Results 81 to 90 of about 8,921,832 (256)

Regulation of the lncRNA NEAT1 by p53‐ΔNp63 crosstalk modulates the DNA damage response and therapeutic efficacy in HNSCC

open access: yesMolecular Oncology, EarlyView.
In head and neck squamous cell carcinoma (HNSCC) p53 and p63 exert opposite roles on the transcription regulation of the lncRNA NEAT1. Under basal conditions, p53 levels are low and p63 represses NEAT1 expression. Upon genotoxic stress, p53 is rapidly induced, displacing p63 from the NEAT1 promoter leading to NEAT1 transcriptional activation and ...
Sara De Domenico   +5 more
wiley   +1 more source

The Relationship Between Dry Matter Accumulation and Grain Yield in Different Ecological Types of Winter Wheat

open access: yesShuitu baochi yanjiu, 1988
Six cultivars were chosen for the study on the relationship between dry matter production and grain yield in different ecological types of wh- eat(T.aestivum).CV.Fushe No.63 for winter type;Xiannong No.68-3 and Xian No.8 for semi-winter type;Zheng yin No.
Liang Yinli
doaj  

Extracellular matrix remodeling and immune reprogramming drive residual tumor progression of liver cancer after incomplete microwave ablation

open access: yesMolecular Oncology, EarlyView.
Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu   +9 more
wiley   +1 more source

Effects of Reduced Nitrogen Application on Dry Matter and Yield of Direct-Seeded Hybrid Rice in Low-Light Regions of Sichuan Province

open access: yesGuangdong nongye kexue
【Objective】To clarify the responses of dry matter and yield of hybrid rice in the hilly areas of northwestern Sichuan to the reduction of nitrogen fertilizer application.【Method】'Jinlongyou 589' and 'Shenyouyuehesimiao' were selected as the experimental ...
Ran WANG   +10 more
doaj   +1 more source

SPHINX31 acts as a SRPK1 inhibitor targeting the ATR/DNA‐PKcs/CHK1 replicative checkpoint to inhibit cell growth in non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim   +17 more
wiley   +1 more source

Remote sensing of total dry-matter accumulation in winter wheat [PDF]

open access: yes, 1980
The author has identified the following significant results. Red and photographic-infrared spectral data collected on 21 dates over the growing season with a hand-held radiometer was quantitatively correlated with total dry-matter accumulation in winter ...
Holben, B. N.   +3 more
core  

Dry matter and nutrient accumulation in corn hybrids from the 1960's to 2000's [PDF]

open access: yes, 2015
How a Corn Plant Develops (Ritchie et al., 1986) was a popular reference for dry matter and nutrient accumulation; however, the data it contained was done in the late 1950's and was out of date.
Boyer, Matt
core   +1 more source

Targeting the EpCAM‐AXL axis to overcome drug resistance in lung cancer

open access: yesMolecular Oncology, EarlyView.
Lung cancer cells often evade therapy by hijacking signaling pathways. We reveal that cleaved EpCAM (sEpCAM) stabilizes the oncogenic protein AXL, driving NF‐κB and STAT3‐mediated chemoresistance. This EpCAM‐AXL axis identifies a high‐risk patient subset with poor prognosis.
Alexa Guerrero‐Alba   +5 more
wiley   +1 more source

Reprogramming tumor cells with LCOR mRNA nanotherapy to enhance immunotherapy

open access: yesMolecular Oncology, EarlyView.
LCOR (Ligand‐dependent corepressor) mRNA encapsulated in polymeric nanoparticles restores LCOR activity in tumor cells, constraining aggressive tumor cell states and increasing tumor immunogenicity. This reprogramming makes tumor cells more vulnerable to T‐cell attack and enhances their response to immune‐checkpoint immunotherapy.
Gabriel Serra‐Mir   +9 more
wiley   +1 more source

Dry matter and nutrients accumulation in mombasa guineagrass in function of nitrogen fertilization management

open access: yes, 2018
The nitrogen is an element extremely important in forage, being the nutrient more influence on productivity and quality of pasture. The objective was to study a pasture with high yield potential using sources and rates of nitrogen.
Buzetti, Salatier   +4 more
core   +1 more source

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