Results 71 to 80 of about 4,995,335 (310)

Strategic Analysis of the Recycler considering Consumer Behavior Based on E-Platform Recycling

Discrete Dynamics in Nature and Society, 2022
Internet + platform recycling is a new model of recycling that provides more ways to recycle WEEE. Considering consumers’ preference for channels, we construct a single-channel reverse supply chain model (Model-S) and two dual-channel reverse supply ...
Kaiwen Zheng, Hong Cheng, S.A. Edalatpanah, Bin Wang, Zihan Hao, Guang Peng   +5 more
doaj   +1 more source

Membrane composition and thermodynamic identity as boundaries of life for synthetic cell research

FEBS Letters, EarlyView.
What makes a cell a cell? The boundary of a living cell is not just a wall. Read as a Markov blanket, the membrane separates internal from external states, generating identity and non‐equilibrium order. Can this identity be rebuilt from scratch in a synthetic cell?
Caterina Presutti, Bert Poolman
wiley   +1 more source

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

Molecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu, Nicolas J. Niklaus, Anna M. Schläfli, Igor Tokarchuk, Magali Humbert, Federico La Manna, Bich Vu, David Maul, Ramin Radpour, Marianna Kruithof‐de Julio, Inti Zlobec, Jörn Dengjel, Bruce E. Torbett, Mario P. Tschan   +13 more
wiley   +1 more source

Research on Nash Equilibrium of Dual-Channel Supply Chain Based on Wholesale Price Discrimination and Sales Efforts

Discrete Dynamics in Nature and Society
The progress of communication technology and the Internet has made the dual-channel supply chain have great development. Supply chain members have to compete and cooperate with other enterprises on the chain in order to obtain greater self-benefit.
Jin Sha, Sisi Zheng
doaj   +1 more source

Decision and Coordination in a Dual-Channel Three-Layered Green Supply Chain [PDF]

Symmetry, 2018
This paper investigated, for the first time, the game and coordination of a dual-channel, three-layered, green fresh produce supply chain, with regard to its economic, social, and environmental performance. Considering that the market demand is dual-channel priced and sensitive to the degree of greenness and the freshness-level, four game models, under
Song, Zilong, He, Shiwei, An, Baifeng
openaire   +1 more source

Building the resilient supply chain. [PDF]

, 2004
In today’s uncertain and turbulent markets, supply chain vulnerability has become an issue of significance for many companies. As supply chains become more complex as a result of global sourcing and the continued trend to ‘leaning-down’, supply chain ...
Christopher, Martin, Helen Peck, Peck, Helen, Martin Christopher, Fábrega Garcia, Carmen Cecilia, Ahumada Ahumada, Javier Francisco   +5 more
core   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source

Innovation in humanitarian logistics and supply chain management: a systematic review

, 2023
The COVID-19 global health crisis forced border closings, strained resources and tightened funding, forcing humanitarian organisations to innovate. This paper aims to identify gaps in the literature on innovation in humanitarian supply chains, and to ...
Heaslip, G, Vaillancourt, Alain, Tatham, P, Altay, N, Tatham, Peter, Kovács, G, Heaslip, Graham, Spens, K, Vaillancourt, A, Kovács, Gyöngyi, Altay, Nezih, Spens, Karen   +11 more
core   +1 more source

Translating whole‐genome doubling into precision medicine in cancer

Molecular Oncology, EarlyView.
Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley   +1 more source

Online channel operation mode: Game theoretical analysis from the supply chain power structure

Journal of Industrial Engineering and Management, 2015
Purpose: Dual-channels have been widely used in practice, and the pricing decisions and the online channel operation mode choice have been the core problems in dual-channel supply chain management.
Song Huang, Guocan Chen, Yanan Ma
doaj   +1 more source