Results 291 to 300 of about 82,422 (345)

Synergistic activity of meropenem and sulbactam against carbapenem-resistant Acinetobacter baumannii.

Indian J Pharmacol
Amruthavarshini I, Rajshekar D, Rao R, Harish AM.   +3 more
europepmc   +1 more source

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Drug Resistance and Drug Synergism

2014
Richard B Silverman
exaly   +2 more sources

Drug Synergism

Science, 1958
exaly   +4 more sources

Drug synergism as a basis for rational neuroprotection

Zhurnal nevrologii i psikhiatrii im. S.S. Korsakova, 2022
Optimization of the choice of neuroprotective therapy regimens in patients with CVD, taking into account the synergism of drug interactions, is basic in real clinical practice. Unfortunately, in modern pharmacology there is no unified way to establish the synergistic spectrum of action of drugs, which would allow systematic investigation of the effects
M.V. Putilina, N.V. Teplova
openaire   +2 more sources

Teratogenic Risks of Drug Synergism

Nature, 1964
IT is well known that the effectiveness of teratogens, measured either in incidence or in severity of resulting malformations, is frequently modified, in a plus or minus direction, by unrelated external conditions. The mechanisms by which these modifying agencies operate are largely unknown.
W, LANDAUER, E M, CLARK
openaire   +2 more sources

Communicating Synergism in Drug Combination Studies

Arzneimittelforschung, 2011
Isobolograms are used to identify synergistic effects of drugs given in combination. However, the traditional isobologram provides only a qualitative determination of synergism. The present report describes two procedures for quantifying the synergistic actions of drugs based on isobolographic plots.
J, Brodkin, H E, Shannon
openaire   +2 more sources

Synergism between Histamine, Antihistamines, and Hypnotic Drugs†

Journal of the American Pharmaceutical Association (Scientific ed.), 1952
The synergism between antihistamines and the barbiturate Evipal was studied in mice. Similar synergism was found between histamine and barbiturates and between antihistamines and ether. The possible clinical usefulness of these findings is discussed. Thephorin, in mice, shows a synergistic effect with barbiturates or ether similar to that of Benadryl ...
J L, AMBRUS, C M, AMBRUS, C A, LEONARD, C E, MOSER, J W E, HARRISSON   +4 more
openaire   +2 more sources

A Fatality Due to Drug Synergism

Medicine, Science and the Law, 1982
Thioridazine is a phenothiazine tranquillizer with specificity for psychotherapeutic action. It is well tolerated but will induce changes in myocardial repolarization which are further aggravated in the presence of low blood potassium levels. Fatalities due to overdosage of thioridazine are rare and those associated with therapeutic dosage and cross ...
openaire   +2 more sources

Drug Synergism: Its Detection and Applications

The Journal of Pharmacology and Experimental Therapeutics, 2001
Two drugs that produce overtly similar effects will sometimes produce exaggerated or diminished effects when used concurrently. A quantitative assessment is necessary to distinguish these cases from simply additive action. This distinction is based on the classic pharmacologic definition of additivity that, briefly stated, means that each constituent ...
openaire   +2 more sources