This study presents a bioengineered assembloid (ASM) system combining glioblastoma (GBM) cells in oxidized alginate (OA) microgels with dorsal organoids (DOs). This model simulates brain tumor‐host interactions, revealing enhanced GBM invasion, altered gene expression, and aggressive infiltration patterns, demonstrating ASM as a valuable platform for ...
Chao Liang +17 more
wiley +1 more source
Nutritional Supply vs. Flavor Quality: Characterizing the Physicochemical Properties and Amino Acid Profiles of Tomatoes from Beijing and Shandong. [PDF]
Zhao Y +11 more
europepmc +1 more source
A long‐lived, five‐cell‐type human neurovascular (PENTA) model recreates vascular disorganization and incomplete repair after traumatic brain injury (TBI). By integrating endothelial, glial, neuronal, and immune components within a 3D scaffold, the platform enables time‐resolved analysis of neurovascular remodeling and provides a human‐relevant system ...
Daniel S. Hinrichsen +6 more
wiley +1 more source
The relationship of rice yield and quality with the utilization of temperature and light resources in regions at different altitudes. [PDF]
Li R +14 more
europepmc +1 more source
Multidimensional Cellular Micro‐Compartments to Model Invasive Lobular Carcinoma Dormancy
Invasive lobular carcinoma (ILC) is an understudied subtype of breast cancer that is susceptible to late recurrences. In this study, micro‐compartmentalization techniques spanning multiple dimensions, including 2D, pseudo‐3D, and 3D, are integrated to uncover the mechanisms underlying ILC dormancy, revealing the central role of p27Kip1.
Xilal Y. Rima +15 more
wiley +1 more source
Composted organic manures modulated soil-microbe interactions that enhanced the growth of tobacco by improving rhizospheric microbial structure and soil nutrients. [PDF]
Shi N +11 more
europepmc +1 more source
This study investigates the M13 bacteriophage as a biomimetic nanovector capable of crossing in vitro models of the blood–brain barrier. By exploiting peculiar transcellular pathways, M13 avoids lysosomal degradation and preserves its structural integrity and functionality.
Silvia Vercellino +12 more
wiley +1 more source
Use of Humic Acids, Zeolite and Bentonite to Mitigate Iron Toxicity and Improve Growth Parameters and Chemical Composition in Maize (<i>Zea mays</i> L.). [PDF]
Wyszkowski M, Kordala N.
europepmc +1 more source
This systematic review quantitatively compares conventional mechanical stimulation strategies in cartilage tissue engineering across 85 heterogeneous in vitro studies. Applying standardized effect measures, meta‐analysis reveals that combined compression and shear loading optimally promotes cartilage matrix development.
Jiaqi K. Shen +7 more
wiley +1 more source
Coordinated Application of Nitrogen and Sulfur Synergistically Enhances Grain Yield and Grain Protein Concentration of Rice by Regulating Plant Growth. [PDF]
Wang H +11 more
europepmc +1 more source

