Results 231 to 240 of about 16,766,351 (298)

Secondary Prevention Bundle for Drug-Related Problems in an Integrated Healthcare Setting: A Pragmatic Observational Implementation-Effectiveness Study. [PDF]

Pharmacy (Basel)
Fernández-Morató J, Ruiz-Ramos J, Fuster-Barrera M, Antón-López A, Romero EO, Plaza-Ruiz A, Roure-I-Nuez C.   +6 more
europepmc   +1 more source

From patient advocacy to patient‐driven research: Building active partnerships beginning at the bench to reach the bedside

FEBS Open Bio, EarlyView.
Research is strongest when conducted alongside patients, not just about them. Patient research organizations help integrate patient perspectives into research priorities, study design, and scientific meetings, leading to meaningful patient outcomes and development of relevant therapies.
Jenica H. Kakadia, Rachel Heilmann, Maximiliano Barrientos, Laura MacNeill, Ingrid Vallee, Sarah K. Schultz, Patrick O'Donoghue, Angelica A. Moresco, Victoria M. Siu, Ilka U. Heinemann   +9 more
wiley   +1 more source

Avidin is evolutionarily conserved in fish but dispensable for development and resistance against Streptococcus agalactiae in zebrafish

FEBS Open Bio, EarlyView.
The presence of biotin‐binding avidin proteins in fish and their biological significance are poorly characterized. We cataloged fish avidins and demonstrate that they are widely present and evolutionarily conserved. We created avd knockout zebrafish and show that zebavidin is dispensable for development and that resistance of avd knockout embryos in ...
Anni K. Saralahti, Markus J. T. Ojanen, Mataleena Parikka, Otto Kauko, Mika Rämet, Vesa P. Hytönen   +5 more
wiley   +1 more source

Temporal Drivers of Opioid-Related ED Visits: An Ensemble Machine Learning Study With Consensus-Based Feature Attribution. [PDF]

Clin Transl Sci
Dixon RJ, Price ET.
europepmc   +1 more source

GelMA‐based 3D spheroids recapitulate transcriptomic and functional hallmarks of myeloid sarcoma

FEBS Open Bio, EarlyView.
GelMA 5% hydrogels support the formation of myeloid leukemia spheroids that recapitulate MS‐specific features, including G1 arrest, apoptosis, and ECM‐driven transcriptomic reprogramming. The 3D model mimicked soft‐tissue‐like stiffness and oxygen conditions, and transcriptomic convergence with primary MS samples confirmed its utility as a preclinical ...
Nicolas Germain, Elise Buret, Le Hoang Thanh Nguyen, Marion Cocheteux, Nicolas Touya, Mélanie Dhayer, Romain Dubois, Frank Lafont, Sebastien Janel, Patrice Maboudou, Steve Lancel, Philippe Marchetti   +11 more
wiley   +1 more source

Medicare Part D formulary coverage of SGLT2 inhibitors across cardiovascular-kidney-metabolic indications, 2019-2026. [PDF]

Endocrine
Jain V, McCoy RG.
europepmc   +1 more source

Salmonella enterica serovar typhi limits the potency of typhoid toxin and ADP‐ribosylating toxin AB to establish a persistent infection

FEBS Open Bio, EarlyView.
The two catalytic subunits of typhoid toxin dissociate from the holotoxin in the ER of an intoxicated cell, but only CdtB exits the ER to generate immunosuppressive effects. PltA is retained in the ER and sequestered from its cytosolic target, thus allowing the anti‐inflammatory effects of CdtB to promote intestinal colonization.
Maria C. Zabala‐Rodriguez, Juliette K. Tinker, Teresa Frisan, Taj Azarian, Ken Teter   +4 more
wiley   +1 more source

A Scoping Review of Cost Analyses in Endoscopic Sinus Surgery: Economic Trends, Cost Drivers, and Methodological Gaps. [PDF]

Laryngoscope Investig Otolaryngol
Rana N, Swanson D, Tsao E, Dorris CS, Wasan R, Spielman D.   +5 more
europepmc   +1 more source

Semaglutide and Panic Attacks: Active-Comparator Disproportionality Analysis, Temporal Assessment of Notoriety Bias and Evidence Triangulation in Post-Marketing Pharmacovigilance. [PDF]

Pharmacoepidemiol Drug Saf
Melamed B, Parsi-Zahabi M, Omrani MA, Baskaran BS, Eddin LE, Kermanshahi N, Chalabianloo N, Muanda FT.   +7 more
europepmc   +1 more source

The perils and consequences of payer step editing ("Step Therapy") in US medical oncology: evidence, case examples, and policy remedies. [PDF]

Oncologist
Gordan LN, Boykin K, Reff M, Chadwick P, Mehring K, Cox A, Wenk D, Fink M, Eaves J, Ciarrocchi R.   +9 more
europepmc   +1 more source