Results 41 to 50 of about 66,638 (258)

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

open access: yesFEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee   +2 more
wiley   +1 more source

Reactive Power Controller for Single Phase Dual Active Bridge DC–DC Converters

open access: yesIEEE Access, 2023
In this study, we have proposed a triple-phase shift power-level controller (TPSPC) that achieves zero reactive power generation by fundamental components in a single-phase dual active bridge (DAB) DC-DC converter.
Hamid Naseem, Jul-Ki Seok
doaj   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

open access: yesFEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass   +2 more
wiley   +1 more source

High-Accuracy Generalized Average Model of Dual Active Bridge Converters

open access: yesIEEE Open Journal of Power Electronics
This article presents a detailed procedure for deriving the generalized average model (GAM) of a dual active bridge converter. The proposed model incorporates higher orders of harmonic components to increase accuracy. Moreover, the turn ratio of the high-
Rohan Shailesh Deshmukh   +2 more
doaj   +1 more source

Flux control modulation for the dual active bridge DC/DC converter

open access: yesThe Journal of Engineering, 2019
This paper introduces a modulation technique for the single-phase dual active bridge (DAB) in which the switching frequency and transformer flux linkage are modulated to achieve improved power transfer characteristics and reduced converter losses.
Niklas Fritz   +4 more
doaj   +1 more source

Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding

open access: yesFEBS Letters, EarlyView.
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança   +2 more
wiley   +1 more source

Application of Thermal Balance Phase-Shift Control Strategy to Dual-Active-Bridge DC-DC Converter [PDF]

open access: yesXibei Gongye Daxue Xuebao, 2018
With the development of the more/All electrical aircraft technology, the dual active bridge converter has been applied to the energy storage device to realize the bidirectional power flow in aircraft electrical system.

doaj   +1 more source

Performance Evaluation of Modulation Techniques in Single-Phase Dual Active Bridge Converters

open access: yesIEEE Open Journal of the Industrial Electronics Society, 2021
This research presents a thorough comparison of different modulation techniques employed in dual active bridge (DAB) converters. The performance of a DAB converter is essentially affected by the modulation technique and the operating point, including ...
Negar Noroozi, Ali Emadi, Mehdi Narimani
doaj   +1 more source

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

open access: yesFEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge   +6 more
wiley   +1 more source

The heterodimeric amino acid transporters (HAT) of the SLC7/SLC3 family: A structure−function relationships and relevance to human pathology

open access: yesFEBS Letters, EarlyView.
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise   +5 more
wiley   +1 more source

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