Results 171 to 180 of about 20,471 (284)

Cost-Effectiveness of Differential Target Multiplexed Spinal Cord Stimulation for the Treatment of PSPS Type 1 from the Belgian Perspective. [PDF]

open access: yesJ Pain Res
Smet I   +7 more
europepmc   +1 more source

Detection of protein symmetry and structural rearrangements using secondary structure elements

open access: yesProtein Science, Volume 35, Issue 6, June 2026.
Abstract Many proteins exhibit a degree of internal symmetry in their tertiary structure, including circular permutations. These characteristics play an important role in terms of the functional robustness of proteins against mutations, and are pivotal for the study of protein function and evolution.
Runfeng Lin, Sebastian E. Ahnert
wiley   +1 more source

Stability and cooperativity in chimeric de novo TIM barrels via quarter swapping

open access: yesProtein Science, Volume 35, Issue 6, June 2026.
Abstract The use of repetitive units as building blocks in protein design, mimicking evolutionary duplication events, is a valuable strategy that reduces structural complexity. Such modular designs offer an opportunity to dissect how local contributions are integrated in a context‐dependent manner.
Oscar Rodríguez‐Meza   +5 more
wiley   +1 more source

June 17, 1993 4:09 pm The DTM Gigabit Network

open access: yes, 2008
DTM is a fiber-optic network, based on bandwidth reservation and with support for dynamic reallocation of bandwidth. It is designed for real-time multimedia applications and for high-speed computer communication.
Per Lindgren   +3 more
core  

Covalent drug rescue of multiple p53 mutants by stabilizing vinyl sulfone fragments hints to a specific refolding mechanism for R282W

open access: yesProtein Science, Volume 35, Issue 6, June 2026.
Abstract The tumor suppressor protein p53 plays a crucial role in cell cycle regulation. In approximately 50% of all tumors, mutations in p53 are observed. Although the top hot spot mutations impair DNA binding, other mutations affect the thermal stability of the protein, leading to its rapid denaturation in physiological conditions.
Jason Stahlecker   +9 more
wiley   +1 more source

Closed-loop SCS and sensing: now and in the future. [PDF]

open access: yesPain Med
Chakravarthy K   +14 more
europepmc   +1 more source

Trace Metal Biogeochemistry in the Nordic Seas: Arctic and Atlantic Water Inflows Determine (Micro)Nutrient Availability

open access: yesGlobal Biogeochemical Cycles, Volume 40, Issue 6, June 2026.
Abstract We present a data set of macronutrient and dissolved and total dissolvable trace metal concentrations collected in June 2012 across the Nordic Seas. Surface water and depth profiles of manganese, iron, cobalt, nickel, copper, zinc, phosphate, silicic acid, and NOx (nitrate + nitrite) reveal how warm saline Atlantic waters and cold fresh Arctic
Yaqing Ruan   +6 more
wiley   +1 more source

Validating self-reported exclusive breastfeeding in Eswatini using stable isotope techniques. [PDF]

open access: yesPLoS One
Simelane KS   +7 more
europepmc   +1 more source

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