Results 131 to 140 of about 6,390,692 (375)

On Humboldt on the Dual

open access: yes, 1989
This paper discusses the significance of Wilhelm von Humboldt's 1827 contribution "Ueber den Dualis", which was one of the first contributions to comparative grammar that studied a particular category, rather than classifying entire languages.
openaire   +1 more source

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

open access: yesMolecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak   +8 more
wiley   +1 more source

DUAL IN ŠIMUN KOŽIČIĆ BENJA’S MISAL HRUACKI

open access: yesFluminensia: Journal for Philological Research, 2012
The particularity of language present in the books printed in Šimun Kožičić Benja’s Glagolitic printing house in Rijeka has already been noticed in the literature.
Ivana Eterović, Blanka Ceković
doaj  

Un enfoque epistemológico para enseñar el concepto de energía en mecánica en cursos de Física Introductoria

open access: yesRevista Eureka sobre Enseñanza y Divulgación de las Ciencias
La energía es un concepto fundamental que permite la explicación y predicción de fenómenos en todos los campos de la física. Esto puede explicar que su comprensión se haya convertido en un objetivo de aprendizaje prioritario en los currículos de ciencias
Nicolás Gandolfo   +4 more
doaj   +1 more source

Dual Blockade of TNF and IL-17A Inhibits Inflammation and Structural Damage in a Rat Model of Spondyloarthritis [PDF]

open access: gold, 2022
Ihsan Hammoura   +10 more
openalex   +1 more source

Adaptaquin is selectively toxic to glioma stem cells through disruption of iron and cholesterol metabolism

open access: yesMolecular Oncology, EarlyView.
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié   +16 more
wiley   +1 more source

DVOJINA U JEZIKU TEKSTOVA HRVATSKOGLAGOLJIČKE NELITURGIJSKE KNJIŽEVNOSTI XV. STOLJEĆA

open access: yesRasprave Instituta za Hrvatski Jezik i Jezikoslovlje, 1999
Članak je posvećen opisu i problemima funkcioniranja dvojine kao elementa gramatičke kategorije broja u jeziku Petrisova zbornika (1468), najznačajnijega kodeksa glagoljaške neliturgijske književnosti XV. stoljeća.
Eduard Hercigonja
doaj  

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

open access: yesMolecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker   +16 more
wiley   +1 more source

Dual Drug Loaded Lipid Nanocarrier Formulations for Topical Ocular Applications

open access: yesInternational Journal of Nanomedicine, 2022
Ahmed Adel Ali Youssef,1,2 Narendar Dudhipala,2 Soumyajit Majumdar2,3 1Department of Pharmaceutical Technology, Faculty of Pharmacy, Kafrelsheikh University, Kafrelsheikh, 33516, Egypt; 2Department of Pharmaceutics and Drug Delivery, School of Pharmacy ...
Youssef AAA, Dudhipala N, Majumdar S
doaj  

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