Results 201 to 210 of about 20,471 (284)

Exact and numerical optical soliton solutions of the fractional quadratic-cubic nonlinear Schrödinger equation in conformable derivative framework. [PDF]

Sci Rep
Amer A, Jaradat EK, Rehman HU, Yildirim Y, Abu Alrub S, Ateto MS.   +5 more
europepmc   +1 more source

Influence of the Uncertainty in the Dam‐Breach Hydrograph on the Flood Hazard Assessment in a Valley Area

Journal of Flood Risk Management, Volume 19, Issue 2, June 2026.
ABSTRACT The reliability of flood event simulations is a crucial aspect in terms of saving lives. The worst flood scenarios derive from possible dam failures. For earthen dams, the breaching mechanism, triggered by overtopping or piping, is affected by several modelling uncertainties, which propagate downstream and may influence flood hazard mapping ...
Andrea Antonella Graziano, Domenico Ferraro, Francesco Macchione   +2 more
wiley   +1 more source

Poor agreement between methods used in population studies to estimate the volume of human milk consumed: a Bland-Altman analysis. [PDF]

Int Breastfeed J
Lima Cavalcanti AA, Gonçalves VSS, Pizato N, Patriota ÉSO, Guimarães BAE, Coutinho IM, da Costa THM.   +6 more
europepmc   +1 more source

On optimum end-to-end distortion in wideband MIMO systems

, 2010
Chen, Jinhui; Slock, DTM
core  

Development of a Lysine‐Reactive Targeted Covalent Inhibitor for the P300/CBP‐Associated Factor Bromodomain Through Structure‐Based Design

ChemMedChem, Volume 21, Issue 10, 27 May 2026.
We developed a targeted covalent inhibitor for the p300/CBP‐associated factor (PCAF) bromodomain. Our lead molecule, 10, labeled a unique lysine residue in the PCAF bromodomain, demonstrated potent inhibition in biophysical/biochemical assays, and engaged the PCAF bromodomain in cells.
Richard R. Ede, Kerstin E. Peterson, Richard K. Begyinah, Irin P. Tom, Jason M. Ochoada, Molly S. Sneddon, Ana Katrina Y. Tiu, Marcus Fischer, Anang A. Shelat, William C. K. Pomerantz   +9 more
wiley   +1 more source

Deep plowing improves soil physical structure and alters nitrogen-cycling microbial communities in a subtropical red soil region. [PDF]

Front Microbiol
Li X, Liu Y, Pu Y, Shen G, Gao S, Kuang S, Song W, Cong P.   +7 more
europepmc   +1 more source

Identification of 2‐Substituted‐3‐Hydroxy‐2,3‐Dihydroquinazolin‐4(1H) Ones as Cell‐Active Inhibitors of KDM4A Lysine Demethylase

ChemMedChem, Volume 21, Issue 10, 27 May 2026.
A novel 3‐hydroxy‐2,3‐dihydroquinazolinone scaffold is identified as a cell‐active KDM4A inhibitor through an orthogonal screening cascade minimizing assay interference. Integrated biochemical, biophysical, and proteomic validation reveals compound 6i as a bona fide binder that increases H3K9 methylation in cells, highlighting both a promising ...
Alessandra Feoli, Amodio Luca Balzano, Ida Pacilio, Alessandra Cipriano, Roman Belle, Giacomo Pepe, Manuela Giovanna Basilicata, Pietro Campiglia, Fabrizio Micheli, Akane Kawamura, Ciro Milite, Sabrina Castellano, Axel Imhof, Gianluca Sbardella   +13 more
wiley   +1 more source

Polysaccharide from <i>Gleditsia sinensis</i> Seed Endosperm Ameliorates Type 2 Diabetes and Its Associated Cardiorenal Injuries by Modulating TLR4/MyD88/NF-κB Pathway and Gut Microbiota. [PDF]

Metabolites
Liu M, Liao W, Liu H, Xu F, Zhang Y, Wang X, Wu H.   +6 more
europepmc   +1 more source

Synergistische Entwicklungsstrategien von Inhibitoren gegen humane UDP‐Galactose‐4‐Epimerase

Angewandte Chemie, Volume 138, Issue 22, 25 May 2026.
Die Epimerase GalE ist essenziell für die Biosynthese von krebsrelevanten O‐GalNAc Glykanen. Wir verwenden orthogonales, strukturbasiertes Screening niedermolekularer Fragmente an, um kovalente und nichtkovalente Inhibitoren gegen GalE mit nicht mehr als 22 optimierten Verbindungen zu erhalten.
William M. Browne, Jonathan Pettinger, Teresa Weckwerth, Andrew Purkiss, Sing Hei Lok, Louisa Penicaut, Roksana Ogrodowicz, Raveena Prema, Simone Kunzelmann, Chloe Roustan, Ganka Bineva‐Todd, Saskia Pieters, Francesca Zappacosta, Alfred E. Doherty, Isobel Oram, Christelle Soudy, Robert Quinlan, Joanna Redmond, Svend Kjaer, David House, Stephane Mouilleron, Jacob T. Bush, Benjamin Schumann   +22 more
wiley   +1 more source

Unfolding the policy dynamics of medical data assetization in Chinese public healthcare institutions: evidence from Latent Dirichlet Allocation and dynamic topic modeling analysis. [PDF]

Front Public Health
Han S, Zeng Q, Cui X, Ji Y, Liu K, Li N, Cheng Y.   +6 more
europepmc   +1 more source