Results 121 to 130 of about 4,305 (256)

ANKS1B in the Nucleus Accumbens Controls Escalated Cocaine Self‐Administration via Regulating CBP‐FoxO3 Complex

Advanced Science, EarlyView.
ANKS1B in the nucleus accumbens plays a critical role in the transition from controlled to escalated cocaine intake. Mechanistically, ANKS1B interacts with CBP to epigenetically suppress FoxO3 through H3K27 acetylation. The ANKS1B‐CBP‐FoxO3 signaling cascade presents a novel theraputic target for the treatment of cocaine addiction.
Liping Yang, Xiaoxuan Wu, Xuan Chen, Chao Peng, Zihang Li, Shumin Gao, Shiqiu Meng, Jing Dong, Dong Wu, Liying Lv, Ying Han, Yanxue Xue, Lin Lu, Jie Shi, Jianfeng Liu, Yan Sun   +15 more
wiley   +1 more source

CARE-DN: An Extension of the CARE Guidelines for Dry Needling Case Reports. [PDF]

Cureus
Tzigkounakis G, Simati K, Georgiadis K, Kostaridou V, Battersby P, Calvo S, Herrero P, Kuzdzal A, McEvoy J, Sánchez Milá Z, Velázquez Saornil J, Voight M, Wang T, Stefanakis M.   +13 more
europepmc   +1 more source

Integrative Multi‐Omics Analysis Reveals a Mitochondrial–Immune Axis Associated With Neoadjuvant Chemotherapy Response in High‐Grade Serous Ovarian Cancer

Advanced Science, EarlyView.
Integrative multi‐omics analysis delineates a mitochondrial–immune axis governing neoadjuvant chemotherapy response in high‐grade serous ovarian cancer. Immune‐active tumors exhibit enhanced B‐cell infiltration and favorable sensitivity, whereas metabolically rewired tumors display oxidative phosphorylation dependency and resistance.
Wei Jiang, Yi Wang, Xiaohang Lu, Qianlan Yao, Libing Xiang, Xu Cai, Xiaoyu Tu, Shaoxian Tang, Ying Xu, Yufan Cheng, Liming Shen, Huijuan Yang   +11 more
wiley   +1 more source

Effectiveness of Repetitive Peripheral Magnetic Stimulation (rPMS) in Relieving Post-Needling Soreness in Patient with Upper Trapezius Myofascial Pain Syndrome: A Double-Blind, Randomized Clinical Trial

Journal of Pain Research
Anja Vearasilp, Chomkajee Sukareechai Department of Rehabilitation Medicine, Panyananthaphikkhu Chonprathan Medical Center Srinakharinwirot University, Nonthaburi, ThailandCorrespondence: Chomkajee Sukareechai, Department of Rehabilitation Medicine ...
Vearasilp A, Sukareechai C
doaj  

Comparison of ultrasound-guided dry needling and platelet-rich plasma injection in the management of refractory lateral epicondyle tendinopathy. [PDF]

Clin Shoulder Elb
Terzi MM, Kıratlıoğlu Y, Bezirgan U, Armangil M.   +3 more
europepmc   +1 more source

Microglial Deubiquitinase OTUD7B Stabilizes STAT3 to Promote Neuroinflammation and Cognitive Decline in Alzheimer's Disease

Advanced Science, EarlyView.
. ABSTRACT Neuroinflammation driven by microglial activation is a defining feature of Alzheimer's disease (AD), yet the molecular mechanisms sustaining this proinflammatory state remain unclear. Here, we identify the deubiquitinase OTUD7B as a critical regulator of microglial activation and AD pathology.
Luyao Li, Hao Tang, Qin Yu, Yuyang Zhang, Binglu Shi, Ying Kong, Leiyu Xu, Jingjing Shao, Chenghong Hu, Lingyu She, Zhe Wang, Haiyi Chen, Aleksandr V. Samorodov, Gang Cao, Xia Zhao, Yi Wang   +15 more
wiley   +1 more source

Effectiveness of Dry Needling Versus Percutaneous Electrolysis in Achilles Tendinopathy: A Randomized Clinical Trial. [PDF]

Cureus
Delgado Álvarez S, Méndez Sánchez R, Polo Ferrero L, Rodríguez Fragua I, Loaiciga Espeleta C, González Raja R, Sánchez Milá Z, Velázquez Saornil J.   +7 more
europepmc   +1 more source

Astrocytic Phenotypic Switching in Posterior Piriform Cortex Orchestrates Bone Cancer Pain–Depression Comorbidity via Purinergic–Noradrenergic Signaling

Advanced Science, EarlyView.
Bone cancer pain and depression share a common origin: astrocytic A2‐to‐A1 transition in the posterior piriform cortex. This phenotypic shift disrupts the ATP–adenosine–A2AR–norepinephrine axis, simultaneously driving nociceptive and affective dysfunction.
Jiang‐Ping Liu, Jun‐Han Zhang, Zhi‐Xuan Tan, Wei‐Bing Yan, Ya‐Ru Yuan, Yao Liu, Bing‐Di Wei, Meng‐Qi Ding, Zhuo‐Min Fu, Ying Liu, An‐Qi Wang, Lin Ma, Yong‐Hong Li, Er‐Qing Chai, Chao‐Jun Wei   +14 more
wiley   +1 more source

Role of Dry Needling in Management of Cervicogenic Headache: A Systematic Review

Journal Riphah College of Rehabilitation Sciences
Background: Cervicogenic headache is one of the most common types of headache. It is caused due to musculoskeletal dysfunction in the cervical muscles. The underlying mechanisms involve myofascial trigger points.
Meerab Khurshid, Komal Amin, Sheeza Nadeem, Rabia Jawa   +3 more
doaj  

Collagen injections versus dry needling in the treatment of chronic supraspinatus tendinopathy: a randomized controlled trial. [PDF]

Front Surg
Chirico VA, Mazzuoccolo G, Saracco M, Tarantino D, Ruosi C, Corrado B.   +5 more
europepmc   +1 more source