Results 101 to 110 of about 82,737 (314)

Current trends in drug metabolism and pharmacokinetics. [PDF]

, 2019
Pharmacokinetics (PK) is the study of the absorption, distribution, metabolism, and excretion (ADME) processes of a drug. Understanding PK properties is essential for drug development and precision medication.
Abduljalil, Aghazadeh-Habashi, Aigrain, Aitman, Al Za'abi, Alegre, Alnaqeeb, Aspromonte, Babiskin, Baert, Bakke, Barnett, Bhattacharyya, Cang, Cannady, Cao, Cao, Capecchi, Chen, Chen, Chen, Chen, Chen, Chen, Chen, Cheng, Cheng, Crawford, Currie, De Lange, Dean, Deng, Di Paolo, Dietrich, Diliberto, Dluzen, Dowling, Dragin, Dreisbach, Duan, Edeogu, Edginton, El-Arabey, El-Kadi, EMA, Eum, Falany, Fang, FDA, Feng, Feng, Feng, Ferri, Fleming, Foti, Fox, Freedman, Frye, Fukami, Gaj, Gan, Gao, Gao, Gao, Gao, Gao, Ge, Genovese, Gingell, Gingell, Gong, Graham, Gufford, Guo, Guo, Guo, Guévin, Han, Harrison, Hartz, Hasegawa, He, He, He, He, He, Ho, Ho, Hou, Hsu, Hsueh, Hu, Hu, Hu, Huo, Hwang, Ito, Jacob, Jeong, Jeong, Jia, Jian, Jiang, Jiang, Jiang, Jiang, Jilek, Jilek, Johnson, Jorga, Jung, Kaivosaari, Kalthoff, Kaminsky, Kannan, Karibe, Kesisoglou, Kim, Kim, Knights, Kong, Kota, Kumar, Kurokawa, Lai, Lan, Lanchote, Lee, Lehouritis, Li, Li, Li, Li, Li, Li, Li, Li, Li, Li, Li, Liang, Lin, Liu, Liu, Liu, Liu, Liu, Liu, Liu, Liu, Liu, Liu, Liu, Liu, Lopes-Rodrigues, Lu, Lu, Lu, Löfgren, Mano, Marchitti, Margolskee, Martin, Matsson, Mattick, Mazerska, Mei, Mencia, Meng, Min, Mitra, Miyajima, Müller, Nair, Nakano, Nakano, Nakano, Nebert, Nguyen, Niederalt, Nieto Montesinos, Niu, Notenboom, Nozaki, Ohtsuki, Ono, Oostendorp, Pan, Pan, Papageorgiou, Papageorgiou, Park, Pea, Pedersen, Pelkonen, Pellegrino, Pettersson Bergstrand, Qi, Qin, Qiu, Qiu, Raaska, Rives, Riviere, Roberts, Robey, Rocha, Rose, Routy, Rowland, Ruwali, Saini, Satoh, Savage, Scheer, Scheer, Schlender, Schmitt, Schneider, Seitz, Showande, Shu, Shu, Shu, Shugarts, Siu, Song, Staudinger, Strong, Suarez-Sharp, Suh, Suiko, Sukkummee, Sun, Sun, Sutliff, Takeda, Tan, Tan, Tao, Tatsumi, Teorell, Tsai, Tsang, Tsuchiya, Tsume, Tu, Ulldemolins, van Waterschoot, von Richter, Vugmeyster, Vuppugalla, Wagner, Wagner, Wagner, Wang, Wang, Wang, Wang, Wang, Wang, Wang, Wang, Wang, Wang, Wang, Wassenaar, Watanabe, Wei, Wijayakumara, Wilkinson, Wong, Wu, Xia, Xie, Xie, Xu, Xu, Xu, Xu, Xu, Xue, Yamagata, Yamaguchi, Yan, Yang, Yang, Yang, Ye, Yellepeddi, Yi, Yi, Yigitaslan, Yim, Yin, Yoshida, Yoshida, Yoshimi, Yu, Yu, Yu, Yu, Yu, Yu, Yu, Zakeri-Milani, Zanger, Zeng, Zeng, Zhai, Zhang, Zhang, Zhang, Zhang, Zhang, Zhang, Zhang, Zhang, Zhang, Zhao, Zhao, Zhao, Zhao, Zhou, Zhou, Zhou, Zhou, Zhou, Zhu, Zhu, Zhu, Zhuang, Zimmermann   +332 more
core   +1 more source

Deciphering the catalytic and pharmacological mechanisms of Coptis chinensis herbzymes to renovate intestinal microenvironment for colitis alleviation

BMEMat, EarlyView.
The synthesized CCzymes possess both antioxidant enzyme activity and pharmacological properties inherent to Coptis chinensis. By their antioxidant enzyme activity, CCzymes can attenuate oxidative stress within the inflammatory region of ulcerative colitis (UC), while their pharmacological activity acts on macrophage polarization and the intestinal ...
Zhichao Deng, Can Li, Yujie Zhang, Yuanyuan Zhu, Chenxi Xu, Bowen Gao, Mingxin Zhang, Martina H. Stenzel, Kelong Fan, Mingzhen Zhang, Yanyan Jiang   +10 more
wiley   +1 more source

Clinical management of children with tic disorder: insights from therapeutic visits in China—a real-world study

Frontiers in Pediatrics
ObjectiveThis retrospective study aims to investigate the treatment of tic disorder (TD) in Dongfang Hospital affiliated with Beijing University of Chinese Medicine, explore its underlying mechanism, and provide valuable insights for future research and ...
Jing Wang, Jing Wang, Changyong Luo, Zhendong Wang, Zhendong Wang, Tiegang Liu, Chen Bai, Yang Wang, Yuanshuo Tian, Qianqian Li, Zhaoxin Wang, Liqun Wu, Sumei Wang, Xiaohong Gu   +13 more
doaj   +1 more source

A Natural Resource‐Based View of Circular Economy Practices in the Pharmaceutical Industry

Business Strategy and the Environment, EarlyView.
ABSTRACT Pharmaceutical industry is facing escalating environmental sustainability issues including gaseous emissions, waste generation, and excessive consumption of energy and non‐renewable materials. Nevertheless, the adoption of sustainable business models such as the circular economy (CE) is still in its infancy in this sector due to complex ...
Amna Farrukh, Muhammad Sohaib Sajjad
wiley   +1 more source

Nephroprotective Potential of Olea europaea Leaf Extract Against Combined Noise and Toluene‐Induced Oxidative and Histopathological Renal Injuries in Wistar Rats

Chemistry &Biodiversity, EarlyView.
ABSTRACT Noise and toluene are environmental stressors that induce oxidative stress and inflammation, contributing to renal dysfunction. This study evaluated the protective effects of Olea europaea leaf extract (OeLE; 40 mg/kg/day) against combined noise‐ and toluene‐induced nephrotoxicity in Wistar rats.
Takoua Ben Attia, Mabrouk Horchani, Mariem Salhi, Zeineb Dhifallah, Meriem Ksentini, Hichem Ben Jannet, Abada Mhamdi   +6 more
wiley   +1 more source

The regulation of intestinal microbiota and the intervention of Chinese herbal medicine in the treatment of ulcerative colitis

Pharmacological Research - Modern Chinese Medicine
Background: The incidence of Ulcerative colitis (UC), a key form of inflammatory bowel disease (IBD) affecting the rectum and colon, is increasing globally.
Wang Haiou, Li Jinyou, Huang Wenkang, Ye Yiping, Gao Lijuan   +4 more
doaj   +1 more source

INSIGHTS INTO THE MONOMERS AND SINGLE DRUGS OF CHINESE HERBAL MEDICINE ON MYOCARDIAL PRESERVATION

African Journal of Traditional, Complementary and Alternative Medicines, 2011
Chinese herbal drugs have been proved to be effective agents in myocardial protection by preventing ischemia-reperfusion injury. The underlying mechanisms as to how these agents work were however poorly elucidated. Studies on the monomers or on the single drugs have highlighted the possible rationales, leading to a better understanding of the ...
Yuan, Shi-Min, Jing, Hua
openaire   +4 more sources

'Experts', 'partners' and 'fools': exploring agency in HIV treatment seeking among African migrants in London [PDF]

, 2010
In an attempt to promote patient agency and foster more egalitarian relationships between patients and doctors, discourse concerning health and wellbeing in the UK has increasingly centred around the notion of informed and 'expert' patients who are able ...
Ariko, Broom, Bury, Cant, Charles, Cohen, Coulter, Davis, Del Casino, Department of Health, Department of Health, Doyal, Doyal, Felicity Thomas, Fox, Frank, Garro, Gold, Green, Green, Helman, Horne, Imrie, Jane Anderson, Johnson, Kesby, Keshet, Kitchen, Kleinman, Kremer, Laurance, Littlewood, Lupton, Mariandina Nutritional Health Products, Mattingly, Mills, Mills, Muir Gray, Niehaus, Ong, Owen-Smith, Pawluch, Peltzer, Persson, Peter Aggleton, Reynolds, Rosengarten, Schoepf, Schumaker, Tang, van der Geest, Whelan, Wilson, Wong, Yallop   +54 more
core   +2 more sources

A Phase 1 Open‐Label Study to Evaluate the Pharmacokinetics, Safety, and Tolerability of a Single Intranasal Dose of Zavegepant in Healthy Chinese Adults

Clinical Pharmacology in Drug Development, EarlyView.
Abstract Zavegepant is the only calcitonin gene‐related peptide antagonist approved as a nasal spray in the United States for acute treatment of migraine in adults with or without aura. This Phase 1, open‐label study evaluated the pharmacokinetics, safety, and tolerability of a single intranasal dose of zavegepant 10 mg in 12 healthy Chinese adults ...
Qiong Wei, Jufang Wu, Yangyi Dai, Jiaye Lin, Beikang Ge, Yanhui Sun, Jing Zhang, Jing Wang, Chen Li, Ding Ding, Jing Liu, Mohamed H. Shahin   +11 more
wiley   +1 more source

Global Ethics and Nanotechnology: A Comparison of the Nanoethics Environments of the EU and China [PDF]

, 2012
The following article offers a brief overview of current nanotechnology policy, regulation and ethics in Europe and The People’s Republic of China with the intent of noting (dis)similarities in approach, before focusing on the involvement of the public ...
A Anderson, A Mnyusiwalla, AA Shvedova, AG Spagnolo, B McKibben, B Trouiller, C Buzea, D Bennett-Woods, D Evans, E Oberdorster, F Zhao, G Gaskell, G Kirsten, H Widdows, HB Friedman, J Schummer, J-H Hsaio, K Choi, K Finkler, K Pandza, L Jia, L Tang, M Oud, R Andorno, R Doubleday, RP Suttmeier, RW Berne, S Jasanoff, S Wood, Sally Dalton-Brown, SH Li, W Adams, W Hu   +32 more
core   +1 more source