Advanced Science, EarlyView.ABSTRACT Vascularization remains a major obstacle in tissue engineering. Here, we introduce a bioprinting strategy to generate centimeter‐scale, self‐organizing “mother vessel” constructs from iPSC‐derived hiMPCs. By optimizing bioink composition, printing was accomplished in a single‐step approach. Within one week, hiMPCs differentiated into both CD31+
Leyla E. Dogan +5 more
wiley +1 more source
Trigger Point Electrical Dry Needling with Different Waveforms Plus Intra-Articular Corticosteroid for Knee Osteoarthritis: A Prospective Randomized Controlled Trial. [PDF]
J Pain ResLin Y, Jia W, Liu C, Tang Y, Yuan Y.
europepmc +1 more source
Electrolyte Design for Simultaneous Interfacial Stabilization in Si||NCM811 Full Cells
Advanced Science, EarlyView.A dual‐additive electrolyte (DAEL) system was optimized to regulate interfacial reactions in both Si anode and the NCM811 cathode. DAEL suppresses gas evolution and degradation, enabling stable interphases. These synergistic effects enhance electrochemical stability and extend battery cycle life in high‐energy lithium‐ion cells.
Seo Yun Jang +6 more
wiley +1 more source
Ultrasound-guided percutaneous electrolysis versus dry needling in patients with chronic low back pain a double-blind randomized clinical trial. [PDF]
Sci RepSaavedra-Hernández M +5 more
europepmc +1 more source
A Ceramic Network for Hybrid Solid Electrolyte Lithium Metal Batteries
Advanced Science, EarlyView.An in‐plane aligned Ta‐LLZO ceramic network exhibits superior performance compared to conventional fillers, including single ceramic fibers and particles. The tortuosity within the polymeric phase of hybrid solid electrolytes is identified as a key parameter governing lithium‐ion transport pathways and dendrite suppression.
Luca Weckelmann +10 more
wiley +1 more source
A dual-database bibliometric analysis on dry needling for pain: Global trends and hotspots from web of science core collection and Scopus (2006-2025). [PDF]
Front NeurolLiao M, Cheng X, Liu F, Xiong X, Yu Y.
europepmc +1 more source
Mechanical Activation of Piezo1 Drives Osteoarthritis Through Kdm5c‐Mediated Epigenetic Silencing
Advanced Science, EarlyView.Excessive mechanical stress activates Piezo1, triggering Ca2+‐dependent cytoskeletal forces that deform the nucleus and reduce H3K4me3. Kdm5c demethylates H3K4me3 at Col2a1 and Runx3 promoters. Kdm5c knockout rescues degradation. Repurposed telmisartan directly inhibits Kdm5c, blocking this axis and showing disease‐modifying efficacy in mouse OA models
Tianyou Kan +13 more
wiley +1 more source
Dry needling versus platelet-rich plasma in myofascial pain: A randomized trial. [PDF]
BioinformationRani J +5 more
europepmc +1 more source
Study on the Reaction Mechanism of RuOx and Its Enhanced Hydrogen Evolution Reaction Activity
Advanced Science, EarlyView.In situ Raman spectroscopy and DFT calculations reveal that, prior to the onset of HER, the surface of RuOx undergoes reversible reduction and structural reconstruction. The resulting Ru(II)O/Ru(IV)O2 configuration is identified as the true catalytically active species.
Liquan Zhang +9 more
wiley +1 more source
Advanced Science, EarlyView.Cholesterol‐enriched plasma membranes in hepatocellular carcinoma impede drug penetration. Cholesterol (+)‐liposomes act as membrane‐specific detergents, extracting cholesterol and reducing barrier function without cytotoxicity. Following endocytosis, cholesterol transfers from endosomes to liposomes and is metabolized in the ER.
Chansik Kim +9 more
wiley +1 more source