Results 141 to 150 of about 91,317 (285)

Targeting necroptosis protects against astrocyte death and hippocampal sclerosis in experimental temporal lobe epilepsy

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Experimentally induced status epilepticus induces microglial TNFα release, which binds to astrocytic TNFR1 and triggers activation of RIPK1/RIPK3/MLKL signalling, initiating necroptotic astrocytic death that contributes to the development of hippocampal sclerosis. Created with Biorender.com.
Zhou Wu   +3 more
wiley   +1 more source

Impact of Mutational Landscape and Burden on RBC Transfusion Response in Patients With Lower‐Risk Myelodysplastic Syndromes (LR‐MDS) in the COMMANDS Study

open access: yesAmerican Journal of Hematology, Volume 101, Issue 3, Page 427-438, March 2026.
ABSTRACT The COMMANDS trial established luspatercept as a first‐line treatment for anemia in transfusion‐dependent lower‐risk (LR) myelodysplastic syndromes (MDS). Here we report red blood cell (RBC) transfusion response analysis based on somatic mutations profile and disease risk for patients treated with luspatercept or epoetin alfa in the COMMANDS ...
Rami S. Komrokji   +9 more
wiley   +1 more source

AI‐Powered Scoring for Creative Thinking: Methods and Challenges in PISA Assessment

open access: yesThe Journal of Creative Behavior, Volume 60, Issue 1, March 2026.
ABSTRACT The introduction of the PISA 2022 Creative Thinking assessment underscores the growing need for scalable, valid, and reliable methods to evaluate creativity in international large‐scale assessments. Traditional human scoring, while nuanced, is time‐consuming, costly, and subject to inconsistencies.
Ricardo Primi   +7 more
wiley   +1 more source

Association between household solid fuel use and dual sensory impairment in a Chinese population: a retrospective cohort study

open access: yesFrontiers in Public Health
AimDual sensory impairment (DSI) is more harmful than a single visual impairment or hearing impairment. We aimed to explore the relationship between household fuel use and the risk of DSI in the middle-aged and older adult Chinese population.MethodsData ...
Yaolei Du, Mengnan Wu, Mansha He
doaj   +1 more source

Anthropogenic interference and climatic change control long‐term dissolved silicate variation in the Yellow River

open access: yesLimnology and Oceanography Letters, Volume 11, Issue 2, March 2026.
Abstract Dissolved silicate (DSi) export from rivers is shaped by both natural processes and human activities. Using long‐term observations at Lijin station combined with chemical weathering and reservoir silicon cycling models, we reconstructed annual DSi fluxes and source‐sink dynamics in the Yellow River Basin since the 1980s.
Ke Wang   +5 more
wiley   +1 more source

The Role of Creativity and Innovation Management Research in Times of Changing Security and Defence Realities

open access: yesCreativity and Innovation Management, Volume 35, Issue 1, Page 84-90, March 2026.
ABSTRACT Geopolitical uncertainties and the resurgence of security and defence needs present both opportunities and challenges for creativity and innovation management. At both the organizational and the individual levels, we are confronted with multiple ethically challenging choices. Given the changing global security and defence realities, we outline
Mette Præst Knudsen   +4 more
wiley   +1 more source

Interobserver variability of histopathological assessment in pT1 colorectal carcinoma

open access: yesHistopathology, Volume 88, Issue 4, Page 868-880, March 2026.
Interobserver variability among 20 gastrointestinal pathologists was evaluated on 80 pT1 colorectal carcinoma cases. A pilot phase was followed by a consensus meeting, then a larger concordance study was performed. High interobserver agreement was achieved after consensus for histological grade, lymphovascular invasion, tumour budding, poorly ...
Karmele Saez de Gordoa   +24 more
wiley   +1 more source

Whole‐bone shape of hominoid manual proximal phalanges

open access: yesThe Anatomical Record, Volume 309, Issue 2, Page 245-270, February 2026.
Abstract Functional morphologists have long noted that skeletal adaptations in primate phalanges reflect locomotor behavior. While most studies have successfully used two‐dimensional measurements to quantify general features of phalanx shape, a whole‐bone three‐dimensional analysis may better capture more subtle aspects of phalanx morphology that have ...
Deanna M. Goldstein   +7 more
wiley   +1 more source

Barium‐Catalyzed Dehydrocoupling of Terminal Alkynes and Hydrosilanes

open access: yesChemistryEurope, Volume 4, Issue 2, February 2026.
A combined experimental, kinetic, and theoretical investigation reveals that molecular barium catalysts mediate competently the controlled dehydrocoupling of terminal alkynes and hydrosilanes for the production of alkynylsilanes. The dehydrocoupling of terminal alkynes and hydrosilanes catalyzed by alkaline‐earth complexes: calcium, strontium and, most
Sakshi Mohan   +4 more
wiley   +1 more source

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