Results 121 to 130 of about 10,916 (286)

A 3D Bioprinted Spheroid‐Laden dECM‐Enriched Osteosarcoma Model for Enhanced Drug Testing and Therapeutic Discovery

Advanced Healthcare Materials, EarlyView.
A 3D biomimetic OS model was developed by bioprinting an OS‐cell‐derived dECM‐enriched bioink with OS spheroids incorporated. The model showed upregulation of known OS prognostic markers and increased resistance to doxorubicin, compared to 2D cultures and scaffold‐free spheroids, making this a more clinically relevant platform for drug discovery ...
Margarida F. Domingues, Maria Catarina Carreira, Mafalda S. Santos, Daniela Pacheco, Frederico Castelo Ferreira, Paola Sanjuan‐Alberte, João Carlos Silva   +6 more
wiley   +1 more source

Investigation of low-cost fabrication of ablative heat shields [PDF]

The fabrication, testing, and evaluation of materials and techniques employed in the fabrication of ablative heat shield panels are described. Results of this effort show projected reductions in labor man-hours for dielectric curing of panels when ...
Mach, R. W., Massions, V. P.
core   +1 more source

The Impact of Quadratus Plantae Muscle Dry Needling on Pain and Thickness of the Plantar Fascia in Individuals With Plantar Fasciitis [PDF]

Physical Treatments
Purpose: Plantar fasciitis (PF) is a leading cause of foot discomfort and significantly impacts the overall quality of life. Trigger points dry needling is an alternative treatment for heel pain.
Zeinab Mahmoudi, Roghayeh Mohammadi, Fatemeh Paknazar   +2 more
doaj  

Spatial Patterning of Modular Gelatin‐Peroxide Microspheres in Melt‐Electrowritten Scaffolds Provides Controlled Oxygen Generation and Mitigates Hypoxia and Cytotoxicity

Advanced Healthcare Materials, EarlyView.
A bioassembly approach is described using photo‐crosslinked gelatin‐based microgels containing calcium peroxide (CaO2) to generate oxygen (O2) and enhance cell survival in hypoxic conditions (1% O2). Bioassembly enables spatial patterning of individual CaO2‐laden and mesenchymal stem cell (MSC)‐laden microgels and allows for decoupling and mitigating ...
Axel E. Norberg, F. Max Yavitt, Ezgi Bakirci, Khoon Lim, Tim B. F. Woodfield, Gabriella C. J. Lindberg   +5 more
wiley   +1 more source

Physiotherapy with and without Superficial Dry Needling Affects Pain and Muscle Strength in Patients with Patellofemoral Pain Syndrome

Iranian Rehabilitation Journal, 2016
Objectives: To investigate the clinical efficacy of physiotherapy with and without superficial dry needling on patients with knee pain; patellofemoral pain syndrome. Methods: A randomized clinical trial conducted in 2015, Tehran, Iran.
Hamideh Miri Abyaneh, Zahra Mosallanezhad, Hooman Mohammadalizade, Enayatollah Bakhshi, Ghazaleh Vahedi, Mohammad Reza Nourbakhsh   +5 more
doaj  

Patient‐Derived 3D Bioprinted Cardiac Organoid Constructs Reveal Key Pathological Features of Duchenne Muscular Dystrophy

Advanced Healthcare Materials, EarlyView.
Patient‐derived cardiac organoids reveal key features of Duchenne muscular dystrophy cardiomyopathy, including apoptosis, oxidative stress, calcium handling defects, and mechanical remodeling. By integrating organoids into alginate–gelatin bioprinted constructs, disease phenotypes are organized into scalable 3D cardiac tissues displaying extracellular ...
Vittoria Marini, Margalida Campaner Socias, Andreas Dimopoulos, Lorenza Rinvenuto, Enrico Pozzo, Diana Stalkopf, Angelo Serafini, Sara Morri, Ashley Wang, Rita La Rovere, Yoke Chin Chai, Sveva Bollini, Geert Bultynck, H. Llewelyn Roderick, Ioannis Papantoniou, Maurilio Sampaolesi   +15 more
wiley   +1 more source

Effects of dry needling on spasticity, cortical excitability, and range of motion in a patient with multiple sclerosis: a case report

Journal of Medical Case Reports
Background Dry needling is an intervention used by physiotherapists to manage muscle spasticity. We report the effects of three sessions of dry needling on ankle plantar flexor muscle spasticity and cortical excitability in a patient with multiple ...
Haniyeh Choobsaz, Nastaran Ghotbi, Noureddin Nakhostin Ansari   +2 more
doaj   +1 more source

Morphological Alterations in Needle Tip following Trigger Point Dry Needling

Indian Journal of Pain, 2023
Manoj Kumar Sharma, Hardika Sood
openaire   +2 more sources

A 3D Astrocyte Microenvironment Model Enables Rapid Ca2+‐Resolved Analysis and Therapeutic Modulation of Oxidative Neuroinflammation

Advanced Healthcare Materials, EarlyView.
This work presents ARC‐3D, a soft 3D model that recreates how brain support cells, called astrocytes, react to oxidative stress. The system visualizes rapid calcium changes and inflammatory signals, and shows how the drug KDS12025 can protect cells from damage. ARC‐3D offers a simple, reliable way to study early drivers of brain inflammation.
Ju‐Kang Kim, Ye‐Ji Kim, Seyoung Ryu, Daeui Park, Kyoung‐Sik Moon, Yu Bin Lee, Dong Ho Woo   +6 more
wiley   +1 more source

Trigger point dry needling for the treatment of myofascial pain syndrome: current perspectives within a pain neuroscience paradigm

Journal of Pain Research, 2019
César Fernández-de-Las-Peñas,1,2 Jo Nijs3,41Department of Physical Therapy, Occupational Therapy, Rehabilitation and Physical Medicine, Universidad Rey Juan Carlos, Alcorcón, Madrid, Spain; 2Cátedra de Investigaci ...
Fernández-de-Las-Peñas C, Nijs J
doaj