drug Discovery Today, 2016
M. Davies, Ken Wang, Gary R. Mirams, A. Caruso, D. Noble, A. Walz, T. Lavé, F. Schuler, T. Singer, L. Polonchuk   +9 more
semanticscholar   +1 more source

Region‐to‐Region Unidirectional Connection In Vitro Brain Model for Studying Directional Propagation of Neuropathologies

Advanced Functional Materials, EarlyView.
A unidirectional cerebral organoid–organoid neural circuit is established using a microfluidic platform, enabling controlled directional propagation of electrical signals, neuroinflammatory cues, and neurodegenerative disease–related proteins between spatially separated organoids.
Kyeong Seob Hwang, Hui‐Wen Liu, Hyogeun Shin, Hyun Wook Kang, Minjin Kang, Jongbaeg Kim, Il‐Joo Cho, Nakwon Choi, Seok Chung, Hong Nam Kim   +9 more
wiley   +1 more source

REMS Logic Model: A Pragmatic Framework for Incorporating Drug Safety into Clinical Practice. [PDF]

Drug Saf
Toyserkani GA, Robottom SB, Morrato EH.
europepmc   +1 more source

Protecting Public Health from Outside the Physician's Office: A Century of FDA Regulation from Drug Safety Labeling to Off-Label Drug Promotion

, 2007
Katherine Helm
openalex   +1 more source

High‐Spatiotemporal‐Resolution Transparent Thermoelectric Temperature Sensor Arrays Reveal Temperature‐Dependent Windows for Reversible Photothermal Neuromodulation

Advanced Functional Materials, EarlyView.
Thermoelectric temperature sensors are developed that directly measure heat changes during optical‐based neural stimulation with millisecond precision. The sensors reveal the temperature windows for safe reversible neural modulation: 1.4–4.5 °C enables reversible neural inhibition, while temperatures above 6.1 °C cause permanent thermal damage.
Junhee Lee, Dongjo Yoon, Jungha Lee, Duhee Kim, Eunui Kim, Jong‐Hyeok Yoon, Hyuk‐Jun Kwon, Seungjun Chung, Yoonkey Nam, Hongki Kang   +9 more
wiley   +1 more source

A genomic-led strategy to anticipate drug safety effects

Ferolito BR, Horimoto AR, Gravel-Pucillo K, Golden DJ, Dashti H, Giambartolomei C, Rasooly D, Matty R, Gaziano L, Tsepilov Y, Costa L, Kosik N, Ioannidis H, Karim M, Winicki G, Hunter F, Langenberg C, Whittaker JC, Million Veteran Program, Cai T, Peloso GM, Zdrazil B, Ghoussaini M, Leach AR, Muralidhar S, Smit IA, Casas JP, Gaziano JM, Cho K, Pereira AC.   +29 more
europepmc   +1 more source

Social media as a source of drug safety information in the paediatric population. [PDF]

Br J Clin Pharmacol
Vilimelis-Piulats I, Pérez-Ricart A, Peligero MB, Calvo A, Negre JMS, Juárez-Gimenez JC.   +5 more
europepmc   +1 more source

Data Sheet 1_Efficacy and safety of nebulized drugs in the treatment of non-severe mycoplasma pneumoniae pneumonia in children - a network meta-analysis.pdf

Li Zeng (77324), Hanlin Ye (22163584), Qiu Zhang (239441), Ting Xu (215531), Hong Xu (71477), Dan Bi (2437678)   +5 more
openalex   +1 more source

Drug-Induced QT Prolongation: Individual Susceptibility and Regulatory Issues Related to Safety Pharmacology 5. QT Interval: Gender and Other Affecting Factors in the Clinical Setting

, 2006
Tetsunori Saikawa
openalex   +2 more sources