Results 191 to 200 of about 181,905 (281)

ElixirSeeker: A Machine Learning Framework Utilizing Fusion Molecular Fingerprints for the Discovery of Lifespan‐Extending Compounds

open access: yesAging Cell, EarlyView.
ElixirSeeker is a machine learning architecture based on a phenotype‐driven drug discovery approach to screen lifespan‐extending compounds. By integrating molecular fingerprints, ElixirSeeker could maximize feature capture of lifespan‐extending compounds.
Yan Pan   +15 more
wiley   +1 more source

Early identification of the use of potent benzylbenzimidazoles (nitazenes) through wastewater analysis: Two years of data from 22 countries

open access: yesAddiction, EarlyView.
Abstract Background and Aims The use of new synthetic opioids, such as the highly potent 2‐benzylbenzimidazoles (i.e. nitazene) drugs, is a global health concern because of their increased risk of fatal overdose. In the early 2020s, nitazene analogues were linked to significant numbers of overdoses in the United States.
Richard Bade   +5 more
wiley   +1 more source

Prevalence and impact of vasomotor symptoms associated with menopause among Nordic women: Subgroup analysis from an international cross‐sectional survey

open access: yesActa Obstetricia et Gynecologica Scandinavica, EarlyView.
This international cross‐sectional survey of women aged 40–65 years from Nordic Europe adds to global findings demonstrating that moderate to severe vasomotor symptoms are prevalent and impair quality of life, sleep, work productivity, and daily activities. Abstract Introduction The objectives of this study were to evaluate the prevalence and impact of
Angelica Lindén Hirschberg   +6 more
wiley   +1 more source

Treatment Patterns for Incident Bipolar Disorder Among Nonrefugee Immigrants, Refugees, Second‐Generation Immigrants, and Host Population in Sweden

open access: yesBipolar Disorders, EarlyView.
ABSTRACT Background Deviations in treatment practices toward immigrant groups compared to host populations are common in mental disorders but unknown in bipolar disorder (BD). We aim to close this research gap by analyzing age‐stratified use patterns of antidepressants, mood stabilizers, and antipsychotics following an incident diagnosis of BD in ...
Alexander Kautzky   +8 more
wiley   +1 more source

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