Results 281 to 290 of about 4,734,823 (307)

Tolerance to Drug Discriminative Stimuli

1989
Repeated encounters with a psychoactive drug create a potent opportunity for the drug to play a critical role in the development and expression of behavior. Repeated exposure can provide the behavioral conditions necessary for psychoactive drugs to function as conditional, reinforcing, or discriminative stimuli, controlling the acquisition and ...
Alice M. Young, Christine A. Sannerud
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Tolerance to anorectic drugs: Pharmacological or artifactual

Pharmacology Biochemistry and Behavior, 1981
Abstract The results of three studies are presented which demonstrate that the anorexia produced by amphetamine and fenfluramine is secondary to a direct weight suppressing effect of these drugs. Furthermore, these data strongly suggest that the decreasing weight loss and the return to normal appetite that occurs with repeated drug usage is not due ...
David A. Levitsky, Janet Lupoli, Barbara J. Strupp   +2 more
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Cholinergic drug interactions and heat tolerance

Life Sciences, 1994
Acute, subchronic and chronic exposures to cholinergic compounds may result in differing effects. The efficacy of pyridostigmine bromide (PY) prophylaxis against organophosphorus poisoning depends on post exposure atropine (AT) administration. AT induces a dose-dependent increase in rate of rise of core temperature in heat exposed humans and rats.
John F. Glenn, Daniel K. Navara, Candace B. Matthew, Wilbert D. Bowers   +3 more
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The relation between drug exposure and tolerance: contingent drug tolerance reexamined

1994
The finding that the performance of a response during periods of drug exposure facilitates the development of tolerance to the effects of the drug on that response is commonly referred to as contingent drug tolerance. Contingent tolerance is typically demonstrated in before-and-after design experiments.
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Drug tolerance, persister cells and drug discovery.

2012
Abstract This chapter discusses the clinical importance of drug tolerance mechanisms and persister cells, and their reletionship to efforts on new antimicrobial drug discovery. Important mechanisms related to biofilm formation in persister cells are also described.
K. Lewis, Eleftherios Mylonakis, A. Tegos   +2 more
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Tolerance to drug stimulus control

Drug Development Research, 1990
AbstractA psychoactive drug can acquire discriminative stimulus control of behavior through differential reinforcement processes. Development of tolerance to drug stimulus control reflects a dynamic interaction of conditioning and pharmacodynamic processes.
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Nonpharmacological bases of drug tolerance and dependence

Journal of Psychosomatic Research, 1982
Abstract Research demonstrating a role of nonpharmacological factors in drug tolerance is reviewed. Other research documenting a role of similar nonpharmacological factors in post-treatment relapse is reviewed, and it is suggested that there may be a common mechanism involved in nonpharmacological influences on tolerance and relapse.
Shepard Siegel, Riley E. Hinson
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Drug resistance or tolerance in schistosomes?

Trends in Parasitology, 2002
In their interesting article on low cure rates of Schistosoma mansoni in Senegal, A. Dano-Appiah and S.J. De Vlas [1xInterpreting low praziquantel cure rates of Schistosoma mansoni infection in Senegal. Danso-Appiah, A. and De Vlas, S.J. Trends Parasitol. 2002; 18: 125–129Abstract | Full Text | Full Text PDF | PubMed | Scopus (103)See all References][1]
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Tolerance to Anticonvulsant Drugs

Acta Pharmacologica et Toxicologica, 1965
H.-H. Frey, Elsemarie Kampmann
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Drugs and glucose tolerance

Adverse Drug Reaction Bulletin, 1986
Roy Taylor, Steven J Hurel
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