Results 141 to 150 of about 258,335 (279)

Different Pattern of Treatment Failure After Chemoradiation Between p16+ and p16− Patients Affected by Oropharyngeal Carcinoma

Head &Neck, EarlyView.
ABSTRACT Background Oropharyngeal cancer (OPC) exhibits distinct clinical behaviors according to HPV/p16 status and smoking exposure. While HPV‐positive OPC generally shows superior survival, differences in recurrence patterns remain unclear. Methods A retrospective multicenter analysis of 674 AJCC VII edition Stage III–IVa/b OPC patients treated with ...
Riccardo Gili, Paolo Bossi, Luca Lalli, Lisa Francesca Linda Licitra, Marta Maddalo, Almalina Bacigalupo, Liliana Belgioia, Jon Cacicedo, Nadia Facchinetti, Almudena Garcia Castano, Marc Oliva, Pierluigi Bonomo, Giuseppe Sanguineti, Pierfrancesco Franco, Athanassios Argiris, Amanda Psyrri, Ester Orlandi   +16 more
wiley   +1 more source

An Optimization-Based Decision Support System for Strategic Planning in a Process Industry: The Case of an Aluminum Company in India [PDF]

We describe how a generic multi-period optimization-based decision support system (DSS) can be used for strategic planning in process industries. The DSS is built on five fundamental elements .
Dutta, Goutam, Gupta, Narain, Robert Fourer   +2 more
core  

Longitudinal changes in health‐related quality of life after a breast cancer diagnosis in sub‐Saharan Africa: Evidence from the prospective ABC‐DO cohort

International Journal of Cancer, EarlyView.
What's New? Breast cancer is now the most common malignancy among women in sub‐Saharan Africa (SSA). Its impact on survivors’ quality of life and Global Health Status (GHS), however, remains inadequately studied in this setting. Here, using data from the African Breast Cancer‐Disparities in Outcomes (ABC‐DO) study, the authors examined GHS over time in
Shamsudeen Mohammed, Moses Galukande, Allen Naamala, Groesbeck Parham, Leeya Pinder, Angelica Anele, Shadrach Awa Offiah, Annelle Zietsman, Joachim Schüz, Valerie McCormack, Isabel dos‐Santos‐Silva   +10 more
wiley   +1 more source

Evolutifon of decision support system architectures: applications to land planning and management in Cuba

Journal of Computer Science and Technology, 2003
The main objective of this paper centers on reviewing the evolution of Decision Support System´s (DSS) architectures, particularly as they apply to natural resources.
Saddys Segrera, Raúl Ponce-Hernandez, J. Arcia   +2 more
doaj  

Cohort study of standardized treatment pathways by multidisciplinary tumor board decision making in patients with salivary gland malignancies

International Journal of Cancer, EarlyView.
What's New? The overall survival of patients with salivary gland malignancies has shown limited progress. Here, the authors evaluated the impact of establishing a multidisciplinary tumor board to ensure standardized diagnostic and treatment procedures at a certified cancer center.
Nils Feldmann, Gunnar Wichmann, Andreas Dietz, Markus Pirlich   +3 more
wiley   +1 more source

Napabucasin transforms liver microenvironment and boosts immunotherapy efficacy by converting potential metastases into “hot” tumors

Interdisciplinary Medicine, EarlyView.
Napabucasin reduces liver metastases by reprogramming the hepatic microenvironment. It induces hepatocyte secretion of CCL21 via c‐Fos activation, recruiting lymphocytes and converting “cold” metastases into immunologically “hot” tumors. This effect is liver‐specific and independent of cancer cells.
Qiongqiong Wang, Jiaqi Zhou, Hang Qiao, Yifan Jia, Ling Ye, Zeli Li, Jiahe Ouyang, Haoxian Zhou, Kangxin Zeng, Xuemeng Wang, Yixian Wang, Yang Zhang, Yupeng Zhang, Yizhou Cai, Yutao Hu, Minzhe Zhang, Wenwei Xu, Zhenzhen Wu, Xiaofang Qiu, Li Lin   +19 more
wiley   +1 more source

Multimodal MRI and multiomics reveal high‐risk neurophenotype in brain‐gut circuits as therapeutic target for Crohn's disease

Interdisciplinary Medicine, EarlyView.
Through a translational framework combining prospective dual‐center clinical cohorts with dextran sulfate sodium‐induced colitis models, this work integrated advanced neuroimaging, multi‐omics and neuromodulation interventions to redefine the high‐risk neurophenotype as a sustained pathogenic driver rather than a mere phenomenon, proposing brain‐gut ...
Xuehua Li, Ruonan Zhang, Xiaodi Shen, Shaochun Lin, Chuhuai Wang, Weikai Zheng, Weimiao Kong, Zihao Lin, Rongchang Li, Caiguang Liu, Xin Cao, Li Huang, Weitao He, Jinjiang Lin, Haijie Wang, Zhoulei Li, Marietta Iacucci, Subrata Ghosh, Zhenpeng Peng, Canhui Sun, Minhu Chen, Guang Yang, Yejun Wang, Ren Mao, Shi‐Ting Feng   +24 more
wiley   +1 more source

Towards Water, Food and Energy Security: The Global Challenges and Possible Solutions for a Holistic Vision of Sustainability

Irrigation and Drainage, EarlyView.
ABSTRACT This invited paper gives an overview of the challenges the world is facing and offers a possible solution for water and food security within the holistic integrated concept of the water–energy–food (WEF) nexus. The paper summarizes the experience the author gained through working on various research projects at national and international ...
Ragab Ragab
wiley   +1 more source

Seasonal Predictions and Their Applications in the Mediterranean Region: Part II—Prediction‐Based Services

International Journal of Climatology, EarlyView.
This review explores climate predictions as actionable decision‐making tools, focusing on the Mediterranean. It examines transforming forecasts into user‐defined information through bias adjustment, downscaling and impact models. Highlighting collaborative EU initiatives, it addresses challenges like limited forecasting skill and data accessibility ...
Silvio Gualdi, Ernesto Rodriguez Camino, Esteban Rodriguez Guisado, Andrea Toreti, Massimiliano Pasqui, Constantin Ardilouze, Wafae Badi, Lauriane Batté, Fatima Driouech, Kristina Fröhlich, Javier García‐Serrano, Silvia Terzago, Veronica Torralba   +12 more
wiley   +1 more source

STING pathway contributes to Steroid-Hyporesponsive Lung Inflammation in DSS-induced colitis mice model. [PDF]

PLoS One
Eladham MW, Sharif-Askari NS, Mdkhana B, Ali S, Al-Sheakly BKS, Ali N, Selvakumar B, Sharif-Askari FS, Hachim I, Halwani R.   +9 more
europepmc   +1 more source