Targeting Lactate and Lactylation in Cancer Metabolism and Immunotherapy
Lactate, once deemed a metabolic waste, emerges as a central regulator of cancer progression. This review elucidates how lactate and its epigenetic derivative, protein lactylation, orchestrate tumor metabolism, immune suppression, and therapeutic resistance.
Jiajing Gong +5 more
wiley +1 more source
Experimental investigation and AI-based prediction of engine performance and emissions using CeO<sub>2</sub>-enhanced biodiesel blends. [PDF]
K G +4 more
europepmc +1 more source
Researchers identified a pancreatic cancer subset with low global protein synthesis but heightened translation of stress‐response genes like ATF4, rendering cells resistant to chemotherapy and apoptosis. These tumors depend on serine and cysteine from surrounding cancer‐associated fibroblasts (CAFs), which shift to produce serine by curbing collagen ...
Sauyeun Shin +25 more
wiley +1 more source
Towards Sustainable Development Goals: Application of Hydrogen-Enriched Mahua Biodiesel/Diesel Blend to Dual-Fuel Diesel Engine. [PDF]
Hoang AT +11 more
europepmc +1 more source
Machine Learning Discovery of Record‐Low Lattice Thermal Conductivity in Double Perovskites
A deep learning interatomic potential is introduced to predict forces for computing phonon properties and thermal transport behavior in double perovskites. Screening 9,709 compounds identifies 1,597 stable materials, and Boltzmann transport calculations including both three and four‐phonon scattering suggests a record‐low lattice thermal conductivity ...
Md Zaibul Anam +3 more
wiley +1 more source
Demonstration of particulate matter characterization from HVO-blended diesel using an integrated multi-instrument approach. [PDF]
Hodovány S +8 more
europepmc +1 more source
Tunable Switching Mechanisms in HfZrO2‐Based Tunnel Junctions for High‐Performance Synaptic Arrays
This work demonstrates hybrid switching in engineered HZO‐based FTJs, enabled by controlled interlayer design and oxygen scavenging dynamics. The combined switching mechanism produces robust multilevel conductance states in large crossbar arrays, offering a materials‐driven pathway toward scalable in‐memory computing with enhanced tunability and ...
Jiwon You +8 more
wiley +1 more source
Sustainable Gossypium arboreum biodiesel production using an industrial waste heterogeneous catalyst for RCCI engine applications. [PDF]
Rao TSSB +5 more
europepmc +1 more source

