Results 171 to 180 of about 1,390,034 (354)

Ultrasonic-Assisted Degradation of Metformin from Pharmaceutical Effluent: Process Optimization via Response Surface Methodology [PDF]

Journal of Environmental Health and Sustainable Development
Introduction: Metformin, an extremely prescribed antidiabetic medication, is discharged with minimal or no processing and remains during the usual wastewater treatment procedures.
Shital P. Dehankar, Ratnadip R. Joshi
doaj  

dUTPase is essential in zebrafish development and possesses several single‐nucleotide variants with pronounced structural and functional consequences

FEBS Open Bio, EarlyView.
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon, Angéla Békesi, Latifa Kazzazy, Jázmin Mihály, Máté Varga, Beáta G. Vértessy, Kinga Nyíri   +6 more
wiley   +1 more source

Finding stability amidst the COVID‐19 pandemic: The impact of emergency temporary housing for people who use drugs [PDF]

, 2021
Eilish Scallan, Claire Bodkin, Jill Wiwcharuk, Tim O’Shea, Robin Lennox   +4 more
openalex   +1 more source

Anticancer sensitivities and biological characteristics of HCT116 cells resistant to the selective poly(ADP‐ribose) glycohydrolase inhibitor

FEBS Open Bio, EarlyView.
We analyzed alterations of PAR metabolism‐related proteins in PARG inhibitor‐resistant HCT116RPDD cells. Although PARG levels remained unchanged, HCT116RPDD cells exhibited reduced PARP1 and ARH3 expression and elevated PAR levels. Interestingly, HCT116RPDD cells exhibited slightly elevated intracellular NAD+/NADH and ATP levels. Our findings suggest a
Kaede Tsuda, Yoko Ogino, Akira Sato
wiley   +1 more source

Interaction of liposomes with bile salts investigated by asymmetric flow field-flow fractionation (AF4): A novel approach for stability assessment of oral drug carriers

, 2023
Mette Sloth Bohsen, Sofie Tandrup Tychsen, Ali Abdul Hussein Kadhim, Holger Grohganz, Alexander H. Treusch, Martin Brandl   +5 more
openalex   +2 more sources

Tumor‐stromal crosstalk and macrophage enrichment are associated with chemotherapy response in bladder cancer

FEBS Open Bio, EarlyView.
Chemoresistance in bladder cancer: Macrophage recruitment associated with CXCL1, CXCL5 and CXCL8 expression is characteristic of Gemcitabine/Cisplatin (Gem/Cis) Non‐Responder tumors (right side) while Responder tumors did not show substantial tumor‐stromal crosstalk (left side). All biological icons are attributed to Bioicons: carcinoma, cancerous‐cell‐
Sophie Leypold, Janik Riese, Lancelot Seillier, Mark Kühnel, Julia Pannhausen, Charlotte O. J. Fröhlich, Christian Martin, Peter Boor, Matthias Saar, Danny D. Jonigk, Nadine T. Gaisa, Michael Rose   +11 more
wiley   +1 more source

The role of lipid metabolism in neuronal senescence

FEBS Open Bio, EarlyView.
Disrupted lipid metabolism, through alterations in lipid species or lipid droplet accumulation, can drive neuronal senescence. However, lipid dyshomeostasis can also occur alongside neuronal senescence, further amplifying tissue damage. Delineating how lipid‐induced senescence emerges in neurons and glial cells, and how it contributes to ageing and ...
Dikaia Tsagkari, Eleftheria Panagiotidou, Nektarios Tavernarakis   +2 more
wiley   +1 more source

Photodynamic Inactivation Enhances Antibiotic Efficacy Without Affecting Drug Stability: Insights into Photosensitizer-Antibiotic Combination Therapies. [PDF]

Int J Mol Sci
Acosta RB, Durantini EN, Spesia MB.
europepmc   +1 more source

The Value of Drug Stability Studies and Their Publication. [PDF]

Can J Hosp Pharm, 2018
Brown G.
europepmc   +1 more source

Stability of Tandemly Repetitive Subelement PCR Patterns in Trichophyton rubrum over Serial Passaging and with Respect to Drug Pressure [PDF]

, 2012
Anita Hryncewicz‐Gwóźdź, Tomasz Jagielski, Katarzyna Kalinowska, Dagmara Baczyńska, Ewa Plomer-Niezgoda, Jacek Bielecki   +5 more
openalex   +1 more source