Monitoring Endocytosis of Integral Membrane Proteins Using Western Blot-Based Detection of Biotinylated Antibody Uptake. [PDF]
Bio ProtocGraninger A, Satpute-Krishnan P.
europepmc +1 more source
Advanced Science, EarlyView.This study introduces MnSTF, a soft‐drug‐inspired nanoadjuvant that overcomes the systemic toxicity of STING agonists. Through Mn2+ coordination with an ENPP1 inhibitor, it enables safe cGAS‐STING activation, remodels the tumor immune microenvironment, and synergizes with radiotherapy or vaccines to elicit robust antitumor immunity.
Guangfei Sun +8 more
wiley +1 more source
The 'slow-burn effect' of human trafficking following disaster. [PDF]
DisastersWeeks C.
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Targeting the Dynamics Between TAMs and CAR‐T Cells in Solid Tumor Therapies
Advanced Science, EarlyView.This review highlights the critical role of tumor‐associated macrophages (TAMs) in affecting CAR‐T cell therapy effectiveness in solid tumors. TAMs contribute to immune suppression through cytokine secretion, immune checkpoint activation, and metabolic reprogramming, leading to CAR‐T cell exhaustion and reduced efficacy. The article explores strategies
Xiang Zhang +7 more
wiley +1 more source
Reply to Rattanapitoon et al., "Reconsidering the <i>Toxoplasma gondii</i> interactome: opportunities beyond crosslinking mass spectrometry". [PDF]
mBioTomita T +5 more
europepmc +1 more source
Editorial: Finding new hope in old treatments: repurposing immunotherapy in transplantation. [PDF]
Front ImmunolNian Y, Iske J, Yuan X.
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Failure of lysosomal acidification and endomembrane network in neurodegeneration. [PDF]
Exp Mol MedKim SH, Cho YS, Jung YK.
europepmc +1 more source
Cepharanthine inhibits enterovirus entry by endolysosomal deacidification and exhibits protective activity <i>in vivo</i>. [PDF]
Antimicrob Agents ChemotherWeng T-C, Hsu B-Y, Kung S-H.
europepmc +1 more source
Modelling Lowe syndrome and Dent-2 disease using zebrafish. [PDF]
Front Cell Dev BiolLowe M.
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