Results 61 to 70 of about 10,536 (218)

Fitness beyond age: Multidisciplinary expert opinion on redefining fitness for targeted therapies in chronic lymphocytic leukemia

HemaSphere, Volume 10, Issue 2, February 2026.
Abstract Advancements in the understanding of chronic lymphocytic leukemia (CLL) have transformed patient care, leading to the development of novel targeted therapies. Traditionally, patient fitness for treatment was based on the tolerability of chemoimmunotherapy such as fludarabine–cyclophosphamide–rituximab.
Raúl Córdoba, Stephan Stilgenbauer, Paolo Ghia, Alessandra Tedeschi, Lindsey Roeker, Myriam Rodriguez‐Couso, Stephen P. Mulligan, Samir Kanaan Nabhan, Jan Rynne, Teresa López‐Fernández   +9 more
wiley   +1 more source

SGLT2 inhibitor or metformin as standard treatment in early‐stage type 2 diabetes? Baseline data in SMARTEST, a novel, decentralised, register‐based randomised trial on prevention of diabetic complications

Diabetes, Obesity and Metabolism, Volume 28, Issue 2, Page 1327-1338, February 2026.
Abstract Aims Metformin has hitherto not been proven superior to other type 2 diabetes (T2D) medications for the prevention of organ complications. The aim of this study is to report baseline data and blinded interim analyses in the register‐based randomised clinical trial (RRCT) SMARTEST, which compares metformin and the SGLT2 inhibitor dapagliflozin ...
Jan W. Eriksson, Giovanni Fanni, Martin H. Lundqvist, Stefan Jansson, Karin Rådholm, Sheyda Sofizadeh, Vagia Patsoukaki, Albert Nilsson, Daniel Lindholm, Olov Rolandsson, Anna Norhammar, Elisabet Granstam, Björn Eliasson, Louise Bennet, Johan Sundström   +14 more
wiley   +1 more source

Modelling, Simulation and Dynamic Sliding Mode Control of a MEMS Gyroscope

Micromachines, 2021
An adaptive dynamic sliding mode control via a backstepping approach for a microelectro mechanical system (MEMS) vibratory z-axis gyroscope is presented in this paper. The time derivative of the control input of the dynamic sliding mode controller (DSMC)
Yunmei Fang, Wen Fu, Cuicui An, Zhuli Yuan, Juntao Fei   +4 more
doaj   +1 more source

A wall-function approach to incorporating Knudsen-layer effects in gas micro flow simulations [PDF]

, 2004
For gas flows in microfluidic configurations, the Knudsen layer close to the wall can comprise a substantial part of the entire flow field and has a major effect on quantities such as the mass flow rate through micro devices.
Gallis, Michael A., Lockerby, Duncan A., Reese, Jason   +2 more
core   +1 more source

Characterization of Korean Colorectal Cancer Reveals Novel Driver Gene and Clinically Relevant Mutations

MedComm, Volume 7, Issue 1, January 2026.
This study utilizes whole‐genome sequencing of 197 paired samples to conduct mutational profiling of colorectal cancer (CRC) in Korean patients, identifying novel driver genes associated with recurrence. The research provides insights into oncogenic pathways and highlights clinically significant variants, emphasizing the importance of ethnic diversity ...
Junho Kang, Dong Min Lim, Young‐Joon Kim, Hyeran Shim, Tae‐You Kim, Kyu Joo Park, Sung‐Bum Kang, Chang Sik Yu, Jong Lyul Lee, Yeuni Yu, Hansong Lee, Eun Jung Kwon, Hyo Min Kim, Seongik Mun, Donghee Kwak, Hae Seul Lee, Hye Jin Heo, Eun Kyoung Kim, Seung Eun Baek, Jong‐Wook Park, Sung Uk Bae, Taeg Kyu Kwon, Dongjun Lee, Kihun Kim, Chang‐Kyu Oh, Dai Sik Ko, Sunghwan Cho, Hae Ryoun Park, Shin Kim, Yun Hak Kim   +29 more
wiley   +1 more source

Statistical Error in Particle Simulations of Hydrodynamic Phenomena

, 2002
We present predictions for the statistical error due to finite sampling in the presence of thermal fluctuations in molecular simulation algorithms. Specifically, we establish how these errors depend on Mach number, Knudsen number, number of particles ...
Alejandro L. Garcia, Alexander, Alexander, Alexander, Allen, Bird, Feller, Frenkel, Fürth, Gang He, Garcia, Garcia, Garcia, Ghosal, Hadjiconstantinou, Hadjiconstantinou, Johnson, Landau, Landau, Landau, Liu, Malek-Mansour, Martin Z. Bazant, Nicolas G. Hadjiconstantinou, Taylor   +24 more
core   +1 more source

The High Plasma Density Observed Along the PJ57 Juno Flyby of Io Implies the Presence of a Dense Atomic Corona

Journal of Geophysical Research: Space Physics, Volume 131, Issue 1, January 2026.
Abstract On December 2023, the Juno spacecraft made a flyby of Io above the northern hemisphere at a closest approach (CA) altitude of ∼1,500 km (PJ57). The Juno/Waves and Radio‐occultation measurements showed a surprising large electron density ∼28,000 cm−3 near closest approach.
V. Dols, F. Bagenal
wiley   +1 more source

DSMC: A Novel Distributed Store-Retrieve Approach of Internet Data Using MapReduce Model and Community Detection in Big Data

International Journal of Distributed Sensor Networks, 2014
The processing of big data is a hotspot in the scientific research. Data on the Internet is very large and also very important for the scientific researchers, so the capture and store of Internet data is a priority among priorities.
Xu Xu, Jia Zhao, Gaochao Xu, Yan Ding, Yunmeng Dong   +4 more
doaj   +1 more source

Modeling and Design of ANFIS Dynamic Sliding Mode Controller for a Knee Orthosis of Hemiplegia

Applied Bionics and Biomechanics, 2023
The use of assistive devices to control the loss of strength and range of motion of hemiplegic patients is becoming common. It is difficult to develop a precise control approach for a knee orthosis system because of the unpredictability of the dynamics ...
Belay Eshetu, Solomon Seid
doaj   +1 more source

Unified Gas-kinetic Scheme with Multigrid Convergence for Rarefied Flow Study

, 2017
The unified gas kinetic scheme (UGKS) is a direct modeling method based on the gas dynamical model on the mesh size and time step scales. With the implementation of particle transport and collision in a time-dependent flux function, the UGKS can recover ...
Xu, Kun, Zhong, Chengwen, Zhu, Yajun
core   +2 more sources