Results 31 to 40 of about 8,070,517 (356)
Extensive impact of non-antibiotic drugs on human gut bacteria
Nature, 2018 A few commonly used non-antibiotic drugs have recently been associated with changes in gut microbiome composition, but the extent of this phenomenon is unknown.
Lisa Maier +12 more
semanticscholar +1 more source
Discovering the anti-cancer potential of non-oncology drugs by systematic viability profiling
Nature Cancer, 2020 Anticancer uses of non-oncology drugs have occasionally been found, but such discoveries have been serendipitous. We sought to create a public resource containing the growth-inhibitory activity of 4,518 drugs tested across 578 human cancer cell lines. We
Steven M. Corsello +37 more
semanticscholar +1 more source
The Ethics of “Smart Drugs”: Moral Judgments About Healthy People's Use of Cognitive-Enhancing Drugs [PDF]
, 2012 What moral concerns are relevant when judging the use of cognitive-enhancing (CE) drugs by healthy people? University students evaluated competitive fairness, distributive fairness, peer pressure, naturalness, and dosage form.
core +3 more sources
DrugBank: a knowledgebase for drugs, drug actions and drug targets
Nucleic Acids Res., 2007 DrugBank is a richly annotated resource that combines detailed drug data with comprehensive drug target and drug action information. Since its first release in 2006, DrugBank has been widely used to facilitate in silico drug target discovery, drug design,
D. Wishart +7 more
semanticscholar +1 more source
Cardiovascular Therapeutics, 2009 Understanding and documentation of drug–drug interactions (DDIs) are an important component of drug development, and of clinical therapeutics. Because clinical DDI studies are costly, time‐consuming, and involve some risk, not all clinical DDI questions can be realistically addressed through human DDI trials.In vitromodels have been used to identify ...
openaire +2 more sources
JAMA Network Open, 2019 Key Points Question What is the estimated percentage of US patients with cancer who are eligible for and respond to checkpoint inhibitor drugs approved for oncology indications by the US Food and Drug Administration?
A. Haslam, V. Prasad
semanticscholar +1 more source
Jornal Brasileiro de Nefrologia, 2014 A doenca renal cronica (DRC), considerada a grande epidemia deste milenio, tem prevalencia media de 11% nos paises desenvolvidos. Infelizmente, no Brasil ainda nao dispomos de dados definitivos sobre a prevalencia da DRC, contudo, estudo realizado em amostra de 24.248 individuos adultos, utilizando o criterio de DRC baseado em duas determinacoes da ...
openaire +2 more sources
Pediatric Blood &Cancer, EarlyView.ABSTRACT Pediatric gastroenteropancreatic neuroendocrine neoplasms (GEP‐NENs) are extremely rare and clinically heterogeneous. Management has largely been extrapolated from adult practice. This European Standard Clinical Practice Guideline (ESCP), developed by the EXPeRT network in collaboration with adult NEN experts, provides (adult) evidence ...
Michaela Kuhlen +23 more
wiley +1 more source
Interprofessional Approach to Increase Billable Care-Events in a Rural Community
INNOVATIONS in Pharmacy, 2017 Objectives: The study was designed to build a financially stable, replicable, and interprofessional program around a Center of Excellence (COE) model exclusively in a community pharmacy setting.
Geoffrey A Twigg +3 more
doaj +1 more source
Suicidal behavior and antiepileptic drugs in epilepsy: analysis of the emerging evidence [PDF]
, 2011 Marco Mula1, Dale C Hesdorffer21Department of Clinical and Experimental Medicine, Amedeo Avogadro University and Division of Neurology, University Hospital Maggiore della Carità, Novara, Italy; 2Gertrude H Sergievsky Center and Department of ...
Mula M +3 more
core +1 more source