BOULE is Essential for the Dynamic Disassembly of Heat Shock Granules in Male Germ Cells
BOULE orchestrates stress granule disassembly in germ cells via a two‐pronged mechanism: it promotes G3BP1 ubiquitination by upregulating TRIM27, generating a signal for VCP/FAF2 recruitment, and it maintains G3BP1 and FAF2 protein levels. BOULE deficiency disrupts disassembly complex formation, leading to impaired heat shock granule clearance ...
Xin Li +8 more
wiley +1 more source
Comparative effects of low-level laser acupuncture and dry needling on clinical and functional outcomes in patients with chronic cervical myofascial pain syndrome: a randomized controlled trial. [PDF]
Zaidi F +4 more
europepmc +1 more source
A biomimetic doppelgänger nanosystem neutralizes extracellular inflammatory cytokines and silences intracellular pyroptosis, reprogramming pathogenic macrophages to attenuate both joint and spine degeneration. ABSTRACT Osteoarthritis (OA) and intervertebral disc degeneration (IVDD) are debilitating musculoskeletal disorders driven by shared ...
Fudong Li +9 more
wiley +1 more source
Effects of dry needling on recovery, neuromuscular function, and injury outcomes in sports athletes: a systematic review targeting the neck and related regions. [PDF]
Olaniszyn G +4 more
europepmc +1 more source
In microglia, STAT3 upregulates TAB2, which promotes NF‐κB activation through its NZF domain‐mediated recognition of K63‐linked ubiquitin chains, leading to inflammatory cytokine release and subsequent neuronal injury. Lumacaftor suppresses TAB2 expression and directly binds the TAB2‐NZF domain to interrupt K63 ubiquitin recognition, thereby blocking ...
Yanhao Zhao +12 more
wiley +1 more source
Physiological correlates and predictors of vasovagal responses following dry needling in myofascial pain syndrome: a controlled observational study. [PDF]
Trybulski R +5 more
europepmc +1 more source
An ultrafast (2‐minute), gas‐free chemical pre‐sodiation strategy using Na‐benzophenone is developed to compensate for initial sodium loss in calcium vanadate (CaV8O20). Driven by the Ca2+ ‘spectator effect’, the framework enables highly reversible, quasi‐zero‐strain solid‐solution sodium storage, explicitly bypassing destructive conversion reactions ...
Neetu Bansal +7 more
wiley +1 more source
Trigger Point Electrical Dry Needling with Different Waveforms Plus Intra-Articular Corticosteroid for Knee Osteoarthritis: A Prospective Randomized Controlled Trial. [PDF]
Lin Y, Jia W, Liu C, Tang Y, Yuan Y.
europepmc +1 more source
An injectable gelatin‐based tannic acid–iron hydrogel with mild photothermal therapy could not only induce immunogenic cell death, but also elicit ferroptosis of both tumor cells and tumor‐associated macrophages, resulting in DC maturation, T‐cell infiltration and down‐regulation of ferroptosis‐sensitive M2‐type TAMs levels.
Yuan Zhu +10 more
wiley +1 more source
Ultrasound-guided percutaneous electrolysis versus dry needling in patients with chronic low back pain a double-blind randomized clinical trial. [PDF]
Saavedra-Hernández M +5 more
europepmc +1 more source

