Results 31 to 40 of about 12,434 (265)

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

open access: yesFEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi   +5 more
wiley   +1 more source

Assessments of health workers on the implementation of the safety system in the use of medications - Apreciaciones de trabajadores de la salud sobre la implementación del sistema de seguridad en la utilización de medicamentos

open access: yesUniversidad y Salud, 2017
Introduction: Errors in medication is one of the most frequent adverse events in most of the countries in Latin America, which has led to promote a system for its identification and reduction in health institutions.
Aleyda Restrepo Vásquez   +1 more
doaj   +1 more source

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Characteristics and Biological Activities of a Novel Polysaccharide R1 Isolated from Rubus chingii Hu

open access: yesFoods
Raspberry (Rubus chingii Hu) is a Chinese herb that is rich in nutrients and has anti-inflammatory, antibacterial, antioxidant, anti-allergic, hypoglycemic, and other effects. A water-soluble polysaccharide was extracted from raspberry by using hot water
Zhier Lin   +5 more
doaj   +1 more source

Drug Prescribing Practices in Dental Care Patients at a Dental and Maxillofacial Surgery Clinic in Oman

open access: yesOman Medical Journal, 2020
Objectives: We sought to assess medications prescribed to patients attending the Dental and Maxillofacial Surgery (DMS) clinic at Sultan Qaboos University Hospital (SQUH), Oman. Methods: This was a retrospective cross-sectional study covering a six-month
Mohammed S. Al-Rashdi   +2 more
doaj   +1 more source

Switching TNFα inhibitors: Patterns and determinants

open access: yesPharmacology Research & Perspectives, 2021
The aim of this study was to assess switching patterns and determinants for switching in patients initiating TNFα inhibitor (TNFα‐i) treatment. Patients were included who started TNFα‐i treatment between July 1, 2012 and December 31, 2017, from three ...
Rosanne W. Meijboom   +8 more
doaj   +1 more source

POPPY II Cohort Profile– a population-based linked cohort examining the patterns and outcomes of prescription opioid use in NSW, Australia, 2003-2018.

open access: yesInternational Journal of Population Data Science, 2022
Objectives Although opioid prescribing and harms have increased in Australia, there is a lack of population-level evidence about the drivers of long-term opioid use, dependence and other harms. This study aims to profile the POPPY II cohort, with respect
Natasa Gisev   +11 more
doaj   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

open access: yesFEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Utility of Treatment Pattern Analysis Using a Common Data Model: A Scoping Review [PDF]

open access: yesHealthcare Informatics Research
Objectives We aimed to derive observational research evidence on treatment patterns through a scoping review of common data model (CDM)-based publications.
Eun-Gee Park   +4 more
doaj   +1 more source

Consumption and Lack of Access to Medicines and Associated Factors in the Brazilian Amazon: A Cross-Sectional Study, 2019

open access: yesFrontiers in Pharmacology, 2020
ObjectiveWe aimed to investigate the consumption and lack of access to medicines in the adult population of Manaus, Amazonas.MethodsA population-based study was conducted in Manaus in 2019.
Gustavo Magno Baldin Tiguman   +2 more
doaj   +1 more source

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