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Pharmacotherapy of dry eye

Expert Opinion on Pharmacotherapy, 2011
based on data from the largest studies of dry eye to date - the Women's Health Study (WHS) and the Physicians' Health Study (PHS) - and other studies, it has been estimated that about 3.23 million women and 1.68 million men, for a total of 4.91 million Americans aged ≥ 50 years, have dry eye. Tens of millions more have less severe symptoms and probably
Murat Dogru, Kazuo Tsubota
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Evaluation of Dry Eye

Survey of Ophthalmology, 2012
Dry eye is a common yet complex condition. Intrinsic and extrinsic factors can cause dysfunction of the lids, lacrimal glands, meibomian glands, ocular surface cells, or neural network. These problems would ultimately be expressed at the tear film-ocular surface interface.
Samantha McGinnigle   +2 more
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LASIK and dry eye

Ophthalmology, 2002
Abstract The following two letters address an article that appeared in the July 2001 issue of the Journal. Battat L, Macri A, Dursun D, Pflugfelder S. Effects of laser in situ keratomileusis on tear production, clearance, and the ocular surface (Ophthalmology 2001;108: 1230–5) .
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Diagnosis of Dry Eye

Survey of Ophthalmology, 2001
Dry eve disease is characterized by symptoms, ocular surface damage, reduced tear film stability, and tear hyperosmolarity. There are also inflammatory components. These features can be identified by various kinds of diagnostic tests (symptom questionnaires, ocular surface staining, tear break-up time, and osmometry), although there may not be a direct
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Clinical Trials in Dry Eye in Surgery for Dry Eye?

2008
To provide an overview of considerations in the design and performance of prospective clinical trials in the evaluation of new pharmaceutical and surgical treatments in dry eye disease (DED).A compilation and interpretation of experiences in the challenges and pitfalls of clinical trial design based on experiences documented in the peerreviewed ...
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Ptyerygium and Dry Eye

Ophthalmologica, 2001
<i>Purpose:</i> To assess the correlation between dry eye and pterygium. <i>Methods:</i> Tear breakup time (BUT), Schirmer test with/without anesthesia and tear function index were evaluated in both eyes of patients with unilateral pterygium.
Shigeto Shimmura   +3 more
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Dry eye syndrome

Drugs of Today, 1998
The present review is of dry eye syndrome, an entity caused by various conditions that lead to tear film abnormalities. The tear film consists of aqueous, mucin, proteins and lipids. Dry eye syndrome may be caused by local ocular disorders or systemic diseases.
Khalid F. Tabbara, Nariman A. Sharara
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Dry Eye and Closed Eye Tears

Cornea, 2000
To establish accurate measurement of tear production in the diagnosis and monitoring of dry eye.Reexamination of the Schirmer test indicated that the rate of tear secretion decreases with advancing age. We measured the noninvasive tear film break-up time (NIBUT) in normal and dry eye patients with our original apparatus.
Hsiao-Fu Wang, Masahiko Fukuda
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Dry eye disease, dry eye symptoms and depression: the Beijing Eye Study

British Journal of Ophthalmology, 2013
To investigate the association between dry eye symptoms and depression in an adult population.In this population-based cross-sectional study, a random sample of 1957 subjects from the Beijing Eye Study was examined for dry eye disease (DED) in 2006.
Jost B. Jonas   +6 more
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The Treatment of Dry Eye

Survey of Ophthalmology, 2001
The most widely used therapy for dry eye disease is tear replacement by topical artificial tears. Punctal occlusion to prevent the drainage of natural or artificial tears is the most common non-pharmacological treatment. These and other traditional therapies for dry eye disease are only palliative, however, as they replace or conserve the tears without
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