Summary This second part of the S3 guideline on the diagnosis and treatment of alopecia areata (AA), presents key recommendations on topical and systemic therapy, quality of life and support services. The first part of the guideline, published separately, covers the definition and content of epidemiology and diagnosis as well as comorbidities, risk and
Ulrike Blume‐Peytavi +13 more
wiley +1 more source
OptiSyn: an interpretable, multi-omics-driven graph convolutional network framework for synergy-oriented drug combination design in disease treatment. [PDF]
Shi Y +9 more
europepmc +1 more source
Mechanisms underlying the protective effects of San‐Bai decoction against UV radiation on the skin
Combining conventional differential expression analysis with differential network analysis offers a promising strategy to uncover the mechanistic basis of the holistic benefits provided by herbal blends. Our findings demonstrated that San‐Bai decoction modulates multiple pathways—not only those related to skin pigmentation, such as ET‐1 signalling, but
Rui Zhang +7 more
wiley +1 more source
Anticipated Stigma in Nursing: A Concept Analysis Informed by Cannabis Use Disclosure
ABSTRACT Aim To clarify the concept of anticipated stigma and examine its relevance to cannabis use disclosure in nursing using an evolutionary concept analysis approach. Design Concept analysis guided by Rodgers and Knafl's evolutionary method. Data Sources An interdisciplinary purposive literature review was conducted using empirical and theoretical ...
Daniel D. King
wiley +1 more source
Can <i>Patrinia villosa</i> water extract be taken during FOLFOX treatment in colon cancer? - evidences from a proof-of-concept preclinical study. [PDF]
Yue GG +10 more
europepmc +1 more source
Abscisic acid signaling homeostasis is essential for seed storability. The molecular chaperone OsCPN10a enhances rice seed storability by forming a trimeric chaperone complex with OsCPN20‐OsHSP60‐3B that attenuates abscisic acid signaling via direct interaction with OsPYL10‐OsABIL1, thereby maintaining starch integrity and offering a promising target ...
Sufeng Liao +13 more
wiley +1 more source
Research progress on mechanisms and applications of Chinese herbal pairs in treating hyperplasia of mammary gland. [PDF]
Liu L +5 more
europepmc +1 more source
ABSTRACT Heavy metals have been documented in dietary supplements for people and animals. Cadmium, selenium, lead, and mercury are of particular concern. Our objective was to determine the concentrations of five essential minerals and 12 heavy metals in 70 canine and feline dietary supplements, and to evaluate potential toxicity risks.
Taryn K. Pestalozzi +2 more
wiley +1 more source
Analysis of risk factors for herb-induced liver injury: a retrospective study from China. [PDF]
Wang P +10 more
europepmc +1 more source
Systemic, Lifestyle and Environmental Modifying Factors in the Pathogenesis of Periodontitis
A variety of impacting factors in the pathogenesis of periodontitis exist, including systemic, lifestyle, and environmental factors. This review highlights the manifold mechanistic aspects of the link between the pathogenesis of periodontitis, addressing these numerous factors to supplement the long‐standing knowledge of the progression of the disease.
Groeger Sabine Elisabeth +5 more
wiley +1 more source

