Results 241 to 250 of about 10,148,101 (391)

Drug Therapy in Infants [PDF]

, 1985
S. McKenzie
openalex   +1 more source

Targeting of PTP4A3 overexpression sensitises HGSOC cells towards chemotherapeutic drugs

Molecular Oncology, EarlyView.
In HGSOC with normal KRAS expression, high PTP4A3 expression regulates autophagy activation. Conversely, in HGSOC with high KRAS expression, KRAS dictates autophagy control, and PTP4A3 is not required. When high PTP4A3 expression is inhibited, HGSOC cells are preferentially sensitised towards DNA‐damaging agents.
Ana López‐Garza, David James, Emma Creagh, James T. Murray   +3 more
wiley   +1 more source

Current status of drug therapy for chronic hepatitis B. [PDF]

World J Gastroenterol
Jiang C, Zhang ZH, Li JX.
europepmc   +1 more source

Percutaneous Absorption: Controlled Drug Delivery For Topical or Systemic Therapy

, 1976
Jane E. Shaw, Saravan Kumar Chandrasekaran, P. S. Campbell   +2 more
openalex   +1 more source

Drug Points: Buprenorphine: dangerous drug or overlooked therapy? [PDF]

, 1986
J R Robertson, A B Bucknall
openalex   +1 more source

Olaparib synergy screen reveals Exemestane induces replication stress in triple‐negative breast cancer

Molecular Oncology, EarlyView.
Screening 166 FDA‐approved anticancer drugs identifies the aromatase inhibitor Exemestane as a synergistic partner of PARP inhibitor Olaparib in BRCA‐proficient triple‐negative breast cancer. Exemestane induces ROS‐mediated replication stress, enhancing DNA damage and apoptosis alongside Olaparib.
Nur Aininie Yusoh, Liping Su, Suet Lin Chia, Xiaohe Tian, Haslina Ahmad, Martin R. Gill   +5 more
wiley   +1 more source

The Timeliness of Drug Therapy in Colorectal and Prostate Cancer in Antigua and Barbuda: The Role of Disease Stage. [PDF]

Healthcare (Basel)
Bovell AAN, Ncayiyana J, Ginindza TG.
europepmc   +1 more source

Inhibition of thromboxane formation in vivo and ex vivo: implications for therapy with platelet inhibitory drugs [PDF]

, 1987
IA Reilly, GA FitzGerald
openalex   +1 more source

Nicotinamide N‐methyltransferase promotes drug resistance in lung cancer, as revealed by nascent proteomic profiling

Molecular Oncology, EarlyView.
AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou, Zhen Wang, Fei Yang, Xiao Han, Lei Li, Huadong Liu   +5 more
wiley   +1 more source

Appraisal of guidelines and variations in recommendations on drug therapy for invasive aspergillosis prevention and treatment. [PDF]

Front Pharmacol
Wang J, Sun J, Yang DW, Wang HS, Meng W, Li HY.   +5 more
europepmc   +1 more source