Results 221 to 230 of about 12,402,633 (259)

Body Composition Phenotypes and Their Metabolic Associations in Treatment‐Naïve Patients With Newly Diagnosed Type 2 Diabetes: A DXA‐Based Cluster Analysis

open access: yesEndocrinology, Diabetes &Metabolism, Volume 9, Issue 6, November 2026.
Using dual‐energy X‐ray absorptiometry clustering of 185 treatment‐naïve type 2 diabetes patients, we identified four body‐composition phenotypes. Central‐obesity and high‐fat–high‐muscle clusters carried the highest fatty liver disease and hyperuricemia risk, whereas the low‐muscle cluster carried the highest osteoporosis risk.
Xintong Zhang, Rui Zhang, Tao Jiang
wiley   +1 more source

Consensus Guidelines for Diagnosis and Management of Pyruvate Dehydrogenase Complex Deficiency

open access: yesJournal of Inherited Metabolic Disease, Volume 49, Issue 6, November 2026.
ABSTRACT Primary pyruvate dehydrogenase complex deficiency (PDCD) comprises a group of monogenic disorders caused by pathogenic variants in genes encoding subunits of, or regulatory components affecting, the pyruvate dehydrogenase complex. The clinical phenotype spans a broad continuum, ranging from early onset congenital lactic acidosis to infantile ...
Nandaki Keshavan   +23 more
wiley   +1 more source

Whole Body Phase Angle as a Promising Marker of Disease Severity in Facioscapulohumeral Muscular Dystrophy

open access: yesMuscle &Nerve, Volume 74, Issue 5, Page 1443-1449, November 2026.
ABSTRACT Introduction/Aims To investigate its potential role as a marker of disease severity in facioscapulohumeral dystrophy (FSHD), this study examined the association between whole‐body phase angle (PhA) and clinically assessed severity in FSHD patients.
Oscar Crisafulli   +7 more
wiley   +1 more source

Compositional Data Analysis of Relative Body Mass and Physical Function Using the Relative Shift Approach

open access: yesObesity, Volume 34, Issue 11, Page 2020-2025, November 2026.
ABSTRACT Objective The purpose of this study was to present the novel relative shift approach for compositional data analysis of body composition as a predictor for gait speed and to compare it to existing methods. Methods Body composition was quantified from dual‐energy x‐ray absorptiometry in 145 older adults living with obesity.
Daniel P. Beavers   +5 more
wiley   +1 more source

Frequent Versus Single Active Bouts Differentially Affect Movement Behavior and Energy Balance in Adults With Overweight/Obesity

open access: yesObesity, Volume 34, Issue 11, Page 2072-2084, November 2026.
ABSTRACT Objective This study aimed to investigate the effects of breaking up sedentary behavior (SB) on daily movement behavior and energy balance in adults with overweight/obesity. Methods Thirty participants (16F/14M; 34.2 ± 7.3 years; 29.5 ± 3.2 kg/m2) were randomized to either BREAK (multiple 5‐min brisk walking bouts) or a duration‐matched ...
Heloisa C. Santo Andre   +13 more
wiley   +1 more source

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