Results 81 to 90 of about 2,328,748 (310)

A DUAL-CHANNEL SUPPLY CHAIN MODEL OF COMPLEMENTARY PRODUCTS BY CONSIDERING GREEN MANUFACTURING LEVEL

Barekeng
The development of technology and the internet has encouraged industry players to develop their businesses by adding online sales media, which previously only used offline sales media.
Sabrina Sri Mulyani, Ririn Setiyowati, Nughthoh Arfawi Khurdi   +2 more
doaj   +1 more source

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

Molecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu, Nicolas J. Niklaus, Anna M. Schläfli, Igor Tokarchuk, Magali Humbert, Federico La Manna, Bich Vu, David Maul, Ramin Radpour, Marianna Kruithof‐de Julio, Inti Zlobec, Jörn Dengjel, Bruce E. Torbett, Mario P. Tschan   +13 more
wiley   +1 more source

An Enhanced MIBKA-CNN-BiLSTM Model for Fake Information Detection

Biomimetics
The complexity of fake information and the inefficiency of parameter optimization in detection models present dual challenges for current detection technologies.
Sining Zhu, Guangyu Mu, Jie Ma, Xiurong Li   +3 more
doaj   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source

Design of a Low-Cost Gateway with LoRa Technology Serving Multiple Devices

Sensors
The growing demand for scalability and efficiency in Low Power Wide Area Networks (LPWANs) presents significant challenges, particularly due to the increasing number of connected devices and the inherent limitations of the ALOHA protocol, which is widely
Wuigor I. S. Bine, Linnyer B. R. Aylon
doaj   +1 more source

Inhibition of cyclin‐dependent kinases 12/13 using CT7439 as a treatment for colorectal cancer with CDK12 upregulation

Molecular Oncology, EarlyView.
The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington, Divya L. Dayanidhi, Mohammad Zokaasadi, John B. Mantyh, Pelumi D. Olawuni, Gabrielle Rupprecht, Jeremy M. Force, Shannon McCall, Ashwani K. Bahl, David S. Hsu, Jason A. Somarelli   +10 more
wiley   +1 more source

Differential Game Analysis in a Dual-Channel Automotive Supply Chain Under the CAFC-NEV Credits and Carbon Credit Policies

World Electric Vehicle Journal
This paper focuses on alternatives to the CAFC-NEV credits policy in the automotive industry of China. It considers a dual-channel supply chain consisting of a manufacturer and a retailer that can simultaneously produce and sell new energy vehicles (NEVs)
Nan Liu, Shuyu Chen, Jun Kong, Tianze Zhang, Xiangdong Zhang   +4 more
doaj   +1 more source

Translating whole‐genome doubling into precision medicine in cancer

Molecular Oncology, EarlyView.
Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley   +1 more source

Dual-channel functional electrical stimulation improvements in speed-based gait classifications

, 2013
Shmuel Springer,1,2 Yocheved Laufer,1 Meni Becher,1,2 Jean-Jacques Vatine3,41Department of Physical Therapy, Faculty of Social Welfare and Health Sciences, University of Haifa, Haifa, 2Clinical Department, Bioness Neuromodulation, Ra'anana ...
Vatine JJ, Laufer Y, Springer S, Becher M   +3 more
core  

Understanding the key drivers of and technology related issues associated with going multi-channel [PDF]

, 2012
A multi-channel retail strategy is viewed by many academics and practitioners to be the success model for most retailers. Yet, while there are many drivers of, and advantages related to, using multiple channels to sell products and services to customers ...
Whysall, P, Foster, C, Lewis, J., Whysall, P., Lewis, J, Foster, Carley   +5 more
core