Results 201 to 210 of about 3,396,597 (298)

Pharmacographia. A history of the principal drugs of vegetable origin, met with in Great Britain and British India. By Friedrich A. Flückiger, Phil. Dr., Professor in the University of Strassburg, and Daniel Hanbury, F. R. S., Fellow of the Linnean and Chemical Societies of London. Second edition. Macmillan and Co. 1879. 803 S. in Octav. [PDF]

, 1880
Th. Husemann
openalex   +1 more source

Nicotinamide N‐methyltransferase promotes drug resistance in lung cancer, as revealed by nascent proteomic profiling

Molecular Oncology, EarlyView.
AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou, Zhen Wang, Fei Yang, Xiao Han, Lei Li, Huadong Liu   +5 more
wiley   +1 more source

Research and development investments for biologics independently developed by US biotechnology startups, 2017-2023. [PDF]

Health Aff Sch
Odouard IC, Kang SY, Mo J, Anderson GF, Alexander GC.   +4 more
europepmc   +1 more source

Methyl-fluoro-phosphorylcholines. Two Synthetic Cholinergic Drugs and Their Tertiary Homologues. [PDF]

, 1957
L.‐E. Tammelin, Bertil Sjöberg, M. Moutschen-Dahmen, B. Noer, L. Reio   +4 more
openalex   +1 more source

Decrypting cancer's spatial code: from single cells to tissue niches

Molecular Oncology, EarlyView.
Spatial transcriptomics maps gene activity across tissues, offering powerful insights into how cancer cells are organised, switch states and interact with their surroundings. This review outlines emerging computational, artificial intelligence (AI) and geospatial approaches to define cell states, uncover tumour niches and integrate spatial data with ...
Cenk Celik, Shi Pan, Eloise Withnell, Hou Wang Lam, Maria Secrier   +4 more
wiley   +1 more source

Recent Research Advances in HER2-Positive Breast Cancer Concerning Targeted Therapy Drugs. [PDF]

Molecules
Li J, Li X, Fu R, Fang Y, Zhang C, Ma B, Ding Y, Shi C, Zhou Q.   +8 more
europepmc   +1 more source

Microglia limit brain tumor development by restricting tumor cell proliferation and inducing T‐cell immunity

Molecular Oncology, EarlyView.
Microglia (BV2) and IL‐4‐treated BMDMs promote astrocytoma clustering and inhibit tumor growth, not shown in other macrophage cells. In vivo, microglial co‐implantation enhances CD8+ T cell infiltration, elevates Granzyme B, lowers circulating MDSCs, and extends survival only in immune‐competent mice, but not in immune‐deficient mice.
Tzu‐Chieh Sun, Ching‐Fang Yu, Sheng‐Yan Wu, Wei‐Chung Cheng, Chi‐Shiun Chiang, Fang‐Hsin Chen   +5 more
wiley   +1 more source

InterPAD is a database of drug-drug interaction between phytochemicals and anticancer drugs. [PDF]

Sci Rep
Zhang A, Sun X, Wu Q, Jiang H, Xu L, Gao Q, Yang Z, Zhu S, Sui X.   +8 more
europepmc   +1 more source

The Possibility of Increasing Milk and Butterfat Production by the Administration of Drugs. II

, 1921
Andrew C. McCandlish, T. M. Olson
openalex   +1 more source

A single gene mutation predicts response to immune checkpoint blockade in ovarian clear cell carcinoma

Molecular Oncology, EarlyView.
Loss‐of‐function mutations in the scaffold subunit of protein phosphatase 2A (PP2A), PPP2R1A, sensitize ovarian clear cell carcinoma to immune checkpoint blockade (ICB) by enhancing the interferon gamma response and promoting antitumor immune cell infiltration.
Matheus Henrique Dias, René Bernards
wiley   +1 more source