Investigating transcription factor dynamics in health and disease using FRAP
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
DUAL BAND FILTER DESIGN USING REAL FREQUENCY TECHNIQUE AND FREQUENCY TRANSFORMATION
In this work, we present a frequency transformation based dual-band filter design approach using scatteringbased real frequency technique. In the design process, conventional low-pass to band-pass frequency transformation isintegrated with the simplified
Serkan YILDIZ +2 more
doaj +2 more sources
A 24/77 GHz Dual-Band Receiver for Automotive Radar Applications
A fully-integrated 24/77 GHz dual-band receiver is presented for automotive radar applications. The proposed receiver consists of a dual-band LNA, a dual-band sub-sampling PLL, and a wideband mixer, operating at 24 and 77 GHz alternatively.
Xiang Yi +8 more
doaj +1 more source
An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg +14 more
wiley +1 more source
Currently, peak-to-average power ratio (PAPR) degrades the performance of the wireless system and has been widely studied in the orthogonal frequency division multiplexing (OFDM) systems.
Chen Changwei +4 more
doaj +1 more source
Realization of dual-band topological states in Su–Schrieffer–Heeger-like photonic crystal slabs
We design the bilayer mirror-symmetric (I-shaped) photonic crystal slabs supporting dual-band topological edge states simultaneously, which is confirmed by the topological phases and localized field distributions.
Ying Chen +4 more
doaj +1 more source
Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source
Behavioral Modeling and Predistortion of Dual-Band Power Amplifiers
Dual-band power amplifiers (PAs) are essential components in modern wireless communication systems. Compared to single band PAs, dual-band PAs enable efficient utilization of spectrum resources with lower capital and operational expenses.
Majid Ahmed +4 more
doaj +1 more source
Dual-Band RF Wireless Power Transfer System with a Shared-Aperture Dual-Band Tx Array Antenna
In this paper, a dual-band RF wireless power transfer (WPT) system with a shared-aperture dual-band Tx array antenna for 2.4 and 5.8 GHz is proposed. The final configuration of the Tx array, which is made up of 2.4 GHz right-handed circular polarization (
Chan-Mi Song +5 more
doaj +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source

