Results 221 to 230 of about 60,907 (302)

Photoinduced Cross-Metal Charge Transfer over Dual-Atom Z‑Scheme Catalysts Governing Cooperative Urea Synthesis from CO₂ and N₂. [PDF]

JACS Au
Lin CB, Sun FL, Chen WX, Zhao J, Wong MW, Zhuang GL.   +5 more
europepmc   +1 more source

Nanotherapies for Atherosclerosis: Targeting, Catalysis, and Energy Transduction

Advanced Healthcare Materials, EarlyView.
Atherosclerosis management is hindered by poor drug targeting and plaque heterogeneity. Nanotechnology overcomes these barriers via three core strategies: (1) target‐engineered nanocarriers that achieve lesion‐specific precision via ligand modification, biomimetic camouflage, stimuli‐responsive release, and self‐propelling nanomotors; (2) catalytic ...
Yuqi Yang, Jingguo Qu, Tonghuan Xiao, Xinyang Han, Michael Tin‐Cheung Ying   +4 more
wiley   +1 more source

Bridging the Gap: The PrEP Cascade Paradigm Shift for Long-Acting Injectable HIV Prevention. [PDF]

Viruses
Demidont ACA.
europepmc   +1 more source

Tuning the Testicular Microenvironment for Enhancing Human Sertoli Cells Maturation and Functionality In Vitro

Advanced Healthcare Materials, EarlyView.
An in vitro testicular model is developed by generating connective tissue equivalents from human dermal fibroblast‐derived microtissues and coupling them with human Sertoli cells or human Sertoli cell spheroids. This engineered microenvironment supports Sertoli cell maturation and functionality, providing a promising platform for studying human ...
Annachiara Scalzone, Giorgia Imparato, Chiara Ausilio, Valentina Mollo, Paolo Antonio Netti   +4 more
wiley   +1 more source

Dual-Site Acetylcholinesterase Inhibition and Multiscale Stability of Fused Quinoline Sulfonamides: A Chemoinformatic GA-MLR and Molecular Dynamics Study. [PDF]

Int J Mol Sci
Nilewar SS, Chavan AD, Pradhan AR, Tripathy AA, Bandaru N, Dudhe PB, Kumar PK, Lodha S, Muteeb G, Peredo-Valderrama I, Naranjo-Redondo AJ, Pawar TJ.   +11 more
europepmc   +1 more source

Respiratory Organ‐on‐a‐Chip for Disease Modeling: From Architecture to Functional Integration

Advanced Healthcare Materials, EarlyView.
Respiratory organ‐on‐a‐chip (ROC) models capture key mechanical and cellular cues of the human respiratory system, enabling quantitative dissection of disease mechanisms. This review links ROC architectures to disease modeling, functional integration, and commercialization, and proposes a decision framework that aligns model complexity with mechanistic
Jinzhuo Hu, Yongjie Tang, Sidi Liu, Tao Xu, Qian Liu   +4 more
wiley   +1 more source

A perspective on magnetic ionic liquids as multifunctional platforms for drug delivery and biomedical applications. [PDF]

Discov Nano
Mishra AK, Acharya S, Jain A.
europepmc   +1 more source

Photothermal‐Activated Antibacterial Amyloid‐Polyphenol‐Iron Hydrogels for Synergistic Wound Healing

Advanced Healthcare Materials, EarlyView.
We report a thermally triggered supramolecular hydrogel (LTFe) formed by Fe3+ and tannic acid on lysozyme amyloid fibrils. Fe3+ enables rapid gelation and photothermal transduction with an efficiency of 88.56%. The LTFe hydrogel exhibits excellent biocompatibility, potent antibacterial activity against E. coli and S.
Di Wu, Jiangtao Zhou, Yang Shen, Qiyao Sun, Tong Li, Xiaoyang Zou, Bin Liu, Hongshan Liang, Raffaele Mezzenga   +8 more
wiley   +1 more source

Covalent inhibitor design confers activity against both GDP- and GTP-bound forms of KRAS G12C. [PDF]

Nat Commun
Condakes ML, Zhang Z, Danahy DB, Moore RR, Lakkaraju SK, Zhuo X, Amako Y, Borzilleri RM, Balachander SB, Chourb L, Civiello RL, Dongre AR, Downes DP, Drexler DM, Dudiak BM, Dzhekieva L, El-Samin M, Fink BE, Frederick K, Huang C, Khan J, Lees E, Levins CG, McCarthy C, Mintier GA, Mosure K, Parker MF, Powles R, Qi J, Ruzanov M, Sharma S, Sheriff S, Singh AK, Stedman J, Szapiel N, Thompson RL, Vaccaro W, Wang T, Yang T, You D, Meyer MJ, Bronson JJ, Stewart ML.   +42 more
europepmc   +1 more source

Microengineered Gradient Hydrogels for Mechanobiology

Advanced Healthcare Materials, EarlyView.
Gradient hydrogels are used to mimic the mechanical heterogeneity in native tissues, offering powerful in vitro platforms to study cell‐material interactions in diverse pathophysiological contexts. Here, we present a comprehensive review of the design and experimental considerations for stiffness gradient hydrogels, discussing exemplary achievements ...
Shin Wei Chong, Deepu Ashok, Anna Waterhouse, Marcela M. M. Bilek, Daniele Vigolo   +4 more
wiley   +1 more source