Results 131 to 140 of about 12,228 (202)

Effectiveness and experiences with differentiated service delivery of HIV care in Kisumu County, Kenya: A mixed methods study, 2014-2021.

PLOS Global Public Health
The adoption of the test and treat policy by the World Health Organization (WHO) in 2015 led to an unprecedented increase in the number of people living with HIV (PLHIV) enrolling into HIV treatment, thereby increasing the burden on HIV service delivery.
Francesca Odhiambo, Raphael Onyango Mando, Jayne Lewis-Kulzer, A Rain Mocello, Maurice Aluda, Edwin Mulwa, Appolonia Aoko, Paul Musingila, Elizabeth Bukusi, Craig R Cohen   +9 more
doaj   +1 more source

A Computational Framework for Myelin as a Regulator of Temporal Integration, Neuronal Excitability, and Synaptic Plasticity

Glia, Volume 74, Issue 12, December 2026.
Computational models illustrate how myelinating glia may shape the temporal integration of spikes upon a common postsynaptic target. Models show consequences for synaptic plasticity, neuronal excitability, and the fidelity of neural signals. ABSTRACT Myelin regulates neural signaling not only by enabling fast conduction but also by dynamically tuning ...
Daniel O'Sullivan, Aref Pariz, Daniel Trotter, Noor Z. Al Dahhan, Juliet K. Knowles, Paul W. Frankland, Donald Mabbott, Jérémie Lefebvre   +7 more
wiley   +1 more source

Expanded Phenotype Associated With an Intronic PPP1R12A Variant: A Case Report and Literature Review

American Journal of Medical Genetics Part A, Volume 200, Issue 11, Page 2519-2524, November 2026.
ABSTRACT Autosomal dominant PPP1R12A‐related genitourinary and/or brain malformation syndrome is a recently described multisystem disorder caused by loss‐of‐function variants in the protein phosphatase 1 regulatory subunit 12a (PPP1R12A) gene. To date, 22 affected individuals have been reported with variable brain malformations and genitourinary ...
Emily M. Bland, Amber Nakar Weinstein, Eric C. Kao, Xiaonan Zhao, Monika Weisz‐Hubshman   +4 more
wiley   +1 more source

Can Annotation‐Free Deep Learning Detect Periapical Bone Rarefactions on Panoramic Radiographs? A Paired Diagnostic Validation Study

International Journal of Imaging Systems and Technology, Volume 36, Issue 6, November 2026.
ABSTRACT This study aimed to compare an annotation‐free deep learning (DL) model with human evaluators for detecting periapical bone rarefactions (PBRs) on panoramic radiographs (PRs) and to assess the clinical acceptability of AI‐supported dental imaging.
José Evando da Silva‐Filho, Caio Marques Silva, Giovanna Tacchi, Igor Rodrigues‐Fontenele, Mateus Bôtto‐Marques, Sâmela Débora Mendes‐Dias, André Wescley Oliveira de Aguiar, Pedro Pedrosa Rebouças Filho, Paulo Leonardo Pontes Marques, Danielle Frota de Albuquerque, Eduardo Diogo Gurgel‐Filho   +10 more
wiley   +1 more source

Gender Dysphoria and Gender Change in Disorders of Sex Development/Intersex Conditions: Results From the dsd-LIFE Study

, 2018
International audienceBACKGROUND:Information on the psychosexual outcome of individuals with disorders of sex development (DSDs) and intersex conditions is of great importance for sex assignment at birth of newborns with DSD.AIM:To assess gender change ...
Kreukels, Baudewijntje, Köhler, Birgit, Peggy T. Cohen-Kettenis, Roehle, Robert, de Vries, Annelou, Paris, Francoise, Anna Nordenström, Annelou L.C. de Vries, Robert Roehle, Baudewijntje P.C. Kreukels, Bouvattier, Claire, null null, Birgit Köhler, Ute Thyen, Group, dsd-LIFE, Nordenström, Anna, Cohen-Kettenis, Peggy, Claire Bouvattier, Thyen, Ute   +18 more
core   +1 more source

Ovotesticular Disorders of sexual development (DSD): A rare case of peritoneal carcinomatosis in an elderly DSD male patient

Gynecologic Oncology Reports
Disorders of sexual development (DSDs) represent a spectrum of conditions characterized by atypical gonadal and/or genital development. The incidence is 1 in 5,000 live births.
Anastasia Navitski, Sakshi Sehgal, Kalyani Ballur, Lawrence C. Layman, Robert V. Higgins   +4 more
doaj   +1 more source

Glycaemic Changes After Semaglutide Discontinuation in Adults With Type 1 Diabetes Using Automated Insulin Delivery: Analysis of the ADJUST‐T1D Extension Study

Diabetes, Obesity and Metabolism, Volume 28, Issue 11, Page 10736-10742, November 2026.
ABSTRACT Aims To evaluate changes in glycaemic control following semaglutide discontinuation in adults with Type 1 diabetes and obesity who completed the ADJUST‐T1D randomised controlled trial. Materials and Methods Continuous glucose monitoring (CGM) data were collected during a 12‐week extension phase after the ADJUST‐T1D trial.
Eslam Montaser, Kanchan Bhasin, Davida Kruger, Halis Kaan Akturk, Andrew Ahmann, Janet K. Snell‐Bergeon, Viral N. Shah   +6 more
wiley   +1 more source

Whole-genome de novo sequencing reveals genomic variants associated with differences of sex development in SRY negative pigs

Biology of Sex Differences
Background Differences of sex development (DSD) are congenital conditions in which chromosomal, gonadal, or phenotypic sex is atypical. In more than 50% of human DSD cases, a molecular diagnosis is not available.
Jinhua Wu, Shuwen Tan, Zheng Feng, Haiquan Zhao, Congying Yu, Yin Yang, Bingzhou Zhong, Wenxiao Zheng, Hui Yu, Hua Li   +9 more
doaj   +1 more source

Ensuring connectedness for the maximum quasi‐clique and densest k‐subgraph problems

International Transactions in Operational Research, Volume 33, Issue 6, Page 3800-3824, November 2026.
Abstract Given an undirected graph G$G$, a quasi‐clique is a subgraph of G$G$ with density at least γ$\gamma$ (0<γ≤1)$(0 < \gamma \le 1)$. Two optimisation problems can be defined for quasi‐cliques: the maximum quasi‐clique (MQC) problem, which finds a quasi‐clique with maximum vertex cardinality, and the densest k$k$‐subgraph (DKS) problem, which ...
Daniela Scherer dos Santos, Kathrin Klamroth, Pedro Martins, Luís Paquete   +3 more
wiley   +1 more source

Clinicoepidemiological Profile of Disorders of Sex Development Presenting to a Tertiary Care Center: A Descriptive Observational Study

Journal of Indian Association of Pediatric Surgeons
Background and Objective: The prevalence of disorders of sex development (DSD) is estimated to affect approximately 1 in 4500–5500 newborns, yet there is a dearth of studies, particularly in Central India, on this topic.
Sujeet Kumar Pandre, Pramod Kumar Sharma, Roshan Chanchlani, Mahesh Maheshwari, Suresh Kumar Thanneeru, Reyaz Ahmad   +5 more
doaj   +1 more source