Results 191 to 200 of about 62,177 (350)

Obesity‐Induced Metabolic Priming Exacerbates SARS‐CoV‐2 Inflammation

open access: yesImmunology, EarlyView.
Monocytes primed under obesogenic conditions, such as increased FFA levels (i.e., palmitate) exhibit exacerbated gene expression of inflammatory cytokines. The increased proinflammatory response of palmitate‐primed and SARS‐CoV‐2‐infected monocytes is not dependent on glycolytic metabolism but instead on the entry of FFAs into the mitochondria ...
Gustavo Gastão Davanzo   +28 more
wiley   +1 more source

Dupin: A Parallel Framework for Densest Subgraph Discovery in Fraud Detection on Massive Graphs (Technical Report) [PDF]

open access: yesarXiv
Detecting fraudulent activities in financial and e-commerce transaction networks is crucial. One effective method for this is Densest Subgraph Discovery (DSD). However, deploying DSD methods in production systems faces substantial scalability challenges due to the predominantly sequential nature of existing methods, which impedes their ability to ...
arxiv  

Visual DSD: a design and analysis tool for DNA strand displacement systems [PDF]

open access: hybrid, 2011
Matthew R. Lakin   +4 more
openalex   +1 more source

Switching PD‐1 to BRAF + MEK inhibition improves recurrence‐free survival in patients receiving a second course of adjuvant melanoma therapy

open access: yesJournal of the European Academy of Dermatology and Venereology, EarlyView.
66 patients from 22 centers received adjuvant treatment after relapse under or after previous adjuvant therapy with BRAF + MEK or PD‐1. Data highlight a significant benefit when switching from PD‐1 to BRAF + MEK adjuvant therapy compared to a switch from BRAF + MEK to PD‐1 adjuvant regimens.
Katharina Schumann   +25 more
wiley   +1 more source

Recognition of 5α-reductase-2 deficiency in an adult female 46XY DSD clinic [PDF]

open access: bronze, 2011
Marta Berra   +6 more
openalex   +1 more source

Whole-genome de novo sequencing reveals genomic variants associated with differences of sex development in SRY negative pigs

open access: yesBiology of Sex Differences
Background Differences of sex development (DSD) are congenital conditions in which chromosomal, gonadal, or phenotypic sex is atypical. In more than 50% of human DSD cases, a molecular diagnosis is not available.
Jinhua Wu   +9 more
doaj   +1 more source

DSD1/ZmICEb regulates stomatal development and drought tolerance in maize

open access: yesJournal of Integrative Plant Biology, EarlyView.
DECREASED STOMATAL DENSITY 1/INDUCER OF CBF EXPRESSION b regulates maize stomatal development and drought tolerance, providing a promising target for the genetic improvement of drought tolerance in maize by manipulating stomatal density. ABSTRACT Maize (Zea mays L.) growth and yield are severely limited by drought stress worldwide. Stomata play crucial
Wenqi Zhou   +11 more
wiley   +1 more source

A study on the application of nicenet for learning [PDF]

open access: yes, 2002
The aim of this research is to investigate how KUiTTHO students use an online forum in the process of learning; how KUiTTHO students communicate with their lecturer and the socio-linguistic aspect of using and online platform.
Kang, Sian Lee
core  

Investigating the Relation Between Second Language Proficiency and Study Success Using a Causal Inference Approach

open access: yesLanguage Learning, EarlyView.
Abstract Prior research suggests that second language (L2) proficiency is key in students’ study progress, but this research has mainly been carried out at universities. It is thus unclear how this relation varies across different educational levels. Moreover, previous studies are often not informative about the causality of this relation, making it ...
Sybren Spit, Sible Andringa, Oisín Ryan
wiley   +1 more source

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