Results 41 to 50 of about 5,455,798 (298)

Ironic Medications: A Narrative‐Based Psycho‐Educational Intervention to Explore Patient–Provider Communication in Adolescents With Haematological Cancer

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Adolescents with haematological malignancies face significant emotional and relational challenges, often accompanied by difficulties in communicating their needs within the healthcare context. To address these issues, a narrative‐based psycho‐educational intervention based on the creation and prescription of Ironic Medications was ...
Marta Stoppa, Elena Pagani Bagliacca, Selena Russo, Giulia Rampoldi, Maria Grazia Strepparava, Adriana Cristina Balduzzi, Andrea Biondi, Marco Spinelli   +7 more
wiley   +1 more source

Application of the Biorefinery Concept in the Processing of Crambe (Crambe abyssinica Hochst) Seed Defatted Meal in a Pressurized Medium

Plants
The valorization of byproducts such as defatted meal (DM) is essential for the implementation of a biorefinery structure and can be achieved through the application of emerging technologies, such as pressurized liquid extraction. This work aimed to apply
Camila da Silva, Jefferson Alessandro Schmitz, Djéssica Tatiane Raspe, Natália Stevanato, Jaqueline Hoscheid, Marcelino Luiz Gimenes, Beatriz Cervejeira Bolanho Barros, Lúcio Cardozo-Filho   +7 more
doaj   +1 more source

Populus tremula L. as a perspective source of preparations antiulcerous and anti-inflammatory activity

Бюллетень сибирской медицины, 2011
The results of these researches indicate the possibility of complex use of different parts of the aspen ordinary (Populus tremula L.), which are waste of wood processing industry and forestry engineering activities, and of the development of medical ...
V. F. Turetskova, I. Yu. Lobanova, S. S. Rassypnova, N. M. Talykova   +3 more
doaj   +1 more source

Development of the Composition and Technology of Capsules Containing Peony Evadiant Rhizomes and Roots Dry extract and Glycine

Разработка и регистрация лекарственных средств, 2023
Introduction. The development of dosage forms of sedative action is an urgent task of pharmaceutical technology in view of the prevalence of diseases of the nervous system.
E. A. Zamakhaeva, M. M. Smirnova, O. A. Oleshko, M. V. Chirkova   +3 more
doaj   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Technology of dry extract from the Filipendula ulmaria (L.) Maxim. and preliminary assessment of its safety profile

Разработка и регистрация лекарственных средств
Introduction. Medicines of natural origin have advantages over synthetic drugs and occupy a significant share in the assortment of pharmacies. Filipendula ulmaria (L.) Maxim., characterized by a chemical composition rich in phenolic compounds and various
E. Yu. Avdeeva, M. G. Skorokhodova, V. V. Sheikin, T. V. Kadyrova, M. V. Belousov   +4 more
doaj   +1 more source

Determination of Mercury Impurities in Protamine Sulfate Medicament by Stripping Voltammetry

Разработка и регистрация лекарственных средств, 2019
Introduction. The article presents data of the quantitative mercury determination in an aqueous solution of the pharmaceutical substance protamine sulfate by stripping voltammetry on graphite electrodes modified with a gold-polymer composition.
N. O. Kim, E. A. Ivanovskaja
doaj   +1 more source

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

FEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens, Brendan W. Chandler, Anna M. Schmoker, Jaye L. Weinert, Charlotte A. Kearns, Warren T. Yacawych, Amila Šemić, Alicia M. Ebert, Bryan A. Ballif   +8 more
wiley   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

FEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg, Martine Hjeltnes, Josephine Krieger, Joshua E. Elias, Maria Stensland, Kristian Holm, Xiaojun Jiang, Chuki Khangsar, Tuula A. Nyman, Arthur Kaser, Johannes R. Hov, Tom H. Karlsen, Nicole C. Kaneider, Frode L. Jahnsen, Georg Schneditz   +14 more
wiley   +1 more source

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

FEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas, Shahoon Khan, Abhishek Sharma, Byoungchun Lee, Savraj S. Grewal   +4 more
wiley   +1 more source