Results 171 to 180 of about 44,198 (256)

Nanomedicines for Dry Eye Syndrome: Targeting Oxidative Stress with Modern Nanomaterial Strategies. [PDF]

Molecules
Krawczyk A, Stadler SM, Strzalka-Mrozik B.   +2 more
europepmc   +1 more source

Conjunctival Sac‐Derived Lactobacillus mucosae MM‐1 Metabolite Indole‐3‐Lactic Acid Attenuates Lens‐Induced Myopia in Mice via AHR Activation and TGF‐β/Smad Inhibition

Microbial Biotechnology, Volume 19, Issue 8, August 2026.
This study proposes a ‘conjunctival sac microecology‐metabolite‐scleral remodelling’ regulatory axis, highlighting the potential role of conjunctival sac microbiota in maintaining ocular surface health and regulating lens‐induced myopia in mice, providing an important theoretical foundation for the development of microbiome‐based interventions for ...
Yanqing Li, Qiuyu Wu, Xilong Zhang, Luchuan Liu, Leiping Ding, Jingjing Xu, Chiwen Cheng, Yangyang Peng, Kang Yu, Wen Yao, Yijie Pi, Jiale Li, Di Wu, Jing Wei, Yifeng Yu, Tingtao Chen   +15 more
wiley   +1 more source

Quality of Life and Symptomatology in Neuropathic Corneal Pain in Comparison With Dry Eye Syndrome. [PDF]

Cornea
Chin JY, Tong L, Liu C, Lee IXY, Wong JHF, Wong RKT, Mehta JS, Liu YC.   +7 more
europepmc   +1 more source

Randomized, single‐centre, double‐blinded repeated dose investigation of safety and tolerability of ocular administrations of a novel silica eye drop product in healthy volunteers

Acta Ophthalmologica, Volume 104, Issue 5, Page 572-579, August 2026.
Abstract Purpose Managing ocular diseases often requires frequent eye drop administration, which can challenge patient compliance. A long‐acting eye drop technology using an amorphous synthetic silica composite was developed to address this. Our study aimed to assess the safety and tolerability of the Silica Eye Drop platform in healthy volunteers over
Aleksandra Poluianova, Marceline N. Akieh‐Pirkanniemi, Arto Hartikainen, Hanna Arstila, Kai Kaarniranta, Lasse Leino   +5 more
wiley   +1 more source

Reducing ocular <i>Demodex</i> using petroleum jelly may alleviate dry eye syndrome, blepharitis, facial dermatoses, ocular and respiratory allergies, and decrease associated prescribing: a hypothesis. [PDF]

Front Allergy
Senior-Fletcher DE.
europepmc   +1 more source

Repeatability of keratometry depending on tear film osmolarity

Acta Ophthalmologica, Volume 104, Issue 5, Page e530-e537, August 2026.
Abstract Purpose To determine the repeatability of keratometry and astigmatism measurements of patients depending on the tear film osmolarity using three different devices. Methods In this study, 97 eyes of 97 patients with a mean age of 64.92 ± 12.07 years received three repeated measurements with the IOLMaster 700 (Carl Zeiss Meditec, Jena, Germany),
David Schneider, Klemens Paul Kaiser, Petra Davidova, Thomas Kohnen, Tyll Jandewerth   +4 more
wiley   +1 more source

Repurposing Alzheimer's disease medications-systemic cholinesterase inhibitors-for the treatment of dry eye syndrome, glaucoma, and age-related macular degeneration. [PDF]

Ther Adv Ophthalmol
Rajagopal S, Ahuja P, Quach V, Luong C, Raji MA.   +4 more
europepmc   +1 more source

Risk of Age‐Related Ocular Diseases in Non‐Diabetic Adults With Obesity Using Glucagon‐Like Peptide 1 Receptor Agonists

Diabetes, Obesity and Metabolism, Volume 28, Issue 8, Page 7580-7591, August 2026.
ABSTRACT Aims To assess whether glucagon‐like peptide‐1 receptor agonists (GLP‐1RAs) are associated with a lower incidence of age‐related ocular diseases in non‐diabetic older adults with overweight or obesity. Materials and Methods We conducted a retrospective, propensity score–matched cohort study using the TriNetX global research network.
Kuo‐En Chen, Po‐Chun Wang, Hui‐An Lin, Sheng‐Feng Lin   +3 more
wiley   +1 more source

Evaluation of dry eye syndrome in patients with obstructive sleep apnea syndrome based on serum hypoxia-inducible factor 1 alpha (HIF-1α), matrix metalloproteinase 2 (MMP-2), and desmosine levels. [PDF]

BMC Ophthalmol
Okutucu M, Sağır B, Şahin Ü, Arpa M, Yılmaz E, Uzun F, Fındık H, Kaim M, Halili E.   +8 more
europepmc   +1 more source

Single‐Cell RNA Sequencing Revealed the Role of Interferon‐Gamma Related Genes in Primary Sjögren's Syndrome

Journal of Cellular and Molecular Medicine, Volume 30, Issue 15, August 2026.
ABSTRACT Primary Sjögren's syndrome (pSS) is a chronic autoimmune disorder. Dysregulated interferon‐gamma (IFN‐γ) signalling is implicated in pSS pathogenesis, yet the underlying mechanisms remain elusive. This study aimed to identify key IFN‐γ‐associated diagnostic genes and delineate their roles in immune dysregulation using peripheral blood ...
Lei Shi, Tian‐chi Wei, Jing Zhang
wiley   +1 more source