Results 81 to 90 of about 363,214 (311)

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

Molecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller, Janina Müller, Efstathios‐Iason Vlachavas, Lukas Beumers, Lena Fleischhacker, Sara Burmester, Angelika Wörner, Sabine Karolus, Dominic Helm, Cindy Körner, Stefan Wiemann   +10 more
wiley   +1 more source

Correlation of physio-chemical characteristics in the seed coat and canning quality in different dark red kidney bean (Phaseolus vulgaris l.) cultivars [PDF]

, 2002
Plan BThe canned kidney bean (Phaseolus vulgaris L.) is one of the major consumption forms of this agricultural product. In the canning industry, seed coat splitting is considered one factor affecting the integrity of the appearance in the final product.
Wu, Xiaojun
core  

PROCESSING OF SPENT ZINC-MnO2 DRY CELLS IN VARIOUS ACIDIC MEDIA

Química Nova
This paper describes a route for recovering manganese and zinc from spent zinc-MnO2 dry cells via acid leaching. Sulfuric, hydrofluoric and formic acids were used as leachants.
Vinício Francisco Ibiapina, Ulysses dos Santos Florentino, Júlio Carlos Afonso, Valdir Gante, Cláudio Augusto Vianna, José Luiz Mantovano   +5 more
doaj   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

FEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point, Wafaa Achache, Janïs Laudouze, Eliana Sepulveda Ramos, Mickaël Maziero, Céline Crauste, Stéphane Canaan, Pierre Santucci   +7 more
wiley   +1 more source

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

FEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

FEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli, Mohammad Nour Alsamsam, Ugnė Bagdonaitė, Van Truc Vu, Chun‐Jen Huang, Polina Kuzhir, Mindaugas Zaremba, Aurimas Kopūstas, Marijonas Tutkus   +8 more
wiley   +1 more source

Progress and prospects in nanoscale dry processes: How can we control atomic layer reactions?

, 2017
In this review, we discuss the progress of emerging dry processes for nanoscale fabrication. Experts in the fields of plasma processing have contributed to addressing the increasingly challenging demands in achieving atomic-level control of material ...
Ishikawa, K., Lee, Hae June, W. M. M. Kessels, Kenji Ishikawa, Keizo Kinoshita, Kinoshita, Keizo, George, S.M., George, Steven M., Chang, J.P., Kinoshita, K., Lee, H.J., Steven M. George, Ishikawa, Kenji, Ichiki, T., Kazuhiro Karahashi, Hae June Lee, Ichiki, Takanori, Hwan Um, Jung, Karahashi, K., Jane P. Chang, Um, J.H., Stefan Tinck, Takanori Ichiki, Tinck, Stefan, Tinck, S., Jung Hwan Um, Karahashi, Kazuhiro, Chang, Jane P., Kessels, W.M.M.   +28 more
core   +1 more source

Effects of a straight oil on friction at the tool-workmaterial interface in machining [PDF]

, 2010
Authors would like to express their gratitude to the TOTAL Company for the furniture of the lubricant.The quantification of friction coefficient along the tool-workmaterial interface in machining remains an issue in tribology. This paper aims identifying
RECH, Joël, J. Rech, A. Mondelin, C. Claudin, G. Fromentin, FROMENTIN, Guillaume, MONDELIN, Alexandre, CLAUDIN, Christophe   +7 more
core   +1 more source

Image processing applied to tribological dry contact analysis

, 2022
International audienceThe prediction of dry friction requires a quantification of the rheology of the tribological interface (third body). Until now this rheology has been characterized qualitatively by a broad description of its morphology (from powdery
Bouchot, Alizée, Ferrieux, Amandine, Mollon, Guilhem, Descartes, Sylvie, Debayle, Johan   +4 more
core   +1 more source

Screening and epitope characterization of Nidogen‐2‐specific nanobodies

FEBS Open Bio, EarlyView.
Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen, Qianqian Cui, Zhongyun Lan, Yingjun Wang, Shuaiying Zhao, Wenxuan Feng, Yunfeng Liu, Qiting Huang, Dongna Zhang, Jianfeng Xu   +9 more
wiley   +1 more source