Results 31 to 40 of about 3,598,260 (304)

Improvement of macrolactins production by the genetic adaptation of Bacillus siamensis A72 to saline stress via adaptive laboratory evolution

Microbial Cell Factories, 2022
Background Macrolactins, a type of macrolide antibiotic, are toxic to the producer strains. As such, its level is usually maintained below the lethal concentration during the fermentation process.
Yuman Gan, Meng Bai, Xiao Lin, Kai Liu, Bingyao Huang, Xiaodong Jiang, Yonghong Liu, Chenghai Gao   +7 more
doaj   +1 more source

The Integrated Model of Quality Management System of Laboratory Studies of Medicines (Review)

Разработка и регистрация лекарственных средств, 2021
Introduction. The publication is devoted to the role of laboratory research in ensuring the quality of domestic medicines and is a review and analysis of regulatory documents and current publications on this topic.Text.
A. I. Selezneva, V. A. Smirnov, V. V. Goryachkin, N. N. Chadova, S. V. Polyakov, V. N. Shestakov, R. A. Abramovich   +6 more
doaj   +1 more source

Drug–Drug Noninteractions

Cardiovascular Therapeutics, 2009
Understanding and documentation of drug–drug interactions (DDIs) are an important component of drug development, and of clinical therapeutics. Because clinical DDI studies are costly, time‐consuming, and involve some risk, not all clinical DDI questions can be realistically addressed through human DDI trials.In vitromodels have been used to identify ...
openaire   +2 more sources

Assessing suicidal risk with antiepileptic drugs [PDF]

, 2010
Marco Mula2, Gail S Bell1, Josemir W Sander1,31Department of Clinical and Experimental Epilepsy, UCL Institute of Neurology, and National Hospital for Neurology and Neurosurgery, UCL Hospitals NHS Foundation Trust, London, United Kingdom; 2Department of ...
Sander, JW, Marco Mula, Josemir W Sander, Bell, GS, Mula, M, Gail S Bell, Josemir Sander   +6 more
core   +1 more source

Drug-drug interaction

Jornal Brasileiro de Nefrologia, 2014
A doenca renal cronica (DRC), considerada a grande epidemia deste milenio, tem prevalencia media de 11% nos paises desenvolvidos. Infelizmente, no Brasil ainda nao dispomos de dados definitivos sobre a prevalencia da DRC, contudo, estudo realizado em amostra de 24.248 individuos adultos, utilizando o criterio de DRC baseado em duas determinacoes da ...
openaire   +2 more sources

European Standard Clinical Practice Guideline and EXPeRT Recommendations for the Diagnosis and Management of Gastroenteropancreatic Neuroendocrine Neoplasms in Children and Adolescents

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Pediatric gastroenteropancreatic neuroendocrine neoplasms (GEP‐NENs) are extremely rare and clinically heterogeneous. Management has largely been extrapolated from adult practice. This European Standard Clinical Practice Guideline (ESCP), developed by the EXPeRT network in collaboration with adult NEN experts, provides (adult) evidence ...
Michaela Kuhlen, Calogero Virgone, Antje Redlich, Michael Abele, Ricardo Lopez‐Almaraz, Tal Ben‐Ami, Ewa Bien, Gianni Bisogno, Maja Mazic Cesen, Andrea Ferrari, Malgorzata A. Krawczyk, Yves Reguerre, Dominik T. Schneider, Ines B. Brecht, Charlotte Rigaud, Bilgehan Yalcin, Rainer Claus, Christian Vokuhl, Constantin Lapa, Jörg Fuchs, Segolene Hescot, Thomas Walter, Julien Hadoux, Daniel Orbach   +23 more
wiley   +1 more source

Suicidal behavior and antiepileptic drugs in epilepsy: analysis of the emerging evidence [PDF]

, 2011
Marco Mula1, Dale C Hesdorffer21Department of Clinical and Experimental Medicine, Amedeo Avogadro University and Division of Neurology, University Hospital Maggiore della Carità, Novara, Italy; 2Gertrude H Sergievsky Center and Department of ...
Mula M, Mula, M, Hesdorffer DC, Hesdorffer, DC   +3 more
core   +1 more source

Interprofessional Approach to Increase Billable Care-Events in a Rural Community

INNOVATIONS in Pharmacy, 2017
Objectives: The study was designed to build a financially stable, replicable, and interprofessional program around a Center of Excellence (COE) model exclusively in a community pharmacy setting.
Geoffrey A Twigg, John Motsko, Jeff Sherr, Sara El-Baff   +3 more
doaj   +1 more source

Solid Pseudopapillary Neoplasm of the Pancreas in Children and Adolescents: Expert Recommendations

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Solid pseudopapillary neoplasm of the pancreas (SPN) is a rare low‐grade malignant exocrine pancreatic tumor, mostly discovered during the second decade of life in females, with a very good prognosis, provided microscopically complete surgical excision is achieved.
Sabine Irtan, Michael Abele, Calogero Virgone, Michaela Kuhlen, Ricardo Lopez‐Almarez, Tal Ben‐Ami, Ewa Bien, Maja Cesen, Malgorzata A. Krawczyk, Andrea Ferrari, Gianni Bisogno, Yves Reguerre, Dominik T. Schneider, Louise Galmiche, Jorg Fuchs, Sarah Braungart, Bilgehan Yalcin, Ines B. Brecht, Daniel Orbach   +18 more
wiley   +1 more source

The Ethics of “Smart Drugs”: Moral Judgments About Healthy People's Use of Cognitive-Enhancing Drugs [PDF]

, 2012
What moral concerns are relevant when judging the use of cognitive-enhancing (CE) drugs by healthy people? University students evaluated competitive fairness, distributive fairness, peer pressure, naturalness, and dosage form.

core   +3 more sources