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Genetic Distinctions Between Reticular Pseudodrusen and Drusen: Insights from a Genome-Wide Association Study

Schwartz R, Warwick AN, Khawaja AP, Luben R, Khalid H, Phatak S, Jhingan M, de Vente C, Valmaggia P, Liakopoulos S, Olvera-Barrios A, Sánchez CI, Egan C, Bonelli R, Tufail A.   +14 more
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SUBRETINAL DRUSENOID DEPOSITS AND SOFT DRUSEN

Retina, 2022
The two major phenotypes of intermediate age-related macular degeneration, soft drusen and subretinal drusenoid deposits, are shown here to have many distinguishing characteristics and few in common.
R. J. Thomson, J. Chazaro, O. Otero-Marquez, G. Ledesma-Gil, Yuehong Tong, A. C. Coughlin, Z. R. Teibel, S. Alauddin, K. Tai, Harriet Lloyd, M. Scolaro, A. Govindaiah, A. Bhuiyan, M. Dhamoon, A. Deobhakta, J. Narula, R. Rosen, L. Yannuzzi, K. Freund, R. T. Smith   +19 more
semanticscholar   +1 more source

MsTGANet: Automatic Drusen Segmentation From Retinal OCT Images

IEEE Transactions on Medical Imaging, 2021
Drusen is considered as the landmark for diagnosis of AMD and important risk factor for the development of AMD. Therefore, accurate segmentation of drusen in retinal OCT images is crucial for early diagnosis of AMD.
Meng Wang, Weifang Zhu, Fei Shi, Jinzhu Su, Haoyu Chen, Kai Yu, Yi Zhou, Yuanyuan Peng, Zhongyue Chen, Xinjian Chen   +9 more
semanticscholar   +1 more source

Case of the disappearing drusen

Canadian Journal of Ophthalmology, 2023
A 66-year-old man with age-related macular degeneration was admitted for new left cerebellar and right parietal hemorrhagic tumours. Excisional biopsy of the left cerebellar lesion demonstrated primary CNS lymphoma (PCNSL) of diffuse large B-cell morphology. No intraocular inflammation was present.
Haider, Ali S., Wight, Joel, Reddie, Ian C.   +2 more
openaire   +3 more sources

Glycoproteins of drusen and drusen-like lesions

Journal of Molecular Histology, 2007
Abstract Purpose: Drusen are a marker of age‐related macular degeneration. Lesions similar to drusen, both in histology and their clinical appearance are also seen in choroidal tumours, chronic inflammatory and degenerative conditions of the eye, and in mesangiocapillary glomerulonephritis type II (MCGN‐II).
D'Souza, Yvonne, Jones, C. J P, Bonshek, Richard   +2 more
openaire   +4 more sources

Optic disc drusen

The Lancet, 2003
85 Parle JV, Maisonneuve P, Sheppard MC, Boyle P, Franklyn JA. Prediction of all-cause and cardiovascular mortality in elderly people from one low serum thyrotropin result: a 10-year cohort study. Lancet 2001; 358: 861–65. 86 Mitsiades N, Poulaki V, Mitsiades CS, Koutras DA, Chrousos GP.
David Trew, Sobha Sivaprasad, Poorna Abeysiri   +2 more
openaire   +3 more sources

DRUSEN SUBTYPES AND CHOROIDAL CHARACTERISTICS IN ASIAN EYES WITH TYPICAL NEOVASCULAR AGE-RELATED MACULAR DEGENERATION.

Retina, 2020
PURPOSE To investigate the prevalence of pachydrusen, soft drusen, and subretinal drusenoid deposits in eyes with different neovascular age-related macular degeneration (nAMD) subtypes, determine the relationship between each drusen type and the ...
Junwon Lee, Min Kim, C. Lee, S. S. Kim, H. Koh, S. C. Lee, S. Byeon   +6 more
semanticscholar   +1 more source

Optic Nerve Drusen

Archives of Ophthalmology, 1973
Two case reports, one clinical and the other pathologic, illustrate important features of optic nerve drusen. A clinical subject demonstrates that optic nerve drusen cause visual field defects and central visual loss in childhood. Another case, studied postmortem, illustrates optic atrophy caused by drusen.
Robert S. Hepler, David F. Kamin, Robert Y. Foos   +2 more
openaire   +3 more sources

Optic Disk Drusen

Survey of Ophthalmology, 2002
Optic disk drusen occur in 3.4 to 24 per 1,000 population and are bilateral in approximately 75%. Disturbance in the axonal metabolism in the presence of a small scleral canal--regardless of eyelength--is considered responsible for the development. The drusen increase in size, becoming more visible with age due to continuing calcium apposition, and ...
Auw-Hädrich, Claudia, Staubach, Flemming, Witschel, Heinrich   +2 more
openaire   +4 more sources