Results 201 to 210 of about 8,084,609 (393)

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon, Rui P. L. Neves, Nikolas H. Stoecklein, Sven‐Thorsten Liffers, Jens Siveke, Jan D. Kuhlmann, Pauline Wimberger, Paul Buderath, Rainer Kimmig, Sabine Kasimir‐Bauer   +9 more
wiley   +1 more source

Photodynamic Inactivation Enhances Antibiotic Efficacy Without Affecting Drug Stability: Insights into Photosensitizer-Antibiotic Combination Therapies. [PDF]

Int J Mol Sci
Acosta RB, Durantini EN, Spesia MB.
europepmc   +1 more source

The Value of Drug Stability Studies and Their Publication. [PDF]

Can J Hosp Pharm, 2018
Brown G.
europepmc   +1 more source

Facile one-pot green solvent synergized fluorescence reaction for determination of doxorubicin in presence of paclitaxel; co-administered drug, application to stability study and analysis in bulk, vial and biological fluids

, 2020
Sayed M. Derayea, Ramadan Ali, Ahmed Abdulhafez Hamad   +2 more
openalex   +1 more source

Methods To Enhance The Metabolic Stability Of Peptide Drugs

, 2021
Stanislava Ivanova, Silvia Mihaylova, Antoаneta Tsvetkova   +2 more
openalex   +2 more sources

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

In vitro skin permeation of mitragynine: Optimisation of antioxidants for enhanced drug stability and formulation performance. [PDF]

Drug Deliv Transl Res
Sim YS, Azizi J, Chear NJ, Yusof SR, Murugaiyah V, Teh SY, Goh CF.   +6 more
europepmc   +1 more source

The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity

Molecular Oncology, EarlyView.
Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli, Alessio Bevilacqua, Mathias Wenes, Denis Migliorini, Lars van der Veen, Sigrid S Skånland, Giusy Di Conza, Kjetil Taskén   +7 more
wiley   +1 more source

Development and Validation of a Stability-Indicating HPLC Method for Determination of Clorazepate Dipotassium and Its Main Impurities in Bulk Drug and Capsules

, 2015
Jankana Burana-osot, Chanokporn Sukonpan, Sooksri Ungboriboonpisal   +2 more
openalex   +2 more sources

Stability of Chosen Beta-Adrenolytic Drugs of Different Polarity in Basic Environment [PDF]

, 2008
Anna Kwiecień, Jan Krzek, Marek Ylewski
openalex   +1 more source