Results 171 to 180 of about 8,084,609 (393)

Validation of High-Performance Liquid Chromatography for determination and stability assessment of dobutamine hydrochloride in pediatric intravenous therapy

Evidência
Severely ill children and newborns typically require a wide range of intravenous medications as part of specific therapies tailored to their developmental and growth characteristics.
Tatiany Calegari , Fernando Fonseca, Beatriz Alves, Glaucia da Veiga, Paulo César Rosa , Mavilde Pedreira, Maria Angélica Peterlini   +6 more
doaj  

Baicalein Loaded Polysorbate 80 Nanostructured Lipid Carriers Offered Enhanced Stability and In Vitro Drug Release

, 2016
Dinesh Kaushik
openalex   +2 more sources

Prediction of the changes in drug dissolution from an immediate-release tablet containing two active pharmaceutical ingredients using an accelerated stability assessment program (ASAPprime®) [PDF]

, 2016
Hanlin Li, David Nadig, Andrew Kuzmission, Christopher M. Riley   +3 more
openalex   +1 more source

Strength through diversity: how cancers thrive when clones cooperate

Molecular Oncology, EarlyView.
Intratumor heterogeneity can offer direct benefits to the tumor through cooperation between different clones. In this review, Kuiken et al. discuss existing evidence for clonal cooperativity to identify overarching principles, and highlight how novel technological developments could address remaining open questions.
Marije C. Kuiken, Maartje Witsen, Emile E. Voest, Krijn K. Dijkstra   +3 more
wiley   +1 more source

A stability-driven protocol for drug response interpretable prediction (staDRIP) [PDF]

, 2020
Xiao Li, Tiffany M. Tang, Xuewei Wang, Jean Pierre A. Kocher, Bin Yu   +4 more
openalex   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

Chemical profiling of the street cocktail drug ‘nyaope’ in South Africa using GC–MS I: Stability studies of components of ‘nyaope’ in organic solvents

, 2018
P.M. Mthembi, Ellen Mwenesongole, Michael Cole   +2 more
openalex   +1 more source

Next‐generation proteomics improves lung cancer risk prediction

Molecular Oncology, EarlyView.
This is one of very few studies that used prediagnostic blood samples from participants of two large population‐based cohorts. We identified, evaluated, and validated an innovative protein marker model that outperformed an established risk prediction model and criteria employed by low‐dose computed tomography in lung cancer screening trials.
Megha Bhardwaj, Clara Frick, Ben Schöttker, Bernd Holleczek, Hermann Brenner   +4 more
wiley   +1 more source

A VALIDATED STABILITY INDICATING RP-HPLC METHOD DEVELOPMENT FOR ANTI CANCER DRUG ENZALUTAMIDE IN BULK AND PHARMACEUTICALS

, 2019
B. Anjaneyulu Reddy, P. Radhakrishnanand, Md. Irshad Alam, P. Ravi Kiran   +3 more
openalex   +2 more sources

Stability-Indicating Spectrophotometric Methods for Determination of Milnacipran HCl and Duloxetine HCl in Bulk Drug and Pharmaceutical Formulations [PDF]

, 2019
Maha Abdel Ghany, Omar Y. Abdelaziz, Nermine V. Fares, Eman Eskander   +3 more
openalex   +1 more source