Results 51 to 60 of about 38,712 (266)

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

open access: yesMolecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

Modeling and Optimization of Fuel-Mode Switching and Control Systems for Marine Dual-Fuel Engine

open access: yesJournal of Marine Science and Engineering, 2022
The marine dual-fuel engine can switch between diesel and gas modes according to the requirements of sailing conditions, fuel cost, and other working conditions to make sure the ship is in the best operating condition.
Zepeng Shu   +3 more
doaj   +1 more source

RoundMi: A quantitative method to analyze mitochondrial morphology in mitotic cells

open access: yesFEBS Open Bio, EarlyView.
RoundMi is a workflow for rapid analysis of mitochondrial morphology in mitotic cells. By combining adaptive preprocessing with automated segmentation and quantification, it enables accurate measurements from single focal plane images, reducing acquisition time and computational demands while remaining compatible with high‐throughput fixed and live ...
Elmira Parvindokht Bararpour   +2 more
wiley   +1 more source

Experimental study on the effect of load and air+gas/fuel ratio on the performances, emissions and combustion characteristics of diesel–LPG fuelled single stationary ci engine

open access: yesEngineering Reports, 2023
Due to the issue of combustion stability when using natural gas and the problem of knocking when using both natural gas and hydrogen, liquefied petroleum gas (LPG) is then a good candidate to use for the dual‐fuel concept since it has been proven to be a
Giovani Vidal Tchato Yotchou   +3 more
doaj   +1 more source

TEMPERATURE EXHAUST GAS ANALYSIS ON THE SHIP ENGINE

open access: yesRekayasa Mesin, 2022
Dual-fuel diesel engine is an engine with the use of two fuels in the combustion process to get labor on the engine. The types of fuels used include methane gas and marine gas oil fuels.
Dwi Prasetyo
doaj   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

open access: yesFEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova   +2 more
wiley   +1 more source

Optimization of Performance and Emissions of RCCI Engine at Various Speed Conditions Using Response Surface Methodology Technique

open access: yesEthiopian Journal of Science and Sustainable Development
The demand for reduction of greenhouse gases and the implementation of stringent emission regulations have compelled researchers and engine makers to look for alternative approaches of increasing efficiency from the internal combustion engine.
Negasa Tesfaye Tefera   +2 more
doaj   +1 more source

Optical investigation and thermodynamic analysis of premixed ammonia dual-fuel combustion initiated by dodecane pilot fuel

open access: yesFuel Communications, 2022
In view of reducing greenhouse gas emissions the transition from fossils fuels to sustainable energy carriers is a prerequisite to keep global warming within tolerable limits.
Silas Wüthrich   +5 more
doaj   +1 more source

Aging Is a Key Driver for Adult Acute Myeloid Leukemia

open access: yesAging and Cancer, EarlyView.
Acute myeloid leukemia (AML) is a classical age‐related hematologic malignancy, and a key driver of AML is aging, which profoundly regulates intrinsic factors such as genomic instability, epigenetic reprogramming, and metabolic dysregulation, and alters bone marrow microenvironment.
Rong Yin, Haojian Zhang
wiley   +1 more source

Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level

open access: yesAging and Cancer, EarlyView.
This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley   +1 more source

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