Results 221 to 230 of about 6,390,692 (375)

Dual Antithrombotic Therapy with Dabigatran after PCI in Atrial Fibrillation

New England Journal of Medicine, 2017
C. Cannon, Deepak L. Bhatt, J. Oldgren, G. Lip, S. Ellis, Takeshi Kimura, M. Maeng, B. Merkely, U. Zeymer, S. Gropper, M. Nordaby, E. Kleine, Ruth Harper, Jenny Manassie, J. Januzzi, J. T. ten Berg, G. Steg, S. Hohnloser   +17 more
semanticscholar   +1 more source

Interplay between RNA‐protein interactions and RNA structures in gene regulation

FEBS Open Bio, EarlyView.
Methodological advances in mapping transcriptome‐wide RNA‐protein interactions and RNA structures have started to uncover the potential of RNP conformations in gene regulation. Competing RNA–RNA, RNA‐protein and protein–protein interactions shape the compaction and function of RNPs throughout their lifetime and may provide novel therapeutic targets in ...
Jenni Rapakko, Mauro Scaravilli, Minna‐Liisa Änkö   +2 more
wiley   +1 more source

Dual-energy computed tomography in children: Technique and clinical applications. [PDF]

World J Clin Pediatr
Saini S, Bhatia A, Bansal A, Saxena AK, Sodhi KS.   +4 more
europepmc   +1 more source

Lactoferrin treatment activates acetylcholinesterase, decreasing acetylcholine levels in non‐small cell lung cancer (NSCLC) cell culture supernatants, inhibiting cell survival

FEBS Open Bio, EarlyView.
Representation of the suggested mode of action of lactoferrin (Lf) in nonsmall cell lung cancer (NSCLC) A549 cells. Lf induces activation of caspase‐3 by activating p53 and AChE leading to decreased ACh concentrations. In turn, ACh signaling leads to activation of VEGF and AKT and blocking of caspase‐3.
Stuti Goel, Caroline Wozniak, Aya Sabri, Ben Haddad, Brooke Lopo, Alvaro Cobos, Sarah Sarofim, Jeffrey Guthrie, Deborah Heyl, Hedeel Guy Evans   +9 more
wiley   +1 more source

Antithrombotic Management in Patients With Atrial Fibrillation Following Percutaneous Coronary Intervention: An Updated Clinical Review. [PDF]

J Arrhythm
Saito Y, Kobayashi Y.
europepmc   +1 more source

Resolving inflammation: dual anti-inflammatory and pro-resolution lipid mediators

Nature reviews. Immunology, 2008
C. Serhan, Chia Nan, T. Dyke
semanticscholar   +1 more source

Overexpression of CDT1 inhibits cell cycle progression at S phase by interacting with the mini‐chromosome maintenance complex and causes DNA damage

FEBS Open Bio, EarlyView.
CDT1 is an essential protein for DNA replication licensing that loads the MCM complex, the eukaryotic replicative DNA helicase, onto replication origins. Overexpression of CDT1 induces cell cycle arrest at the S phase. Here we showed CDT1 inhibits the progression of replication forks by interacting with the MCM complex, leading to the stalling and ...
Takashi Tsuyama, Nonoka Takayama, Rina Tanaka, Yuuki Arai, Yohko Yamaguchi, Yuko Nawata, Yutaro Azuma, Shusuke Tada   +7 more
wiley   +1 more source

Molecularly Imprinted Membranes: Dual@MIPs@mbr for On-Site Detection of CA 19-9. [PDF]

Sensors (Basel)
Rodrigues E, Xu A, Sampaio P, Castro RC, Ribeiro DSM, Santos JLM, Piloto AML.   +6 more
europepmc   +1 more source

Metformin Protects against Radiation-Induced Pneumonitis and Fibrosis and Attenuates Upregulation of Dual Oxidase Genes Expression [PDF]

, 2018
Rasoul Azmoonfar, Peyman Amini, Hana Saffar, Saeed Rezapoor, Elahe Motevaseli, Mohsen Cheki, Rasoul Yahyapour, Bagher Farhood, Farzad Nouruzi, Ehsan Khodamoradi, Dheyauldeen Shabeeb, Ahmed Eleojo Musa, Masoud Najafi   +12 more
openalex   +1 more source

A general model for analysis of linear and hyperbolic enzyme inhibition mechanisms

FEBS Open Bio, EarlyView.
We developed a general enzyme kinetic model that integrates these six basic inhibition mechanism onto a single one. From this model, we deduced a general enzyme kinetic equation that through modulation of simple parameters, γ (the relative inhibitor affinity for two binding sites) and β (the reactivity of the enzyme–substrate–inhibitor complex), is ...
Rafael S. Chagas, Sandro R. Marana
wiley   +1 more source