Results 151 to 160 of about 908,468 (287)

Neurophysiological and Structural-Mechanical Changes Associated with Dry Needling in Post-Stroke Spasticity: A Systematic Review. [PDF]

J Clin Med
Eeckhaut B, Truijen S, Leroij C, Dévillé J, Jacobs L, Saeys W.   +5 more
europepmc   +1 more source

Innate Immunocompetent hiPSC‐Derived Neurospheroids Capture Early CNS Responses to rAAV

Advanced Science, EarlyView.
Knowledge of human CNS immune responses to AAV‐based gene therapies remains limited due to the lack of immune‐competent human models. Here, a hiPSC‐derived 3D neuroimmune platform integrating neurospheroids and microglia is established using stirred‐tank bioreactors.
Catarina M. Gomes, Gabriela Silva, Mafalda Aleixo, Marta Gomes, Daniel Simão, Stephan J. Holtkamp, Diana D. Lobo, Pradeep Harish, Rosalind Jenkins, Lekh N. Dahal, Rui J. Nobre, Luís de Pereira de Almeida, Mark Trautwein, Paula M. Alves, Catarina Brito   +14 more
wiley   +1 more source

Effects on deep dry needling of the TIBIALIS posterior muscle on plantar pressure distribution: A single-blinded randomized controlled baropodometric trial. [PDF]

PLoS One
Martínez-González MC, Del-Río-Medina S, Montero-Navarro S, Sánchez-Más J, Rocha-Ortiz MI, Molina-Payá FJ, Orts-Ruiz C, Salar-Andreu C, Calderón-Santos LE, Botella-Rico JM, Morera-Balaguer J.   +10 more
europepmc   +1 more source

GHRHR Deficiency Enhances Retinal Ganglion Cell Survival and Visual Functions in Experimental Glaucoma by Inhibiting Ferroptosis

Advanced Science, EarlyView.
Glaucoma, a major cause of blindness, involves retinal ganglion cell (RGC) degeneration. This study shows growth hormone‐releasing hormone receptor (GHRHR) deficiency preserves RGC survival and restores vision, unlike activation which only aids survival.
Yan Tong, Ming Ho Yam, Jiaxin Zhang, Lin Du, Linbin Zhou, Yolanda Wong Ying Yip, Bo Man Ho, Hemlata Bisnauthsing, Jiahui Li, Ivan Kong, Shushu Xu, Changzhen Fu, Karl K.H. So, Joaquim S.L. Vong, Ling‐Ping Cen, Ming‐Ming Yang, Khazeema Yousaf, Mai Har Sham, Sun On Chan, Poemen P. Chan, Chi Pui Pang, Clement C. Tham, Jing Na He, Jian Li, Wai Kit Chu   +24 more
wiley   +1 more source

Effectiveness of Repetitive Peripheral Magnetic Stimulation (rPMS) in Relieving Post-Needling Soreness in Patient with Upper Trapezius Myofascial Pain Syndrome: A Double-Blind, Randomized Clinical Trial

Journal of Pain Research
Anja Vearasilp, Chomkajee Sukareechai Department of Rehabilitation Medicine, Panyananthaphikkhu Chonprathan Medical Center Srinakharinwirot University, Nonthaburi, ThailandCorrespondence: Chomkajee Sukareechai, Department of Rehabilitation Medicine ...
Vearasilp A, Sukareechai C
doaj  

Treatment Guidelines and Decision Tree for Dry Needling Musculoskeletal Conditions: A Consensus Statement. [PDF]

Int J Sports Phys Ther
Waterway T, Beougher J, Butler R, Church K, Cook G, Falsone S, Hortz B, Opitz T, Plisky PJ, Zylstra E, Martin R.   +10 more
europepmc   +1 more source

Microglial Deubiquitinase OTUD7B Stabilizes STAT3 to Promote Neuroinflammation and Cognitive Decline in Alzheimer's Disease

Advanced Science, EarlyView.
. ABSTRACT Neuroinflammation driven by microglial activation is a defining feature of Alzheimer's disease (AD), yet the molecular mechanisms sustaining this proinflammatory state remain unclear. Here, we identify the deubiquitinase OTUD7B as a critical regulator of microglial activation and AD pathology.
Luyao Li, Hao Tang, Qin Yu, Yuyang Zhang, Binglu Shi, Ying Kong, Leiyu Xu, Jingjing Shao, Chenghong Hu, Lingyu She, Zhe Wang, Haiyi Chen, Aleksandr V. Samorodov, Gang Cao, Xia Zhao, Yi Wang   +15 more
wiley   +1 more source

Trigger Point Electrical Dry Needling with Different Waveforms for Knee Osteoarthritis: Mechanistic Insights and Methodological Considerations [Letter]. [PDF]

J Pain Res
Yu Y, Zhang H, Hu X, Liu Y, Zhang M, Zhang C, Wang L.   +6 more
europepmc   +1 more source

Ultrasound‐Responsive Piezoelectric Fibrous Membrane Promotes Neurological Recovery After TBI by Modulating Microglial Polarization via Restoring Mitochondrial Dynamic Homeostasis

Advanced Science, EarlyView.
We demonstrate a novel therapy for traumatic brain injury TBI using a LIPUS‐responsive Piezoelectric fibrous membrane. It targets microglial mitochondria via in situ electrical signals, restoring homeostasis and reducing oxidative stress to promote an anti‐inflammatory M2 phenotype.
Wei Li, Runzhe Huang, Qingyuan Wu, Pengbo Zhou, Dangli Ren, Jingjing Wang, Hanjie Niu, Zemeng Li, Hongtao Sun, Huiyu Liu   +9 more
wiley   +1 more source

Adjunctive dry needling reduces spasticity and improves functional outcomes in children with cerebral palsy: a single-blind randomized controlled trial. [PDF]

Front Pediatr
Alkhamees NH, Abdelraouf OR, Abdel Ghafar MA, Ibrahim ZM, Harraz EM, Seyam MK, Morsy WE, Ahmed MM.   +7 more
europepmc   +1 more source