Results 41 to 50 of about 6,985,189 (226)

Dose‐dependent hepatotoxicity of hydrogen peroxide in HepG2 cells and its modulation by CYP450 induction

open access: yesFEBS Open Bio, EarlyView.
NMR metabolomics revealed concentration‐dependent metabolic perturbations in HepG2 cells exposed to H2O2. Rifampicin pretreatment enhanced metabolic competence, attenuated toxin‐induced alterations and produced metabolite profiles more consistent with human liver physiology, supporting the use of CYP450‐induced HepG2 models for improved in vitro ...
Maren Jinks   +4 more
wiley   +1 more source

Assessment of tibial fracture healing with dual energy X-ray absorptiometry: influence of metallic implants at the fracture site [PDF]

open access: yes, 1995
Evaluation of the progress of fracture healing traditionally combines manual fracture manipulation with a visual radiographic assessment. This approach can lead to satisfactory healing, but trouble can ensue when the type of fixation compromises the ...
Cattermole, Howard Charles
core  

Identification and characterization of a gene conferring stress resistance in Escherichia coli and cyanobacteria

open access: yesFEBS Open Bio, EarlyView.
Functional screening identified PcSyn14890, a cyanobacteria‐specific protein that enhances growth and stress resistance in E. coli and Synechocystis PCC6803. Although we expected it to function as a molecular chaperone, it was unable to protect against thermal aggregation of GAPDH.
Akiyo Yamada   +7 more
wiley   +1 more source

Annual Energy Outlook [PDF]

open access: yes, 2009
The Annual Energy Outlook 2009 (AEO2009), prepared by the Energy Information Administration (EIA), presents long-term projections of energy supply, demand, and prices through 2030, based on results from EIA’s National Energy Modeling System (NEMS).
United States. Energy Information Administration.
core   +1 more source

Deep learning reconstruction enhances tophus detection in a dual-energy CT phantom study

open access: yesScientific Reports
This study aimed to compare two deep learning reconstruction (DLR) techniques (AiCE mild; AiCE strong) with two established methods—iterative reconstruction (IR) and filtered back projection (FBP)—for the detection of monosodium urate (MSU) in dual ...
Sydney Alexandra Schmolke   +4 more
doaj   +1 more source

Dual-Energy Cone-Beam CT Using Two Complementary Limited-Angle Scans with A Projection-Consistent Diffusion Model

open access: yes
Background: Dual-energy imaging on cone-beam CT (CBCT) scanners has great potential in different clinical applications, including image-guided surgery and adaptive proton therapy. However, the clinical practice of dual-energy CBCT (DE-CBCT) has been hindered by the requirement of sophisticated hardware components.
Peng, Junbo   +7 more
openaire   +2 more sources

Artificial Intelligence in Systemic Sclerosis: Clinical Applications, Challenges, and Future Directions

open access: yesArthritis Care &Research, EarlyView.
Systemic sclerosis (SSc) is a rare autoimmune disease defined by immune dysregulation, vasculopathy, and progressive fibrosis of the skin and internal organs. Despite advances in care, major complications such as interstitial lung disease (ILD) and myocardial involvement remain the leading causes of morbidity and mortality.
Cristiana Sieiro Santos   +2 more
wiley   +1 more source

β‐Catenin/c‐Myc Axis Modulates Autophagy Response to Different Ammonia Concentrations

open access: yesAdvanced Biology, Volume 9, Issue 3, March 2025.
Ammonia, detoxified by the liver into urea and glutamine, impacts autophagy differently at varying levels. Low ammonia activates autophagy via c‐Myc and β‐catenin, while high levels suppress it. Using Huh7 cells and Spf‐ash mice, c‐Myc's role in cytoprotective autophagy is revealed, offering insights into hyperammonemia and potential therapeutic ...
S. Sergio   +11 more
wiley   +1 more source

Ontology‐Aligned Structuring and Reuse of Multimodal Materials Data and Workflows Toward Automatic Reproduction

open access: yesAdvanced Engineering Materials, EarlyView.
Reproduction of stacking fault energy calculations from literature with a semi‐automated large language model‐assisted extraction procedure: extraction of simulation protocol, atomistic structures, computational parameters, and reported results, ontology alignment, knowledge graph construction and, finally, recomputation forvalidation.
Sepideh Baghaee Ravari   +5 more
wiley   +1 more source

Performance Characteristics and Optimization of a Dual-Loop Cycle for a Domestic Refrigerator-Freezer [PDF]

open access: yes, 2012
A dual-loop cycle for a domestic refrigerator-freezer (RF) has a large energy saving potential because of lower compression ratio due to higher evaporating temperature in the fresh food compartment (R)-operation, and the individual optimization ...
Yoon, Won Jae   +2 more
core   +1 more source

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